5XHI
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![BU of 5xhi by Molmil](/molmil-images/mine/5xhi) | Crystal structure of Frog M-ferritin D38A mutant | Descriptor: | CHLORIDE ION, Ferritin, middle subunit, ... | Authors: | Jagdev, M.K, Vasudevan, D. | Deposit date: | 2017-04-21 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104 Biochim. Biophys. Acta, 1865, 2017
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5XHO
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![BU of 5xho by Molmil](/molmil-images/mine/5xho) | Crystal structure of Frog M-ferritin E135K mutant | Descriptor: | CHLORIDE ION, Ferritin, middle subunit, ... | Authors: | Jagdev, M.K, Vasudevan, D. | Deposit date: | 2017-04-21 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104 Biochim. Biophys. Acta, 1865, 2017
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3LCA
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![BU of 3lca by Molmil](/molmil-images/mine/3lca) | |
1JBK
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![BU of 1jbk by Molmil](/molmil-images/mine/1jbk) | |
3KQI
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![BU of 3kqi by Molmil](/molmil-images/mine/3kqi) | crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide | Descriptor: | CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ... | Authors: | Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M. | Deposit date: | 2009-11-17 | Release date: | 2010-02-02 | Last modified: | 2019-02-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation. J.Biol.Chem., 285, 2010
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4QQF
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![BU of 4qqf by Molmil](/molmil-images/mine/4qqf) | |
3QFP
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![BU of 3qfp by Molmil](/molmil-images/mine/3qfp) | Crystal structure of yeast Hsp70 (Bip/Kar2) ATPase domain | Descriptor: | 78 kDa glucose-regulated protein homolog, PHOSPHATE ION | Authors: | Yan, M, Li, J.Z, Sha, B.D. | Deposit date: | 2011-01-22 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor. Biochem.J., 438, 2011
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3QML
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![BU of 3qml by Molmil](/molmil-images/mine/3qml) | The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as a novel nucleotide exchange factor | Descriptor: | 78 kDa glucose-regulated protein homolog, MAGNESIUM ION, Nucleotide exchange factor SIL1, ... | Authors: | Yan, M, Li, J.Z, Sha, B.D. | Deposit date: | 2011-02-04 | Release date: | 2011-06-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor. Biochem.J., 438, 2011
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3QFU
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![BU of 3qfu by Molmil](/molmil-images/mine/3qfu) | Crystal structure of Yeast Hsp70 (Bip/kar2) complexed with ADP | Descriptor: | 78 kDa glucose-regulated protein homolog, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Yan, M, Li, J.Z, Sha, B.D. | Deposit date: | 2011-01-22 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor. Biochem.J., 438, 2011
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3QLE
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![BU of 3qle by Molmil](/molmil-images/mine/3qle) | Structural Basis for the Function of Tim50 in the Mitochondrial Presequence Translocase | Descriptor: | ACETATE ION, CALCIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Qian, X.G, Gebert, M, Hpker, J, Yan, M, Li, J.Z, Wiedemann, N, Laan, M.V.D, Pfanner, N, Sha, B.D. | Deposit date: | 2011-02-02 | Release date: | 2011-03-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.831 Å) | Cite: | Structural basis for the function of tim50 in the mitochondrial presequence translocase. J.Mol.Biol., 411, 2011
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3QD2
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![BU of 3qd2 by Molmil](/molmil-images/mine/3qd2) | Crystal structure of mouse PERK kinase domain | Descriptor: | Eukaryotic translation initiation factor 2-alpha kinase 3 | Authors: | Wenjun, C, Jingzhi, L, David, R, Bingdong, S. | Deposit date: | 2011-01-17 | Release date: | 2011-04-27 | Last modified: | 2019-01-16 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | The structure of the PERK kinase domain suggests the mechanism for its activation. Acta Crystallogr.,Sect.D, 67, 2011
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6YVX
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![BU of 6yvx by Molmil](/molmil-images/mine/6yvx) | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic BB-287 | Descriptor: | 4-(isoquinolin-3-ylamino)-4-oxobutanoic acid, BICARBONATE ION, Egl nine homolog 1, ... | Authors: | Chowdhury, R, Banerji, B, Schofield, C.J. | Deposit date: | 2020-04-28 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
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3H42
