1L9A
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![BU of 1l9a by Molmil](/molmil-images/mine/1l9a) | CRYSTAL STRUCTURE OF SRP19 IN COMPLEX WITH THE S DOMAIN OF SIGNAL RECOGNITION PARTICLE RNA | Descriptor: | MAGNESIUM ION, METHYL MERCURY ION, SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN, ... | Authors: | Oubridge, C, Kuglstatter, A, Jovine, L, Nagai, K. | Deposit date: | 2002-03-22 | Release date: | 2002-06-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle. Mol.Cell, 9, 2002
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2WS0
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![BU of 2ws0 by Molmil](/molmil-images/mine/2ws0) | Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5 | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-03 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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4PSF
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![BU of 4psf by Molmil](/molmil-images/mine/4psf) | PIH1D1 N-terminal domain | Descriptor: | PIH1 domain-containing protein 1 | Authors: | Smerdon, S.J, Boulton, S.J, Stach, L, Flower, T.G, Horejsi, Z. | Deposit date: | 2014-03-07 | Release date: | 2014-04-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.578 Å) | Cite: | Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex. Cell Rep, 7, 2014
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4PTF
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![BU of 4ptf by Molmil](/molmil-images/mine/4ptf) | Ternary crystal structure of yeast DNA polymerase epsilon with template G | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', ... | Authors: | Jain, R, Rajashankar, K.R, Buku, A, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2014-03-10 | Release date: | 2014-04-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.809 Å) | Cite: | Crystal Structure of Yeast DNA Polymerase epsilon Catalytic Domain. Plos One, 9, 2014
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4PJR
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![BU of 4pjr by Molmil](/molmil-images/mine/4pjr) | Crystal structure of designed cPPR-NRE protein | Descriptor: | MAGNESIUM ION, Pentatricopeptide repeat protein | Authors: | Coquille, S.C, Filipovska, A, Chia, T.S, Rajappa, L, Lingford, J.P, Razif, M.F.M, Thore, S, Rackham, O. | Deposit date: | 2014-05-12 | Release date: | 2014-12-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | An artificial PPR scaffold for programmable RNA recognition. Nat Commun, 5, 2014
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2V35
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![BU of 2v35 by Molmil](/molmil-images/mine/2v35) | Porcine Pancreatic Elastase in complex with inhibitor JM54 | Descriptor: | (2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACID, ELASTASE-1, GLYCEROL, ... | Authors: | Oliveira, T.F, Mulchande, J, Martins, L, Moreira, R, Iley, J, Archer, M. | Deposit date: | 2007-06-12 | Release date: | 2008-06-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | The Efficiency of C-4 Substituents in Activating the Beta-Lactam Scaffold Towards Serine Proteases and Hydroxide Ion. Org.Biomol.Chem., 5, 2007
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4PRS
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![BU of 4prs by Molmil](/molmil-images/mine/4prs) | Structure of apo ArgBP from T. maritima | Descriptor: | ABC-type transporter, periplasmic subunit family 3 | Authors: | Ruggiero, A, Dattelbaum, J.D, Staiano, M, Berisio, R, D'Auria, S, Vitagliano, L. | Deposit date: | 2014-03-06 | Release date: | 2014-07-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima Plos One, 9, 2014
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5G4V
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4PUP
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![BU of 4pup by Molmil](/molmil-images/mine/4pup) | 2.75 Angstrom resolution crystal structure of uncharacterized protein from Burkholderia cenocepacia J2315 | Descriptor: | Uncharacterized protein | Authors: | Halavaty, A.S, Filippova, E.V, Wawrzak, Z, Kiryukhina, O, Minasov, G, Jedrzejczak, R, Shuvalova, L, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-03-13 | Release date: | 2014-04-16 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | 2.75 Angstrom resolution crystal structure of uncharacterized protein from Burkholderia cenocepacia J2315 To be Published
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2UV4
