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Crystal structure of human Interleukin-1 receptor associated Kinase 4 (IRAK 4, CID 100300) in complex with compound NCC00371481 (BSI 107591)
Descriptor:	1,2-ETHANEDIOL, 6-[7-methoxy-6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-N-[(3R)-pyrrolidin-3-yl]pyridin-2-amine, Interleukin-1 receptor-associated kinase 4
Authors:	Abendroth, J, Mayclin, S.J, Lorimer, D.D, Starczynowski, D, Hoyt, S, Tawa, G, Thomas, C.
Deposit date:	2018-10-04
Release date:	2019-10-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Overcoming adaptive therapy resistance in AML by targeting immune response pathways. Sci Transl Med, 11, 2019

7RCR

Crystal Structure of the refolded Hemagglutinin head domain of Influenza A virus A/Ohio/09/2015
Descriptor:	1,2-ETHANEDIOL, Hemagglutinin
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-07-08
Release date:	2021-08-04
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Crystal Structure of the refolded Hemagglutinin head domain of Influenzavirus A Influenza A virus A/Ohio/09/2015 to be published

7RHE

Crystal Structure of ROK family protein from Burkholderia vietnamiensis G4
Descriptor:	ROK family protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-07-16
Release date:	2021-11-17
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal Structure of ROK family protein from Burkholderia vietnamiensis G4 to be published

7S5N

Crystal Structure of a Putative uncharacterized protein from Mycobacterium marinum
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, MymaA.17060.a, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-09-10
Release date:	2021-09-22
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Crystal Structure of a Putative uncharacterized protein from Mycobacterium marinum to be published

7S5E

Crystal structure of a guanylate kinase from Stenotrophomonas maltophilia K279a with heterogeneous ligand states of GMP/ADP, GMP/-, GDP/-, and GMP/ATPgS
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-09-10
Release date:	2021-09-22
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Crystal structure of a guanylate kinase from Stenotrophomonas maltophilia K279c with heterogeneous ligand states of GMP/ADP, GMP/-, GDP/-, and GMP/ATPgS. To Be Published

7S5M

Crystal Structure of a 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase from Mycobacterium smegmatis
Descriptor:	8-amino-7-oxononanoate synthase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-09-10
Release date:	2021-09-22
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Crystal Structure of a 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase from Mycobacterium smegmatis to be published

7RZM

Crystal Structure of dnaN DNA polymerase III beta subunit from Stenotrophomonas maltophilia K279a
Descriptor:	DNA polymerase III subunit beta
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-08-27
Release date:	2021-10-20
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Crystal Structure of dnaN DNA polymerase III beta subunit from Stenotrophomonas maltophilia K279a To Be Published

7SH3

Crystal Structure of a VirB8-like Protein of Type IV Secretion System from Rickettsia typhi in Complex with a Synthetic VirB8 Miniprotein Binder
Descriptor:	Synthetic VirB8 Miniprotein Binder, VirB8-like protein of type IV secretion system
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-07
Release date:	2021-10-20
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Crystal Structure of a VirB8-like Protein of Type IV Secretion System from Rickettsia typhi in Complex with a Synthetic VirB8 Miniprotein Binder to be published

7RZO

Crystal structure of a dihydrofolate reductase (folA) from Stenotrophomonas maltophilia
Descriptor:	1,2-ETHANEDIOL, CHLORIDE ION, Dihydrofolate reductase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-08-27
Release date:	2021-10-20
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal Structure of dihydrofolate reductase from Stenotrophomonas maltophilia K279a to be published

7RY7

Structure of Plasmepsin X (PM10, PMX) from Plasmodium falciparum 3D7
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasmepsin X
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-08-24
Release date:	2022-02-02
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme. Protein Sci., 31, 2022

6P81

Structure of DNA polymerase III, beta subunit/ beta sliding clamp from Klebsiella pneumoniae, expressed with an N-terminal His-Smt3 fusion tag, in complex with Griselimycin
Descriptor:	1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ACETATE ION, CALCIUM ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-06-06
Release date:	2019-07-10
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Structure of DNA polymerase III, beta subunit/ beta sliding clamp from Klebsiella pneumoniae, expressed with an N-terminal His-Smt3 fusion tag, in complex with Griselimycin to be published

