3UGP
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![BU of 3ugp by Molmil](/molmil-images/mine/3ugp) | |
4LK1
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![BU of 4lk1 by Molmil](/molmil-images/mine/4lk1) | Crystal Structure Analysis of the E.coli holoenzyme | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Bae, B, Darst, S.A. | Deposit date: | 2013-07-05 | Release date: | 2013-11-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.8369 Å) | Cite: | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
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4LJZ
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![BU of 4ljz by Molmil](/molmil-images/mine/4ljz) | Crystal Structure Analysis of the E.coli holoenzyme | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Bae, B, Darst, S.A. | Deposit date: | 2013-07-05 | Release date: | 2013-11-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5871 Å) | Cite: | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
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4LK0
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![BU of 4lk0 by Molmil](/molmil-images/mine/4lk0) | Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex | Descriptor: | Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Bae, B, Darst, S.A. | Deposit date: | 2013-07-05 | Release date: | 2013-11-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.9103 Å) | Cite: | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
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4LLG
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![BU of 4llg by Molmil](/molmil-images/mine/4llg) | Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex | Descriptor: | Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Bae, B, Darst, S.A. | Deposit date: | 2013-07-09 | Release date: | 2013-11-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.7936 Å) | Cite: | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
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4KI2
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![BU of 4ki2 by Molmil](/molmil-images/mine/4ki2) | |
4OZ6
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![BU of 4oz6 by Molmil](/molmil-images/mine/4oz6) | Structure of the Branched Intermediate in Protein Splicing | Descriptor: | ALA-MET-ARG-TYR, MAGNESIUM ION, Mxe gyrA intein | Authors: | Bick, M.J, Liu, Z, Frutos, S, Vila-Perello, M, Debelouchina, G.T, Darst, S.A, Muir, T.W. | Deposit date: | 2014-02-14 | Release date: | 2014-05-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.786 Å) | Cite: | Structure of the branched intermediate in protein splicing. Proc.Natl.Acad.Sci.USA, 111, 2014
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8EHI
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![BU of 8ehi by Molmil](/molmil-images/mine/8ehi) | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (2) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | Deposit date: | 2022-09-14 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHF
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![BU of 8ehf by Molmil](/molmil-images/mine/8ehf) | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1) | Descriptor: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | Deposit date: | 2022-09-14 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EG8
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![BU of 8eg8 by Molmil](/molmil-images/mine/8eg8) | Cryo-EM structure of consensus elemental paused elongation complex with a folded TL | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | Deposit date: | 2022-09-12 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHA
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![BU of 8eha by Molmil](/molmil-images/mine/8eha) | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out) | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | Deposit date: | 2022-09-14 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EGB
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![BU of 8egb by Molmil](/molmil-images/mine/8egb) | Cryo-EM structure of consensus elemental paused elongation complex with an unfolded TL | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | Deposit date: | 2022-09-12 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EG7
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![BU of 8eg7 by Molmil](/molmil-images/mine/8eg7) | Cryo-EM structure of pre-consensus elemental paused elongation complex | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | Deposit date: | 2022-09-11 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EH8
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![BU of 8eh8 by Molmil](/molmil-images/mine/8eh8) | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (1) | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | Deposit date: | 2022-09-13 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EH9
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![BU of 8eh9 by Molmil](/molmil-images/mine/8eh9) | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (2) | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | Deposit date: | 2022-09-13 | Release date: | 2023-03-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1I
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![BU of 8f1i by Molmil](/molmil-images/mine/8f1i) | SigN RNA polymerase early-melted intermediate bound to mismatch fragment dhsU36mm1 (-12T) | Descriptor: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Mueller, A.U, Chen, J, Darst, S.A. | Deposit date: | 2022-11-05 | Release date: | 2023-04-05 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1J
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![BU of 8f1j by Molmil](/molmil-images/mine/8f1j) | SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A) | Descriptor: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Mueller, A.U, Chen, J, Darst, S.A. | Deposit date: | 2022-11-05 | Release date: | 2023-04-05 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1K
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![BU of 8f1k by Molmil](/molmil-images/mine/8f1k) | SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T) | Descriptor: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Mueller, A.U, Chen, J, Darst, S.A. | Deposit date: | 2022-11-05 | Release date: | 2023-04-05 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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4GZY
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![BU of 4gzy by Molmil](/molmil-images/mine/4gzy) | Crystal structures of bacterial RNA Polymerase paused elongation complexes | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A. | Deposit date: | 2012-09-06 | Release date: | 2013-02-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.5054 Å) | Cite: | Structural basis of transcriptional pausing in bacteria. Cell(Cambridge,Mass.), 152, 2013
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4GZZ
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![BU of 4gzz by Molmil](/molmil-images/mine/4gzz) | Crystal structures of bacterial RNA Polymerase paused elongation complexes | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A. | Deposit date: | 2012-09-06 | Release date: | 2013-02-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4.2927 Å) | Cite: | Structural basis of transcriptional pausing in bacteria. Cell(Cambridge,Mass.), 152, 2013
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4L5G
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![BU of 4l5g by Molmil](/molmil-images/mine/4l5g) | Crystal structure of Thermus thermophilus CarD | Descriptor: | CarD | Authors: | Srivastava, D.B, Westblade, L.F, Campbell, E.A, Darst, S.A. | Deposit date: | 2013-06-11 | Release date: | 2013-07-31 | Last modified: | 2013-08-21 | Method: | X-RAY DIFFRACTION (2.3902 Å) | Cite: | Structure and function of CarD, an essential mycobacterial transcription factor. Proc.Natl.Acad.Sci.USA, 110, 2013
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4L6Y
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![BU of 4l6y by Molmil](/molmil-images/mine/4l6y) | Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1) | Descriptor: | Protein regulator of cytokinesis 1 | Authors: | Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M. | Deposit date: | 2013-06-13 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3015 Å) | Cite: | Marking and Measuring Single Microtubules by PRC1 and Kinesin-4. Cell(Cambridge,Mass.), 154, 2013
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4L3I
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![BU of 4l3i by Molmil](/molmil-images/mine/4l3i) | Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1) | Descriptor: | Protein regulator of cytokinesis 1 | Authors: | Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M. | Deposit date: | 2013-06-06 | Release date: | 2013-07-17 | Last modified: | 2013-08-07 | Method: | X-RAY DIFFRACTION (3.6005 Å) | Cite: | Marking and Measuring Single Microtubules by PRC1 and Kinesin-4. Cell(Cambridge,Mass.), 154, 2013
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4XLS
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![BU of 4xls by Molmil](/molmil-images/mine/4xls) | |
4XAX
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![BU of 4xax by Molmil](/molmil-images/mine/4xax) | Crystal structure of Thermus thermophilus CarD in complex with the Thermus aquaticus RNA polymerase beta1 domain | Descriptor: | 1,2-ETHANEDIOL, CarD, DNA-directed RNA polymerase subunit beta domain 1 | Authors: | Chen, J, Bae, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2014-12-15 | Release date: | 2015-09-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.404 Å) | Cite: | CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
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