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![BU of 2uv4 by Molmil](/molmil-images/mine/2uv4) | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | Descriptor: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE | Authors: | Day, P, Sharff, A, PArra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | Deposit date: | 2007-03-09 | Release date: | 2007-05-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp. Acta Crystallogr.,Sect.D, 63, 2007
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1KZI
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![BU of 1kzi by Molmil](/molmil-images/mine/1kzi) | Crystal Structure of EcTS/dUMP/THF Complex | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (6S)-5,6,7,8-TETRAHYDROFOLATE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ... | Authors: | Fritz, T.A, Liu, L, Finer-Moore, J.S, Stroud, R.M. | Deposit date: | 2002-02-06 | Release date: | 2002-07-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Tryptophan 80 and leucine 143 are critical for the hydride transfer step of thymidylate synthase by controlling active site access. Biochemistry, 41, 2002
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4PGA
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![BU of 4pga by Molmil](/molmil-images/mine/4pga) | GLUTAMINASE-ASPARAGINASE FROM PSEUDOMONAS 7A | Descriptor: | AMMONIUM ION, GLUTAMINASE-ASPARAGINASE, SULFATE ION | Authors: | Jakob, C.G, Lewinski, K, Lacount, M.W, Roberts, J, Lebioda, L. | Deposit date: | 1997-01-14 | Release date: | 1997-07-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Ion binding induces closed conformation in Pseudomonas 7A glutaminase-asparaginase (PGA): crystal structure of the PGA-SO4(2-)-NH4+ complex at 1.7 A resolution. Biochemistry, 36, 1997
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1LB1
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![BU of 1lb1 by Molmil](/molmil-images/mine/1lb1) | Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA | Descriptor: | Guanine nucleotide exchange factor DBS, Transforming protein RhoA | Authors: | Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J. | Deposit date: | 2002-04-01 | Release date: | 2002-05-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9, 2002
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5GIB
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![BU of 5gib by Molmil](/molmil-images/mine/5gib) | Succinic acid bound trypsin crystallized as dimer | Descriptor: | CALCIUM ION, Cationic trypsin, SUCCINIC ACID | Authors: | Kutumbarao, N.H.V, Manohar, R, KarthiK, L, Malathy, P, Gunasekaran, K, Velmurugan, D. | Deposit date: | 2016-06-22 | Release date: | 2016-08-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.697 Å) | Cite: | Trypsin bound with Succinic acid To Be Published
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2UZ3
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![BU of 2uz3 by Molmil](/molmil-images/mine/2uz3) | Crystal Structure of Thymidine Kinase with dTTP from U. urealyticum | Descriptor: | MAGNESIUM ION, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ... | Authors: | Welin, M, Kosinska, U, Mikkelsen, N.E, Carnrot, C, Zhu, C, Wang, L, Eriksson, S, Munch-Petersen, B, Eklund, H. | Deposit date: | 2007-04-24 | Release date: | 2007-05-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of Thymidine Kinase 1 of Human and Mycoplasmic Origin Proc.Natl.Acad.Sci.USA, 101, 2004
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2VKJ
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![BU of 2vkj by Molmil](/molmil-images/mine/2vkj) | Structure of the soluble domain of the membrane protein TM1634 from Thermotoga maritima | Descriptor: | SULFATE ION, TM1634 | Authors: | McCleverty, C.J, Columbus, L, Kreusch, A, Lesley, S.A, Joint Center for Structural Genomics (JCSG) | Deposit date: | 2007-12-19 | Release date: | 2008-04-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure and Ligand Binding of the Soluble Domain of a Thermotoga Maritima Membrane Protein of Unknown Function Tm1634. Protein Sci., 17, 2008
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1L3W
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![BU of 1l3w by Molmil](/molmil-images/mine/1l3w) | C-cadherin Ectodomain | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Boggon, T.J, Murray, J, Chappuis-Flament, S, Wong, E, Gumbiner, B.M, Shapiro, L. | Deposit date: | 2002-03-01 | Release date: | 2002-04-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.08 Å) | Cite: | C-cadherin ectodomain structure and implications for cell adhesion mechanisms Science, 296, 2002