6PBL

Crystal structure of Malate dehydrogenase from Legionella pneumophila Philadelphia 1
Descriptor:	Malate dehydrogenase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-06-14
Release date:	2019-07-24
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Crystal structure of Malate dehydrogenase from Legionella pneumophila Philadelphia 1 TO BE PUBLISHED

6PTR

Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Bartonella birtlesii bound to griselimycin
Descriptor:	1,2-ETHANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-07-16
Release date:	2019-08-07
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Bartonella birtlesii bound to griselimycin To Be Published

6Q1Y

Crystal Structure of Enoyl-[acyl-carrier-protein] reductase from Mycobacterium avium with bound NAD
Descriptor:	1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-08-06
Release date:	2019-08-14
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Crystal Structure of Enoyl-[acyl-carrier-protein] reductase from Mycobacterium avium with bound NAD to be published

6PTG

Structure of RNA polymerase binding protein and transcriptional regulator Dks from Chlamydia trachomatis L2 (LGV434)
Descriptor:	DnaK Suppressor
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-07-15
Release date:	2019-07-24
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.95 Å)
Cite:	Structure of RNA polymerase binding protein and transcriptional regulator Dks from Chlamydia trachomatis L2 (LGV434) to be published

6Q10

Crystal structure of the soluble domain (residues 71-217) of a conserved hypothetical secreted protein (Rv2700 ortholog) from Mycobacterium marinum
Descriptor:	1,2-ETHANEDIOL, MymaA.19257.a.B3
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-08-02
Release date:	2019-08-14
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	SSGCID, Mycobacerium marinum, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, secreted protein, Rv2700 ortholog to be published

6PTV

Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-07-16
Release date:	2019-08-07
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin To Be Published

6PTH

Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Pseudomonas aeruginosa bound to griselimycin
Descriptor:	Beta sliding clamp, Griselimycin, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-07-15
Release date:	2019-08-07
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (3.05 Å)
Cite:	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Pseudomonas aeruginosa bound to griselimycin To Be Published

4RGB

Crystal structure of a putative carveol dehydrogenase from Mycobacterium avium bound to NAD
Descriptor:	Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2014-09-29
Release date:	2014-10-15
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017

3I3R

X-ray structure dihydrofolate reductase/thymidylate synthase from babesia bovis at 2.35A resolution
Descriptor:	CHLORIDE ION, Dihydrofolate reductase/thymidylate synthase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2009-06-30
Release date:	2009-08-18
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.35 Å)
Cite:	Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallogr.,Sect.F, 67, 2011

3K2H

Co-crystal structure of dihydrofolate reductase/thymidylate synthase from Babesia bovis with dUMP, Pemetrexed and NADP
Descriptor:	1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2009-09-30
Release date:	2009-10-13
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallogr.,Sect.F, 67, 2011

3MEB

Structure of cytoplasmic aspartate aminotransferase from giardia lamblia
Descriptor:	1,2-ETHANEDIOL, Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-03-31
Release date:	2010-04-21
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015

8D1X

Crystal Structure of aminopeptidase A from Neisseria gonorrhoeae
Descriptor:	ACETATE ION, CHLORIDE ION, D(-)-TARTARIC ACID, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-05-27
Release date:	2022-06-08
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Crystal Structure of aminopeptidase A from Neisseria gonorrhoeae to be published

8D57

Crystal Structure of dihydrodipicolinate reductase from Acinetobacter baumannii
Descriptor:	4-hydroxy-tetrahydrodipicolinate reductase, CITRIC ACID
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-06-04
Release date:	2022-06-22
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Crystal Structure of dihydrodipicolinate reductase from Acinetobacter baumannii to be published

8D2Z

Crystal Structure of a Metallo-beta-lactamase superfamily protein from Burkholderia cenocepacia
Descriptor:	(4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-05-31
Release date:	2023-07-05
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Crystal Structure of a Metallo-beta-lactamase superfamily protein from Burkholderia cenocepacia to be published

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Displayed results:	25
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