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![BU of 3h42 by Molmil](/molmil-images/mine/3h42) | Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody | Descriptor: | Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ... | Authors: | Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E. | Deposit date: | 2009-04-17 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc.Natl.Acad.Sci.USA, 106, 2009
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6YW4
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![BU of 6yw4 by Molmil](/molmil-images/mine/6yw4) | |
6UUM
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![BU of 6uum by Molmil](/molmil-images/mine/6uum) | Crystal structure of antibody 438-B11 DSS mutant (Cys98A-Cys100aA) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, B11 DSS Fab Heavy Chain, ... | Authors: | Kumar, S, Wilson, I.A. | Deposit date: | 2019-10-30 | Release date: | 2020-09-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Sci Adv, 6, 2020
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6UUL
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![BU of 6uul by Molmil](/molmil-images/mine/6uul) | Crystal structure of broad and potent HIV-1 neutralizing antibody 438-D5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, D5 Fab Heavy Chain, ... | Authors: | Kumar, S, Wilson, I.A. | Deposit date: | 2019-10-30 | Release date: | 2020-09-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Sci Adv, 6, 2020
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6UTK
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![BU of 6utk by Molmil](/molmil-images/mine/6utk) | |
6UUH
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![BU of 6uuh by Molmil](/molmil-images/mine/6uuh) | |
6V6W
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5K0M
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![BU of 5k0m by Molmil](/molmil-images/mine/5k0m) | Targeting the PRC2 complex through a novel protein-protein interaction inhibitor of EED | Descriptor: | (3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}pyrrolidin-3-amine, Polycomb protein EED | Authors: | Jakob, C.G, Bigelow, L.J, Zhu, H, Sun, C. | Deposit date: | 2016-05-17 | Release date: | 2017-01-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat. Chem. Biol., 13, 2017
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5KJ2
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![BU of 5kj2 by Molmil](/molmil-images/mine/5kj2) | The novel p300/CBP inhibitor A-485 uncovers a unique mechanism of action to target AR in castrate resistant prostate cancer | Descriptor: | Histone acetyltransferase p300, N-[(4-fluorophenyl)methyl]-2-{(1R)-5-[(methylcarbamoyl)amino]-2',4'-dioxo-2,3-dihydro-3'H-spiro[indene-1,5'-[1,3]oxazolidin]-3'-yl}-N-[(2S)-1,1,1-trifluoropropan-2-yl]acetamide, SODIUM ION | Authors: | Jakob, C.G, Qiu, W, Edalji, R.P, Sun, C. | Deposit date: | 2016-06-17 | Release date: | 2017-09-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature, 550, 2017
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4UF1
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![BU of 4uf1 by Molmil](/molmil-images/mine/4uf1) | Deerpox virus DPV022 in complex with Bak BH3 | Descriptor: | Antiapoptotic membrane protein, Bcl-2 homologous antagonist/killer, SULFATE ION | Authors: | Burton, D.R, Kvansakul, M. | Deposit date: | 2014-12-23 | Release date: | 2015-08-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis. Acta Crystallogr.,Sect.D, 71, 2015
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4UF2
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![BU of 4uf2 by Molmil](/molmil-images/mine/4uf2) | Deerpox virus DPV022 in complex with Bax BH3 | Descriptor: | Antiapoptotic membrane protein, Apoptosis regulator BAX | Authors: | Burton, D.R, Kvansakul, M. | Deposit date: | 2014-12-23 | Release date: | 2015-08-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis. Acta Crystallogr.,Sect.D, 71, 2015
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4UF3
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![BU of 4uf3 by Molmil](/molmil-images/mine/4uf3) | Deerpox virus DPV022 in complex with Bim BH3 | Descriptor: | Antiapoptotic membrane protein, Bcl-2-like protein 11 | Authors: | Burton, D.R, Kvansakul, M. | Deposit date: | 2014-12-23 | Release date: | 2015-08-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis. Acta Crystallogr.,Sect.D, 71, 2015
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8CK2
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![BU of 8ck2 by Molmil](/molmil-images/mine/8ck2) | MUC2 CysD1 G1352S | Descriptor: | ACETATE ION, CALCIUM ION, Mucin-2, ... | Authors: | Khmelnitsky, L, Fass, D. | Deposit date: | 2023-02-14 | Release date: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Pulmonary Fibrosis Mutation Undermines Mucin 5B Supramolecular Assembly To Be Published
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