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2UVP
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![BU of 2uvp by Molmil](/molmil-images/mine/2uvp) | Crystal structure of HobA (HP1230)from Helicobacter pylori | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Terradot, L, Natrajan, G, Thompson, A.C, Hall, D.R. | Deposit date: | 2007-03-13 | Release date: | 2007-08-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural similarity between the DnaA-binding proteins HobA (HP1230) from Helicobacter pylori and DiaA from Escherichia coli. Mol. Microbiol., 65, 2007
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4PWL
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![BU of 4pwl by Molmil](/molmil-images/mine/4pwl) | Crystal structure of the complex between PPARgamma-LBD and the S enantiomer of Mbx-102 (Metaglidasen) | Descriptor: | (2S)-(4-chlorophenyl)[3-(trifluoromethyl)phenoxy]ethanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Pochetti, G, Montanari, R, Capelli, D, Loiodice, F, Laghezza, A, Lavecchia, A, Piemontese, L. | Deposit date: | 2014-03-20 | Release date: | 2015-02-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles. Chemmedchem, 10, 2015
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2UV5
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![BU of 2uv5 by Molmil](/molmil-images/mine/2uv5) | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | Descriptor: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | Authors: | Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | Deposit date: | 2007-03-09 | Release date: | 2007-05-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp. Acta Crystallogr.,Sect.D, 63, 2007
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5GKW
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![BU of 5gkw by Molmil](/molmil-images/mine/5gkw) | crystal structure of SZ529 complex with (R,R)-cyclopentanediol | Descriptor: | (1~{R},2~{R})-cyclopentane-1,2-diol, Limonene-1,2-epoxide hydrolase | Authors: | Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H. | Deposit date: | 2016-07-07 | Release date: | 2017-07-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | crystal structure of SZ529 complex with (R,R)-cyclopentanediol To Be Published
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1JIX
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![BU of 1jix by Molmil](/molmil-images/mine/1jix) | T4 Phage BGT in Complex with Ca2+ | Descriptor: | CALCIUM ION, DNA BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | Authors: | Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W. | Deposit date: | 2001-07-03 | Release date: | 2001-08-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding. J.Mol.Biol., 311, 2001
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2UV7
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![BU of 2uv7 by Molmil](/molmil-images/mine/2uv7) | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | Descriptor: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE | Authors: | Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | Deposit date: | 2007-03-09 | Release date: | 2007-05-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp. Acta Crystallogr.,Sect.D, 63, 2007
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4PY0
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![BU of 4py0 by Molmil](/molmil-images/mine/4py0) | Crystal structure of P2Y12 receptor in complex with 2MeSATP | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), P2Y purinoceptor 12, ... | Authors: | Zhang, J, Zhang, K, Gao, Z.G, Paoletta, S, Zhang, D, Han, G.W, Li, T, Ma, L, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR) | Deposit date: | 2014-03-25 | Release date: | 2014-04-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Agonist-bound structure of the human P2Y12 receptor Nature, 509, 2014
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2VEP
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![BU of 2vep by Molmil](/molmil-images/mine/2vep) | Crystal Structure Of The Full Length Bifunctional Enzyme Pria | Descriptor: | PHOSPHORIBOSYL ISOMERASE A, SULFATE ION | Authors: | Wright, H, Noda-Garcia, L, Ochoa-Leyva, A, Hodgson, D.A, Fulop, V, Barona-Gomez, F. | Deposit date: | 2007-10-25 | Release date: | 2007-11-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure/Function Relationship of a Dual Substrate (Betaalpha)(8)-Isomerase Biochem.Biophys.Res.Commun., 365, 2008
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