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1L70
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BU of 1l70 by Molmil
MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Zhang, X, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein Sci., 1, 1992
1L75
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BU of 1l75 by Molmil
MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Zhang, X, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2020-07-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein Sci., 1, 1992
7VOH
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BU of 7voh by Molmil
The a-glucosidase QsGH13 from Qipengyuania seohaensis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, alpha-glucosidase QsGH13
Authors:Huang, J, Zhai, X.Y.
Deposit date:2021-10-13
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Structure and Function Insight of the alpha-Glucosidase QsGH13 From Qipengyuania seohaensis sp. SW-135.
Front Microbiol, 13, 2022
1MCY
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BU of 1mcy by Molmil
SPERM WHALE MYOGLOBIN (MUTANT WITH INITIATOR MET AND WITH HIS 64 REPLACED BY GLN, LEU 29 REPLACED BY PHE
Descriptor: CARBON MONOXIDE, MYOGLOBIN (CARBONMONOXY), PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, T, Phillips Jr, G.N.
Deposit date:1995-07-19
Release date:1995-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A double mutant of sperm whale myoglobin mimics the structure and function of elephant myoglobin.
J.Biol.Chem., 270, 1995
5TD4
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BU of 5td4 by Molmil
Starch binding sites on the Human pancreatic alpha amylase D300N variant complexed with an octaose substrate.
Descriptor: CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ...
Authors:Caner, S, Brayer, G.D.
Deposit date:2016-09-16
Release date:2016-11-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evaluation of the Significance of Starch Surface Binding Sites on Human Pancreatic alpha-Amylase.
Biochemistry, 55, 2016
2CCD
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BU of 2ccd by Molmil
Crystal structure of the catalase-peroxidase (KatG) and S315T mutant from Mycobacterium tuberculosis
Descriptor: PEROXIDASE/CATALASE T, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yu, H, Sacchettini, J.C.
Deposit date:2006-01-16
Release date:2006-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Hydrogen Peroxide-Mediated Isoniazid Activation Catalyzed by Mycobacterium Tuberculosis Catalase- Peroxidase (Katg) and its S315T Mutant.
Biochemistry, 45, 2006
2CCA
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BU of 2cca by Molmil
Crystal structure of the catalase-peroxidase (KatG) and S315T mutant from Mycobacterium tuberculosis
Descriptor: PEROXIDASE/CATALASE T, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yu, H, Sacchettini, J.C.
Deposit date:2006-01-16
Release date:2006-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrogen Peroxide-Mediated Isoniazid Activation Catalyzed by Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) and its S315T Mutant.
Biochemistry, 45, 2006
7Y9O
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BU of 7y9o by Molmil
Crystal structure of a CYP109B4 variant from Bacillus sonorensis
Descriptor: CALCIUM ION, Cytochrome P450 monooxygenase YjiB, IMIDAZOLE, ...
Authors:Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T.
Deposit date:2022-06-25
Release date:2023-05-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023
7Y97
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BU of 7y97 by Molmil
Crystal structure of CYP109B4 from Bacillus Sonorensis
Descriptor: Cytochrome P450 monooxygenase YjiB, PROTOPORPHYRIN IX CONTAINING FE
Authors:Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T.
Deposit date:2022-06-24
Release date:2023-05-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023
7Y98
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BU of 7y98 by Molmil
Crystal structure of CYP109B4 from Bacillus Sonorensis in complex with Testosterone
Descriptor: Cytochrome P450 monooxygenase YjiB, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE
Authors:Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T.
Deposit date:2022-06-24
Release date:2023-05-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023
3NTZ
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BU of 3ntz by Molmil
Design, Synthesis, Biological Evaluation and X-ray Crystal Structures of Novel Classical 6,5,6-tricyclicbenzo[4,5]thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors
Descriptor: Dihydrofolate reductase, N-[(4-{[(2-amino-4-oxo-3,4-dihydro[1]benzothieno[2,3-d]pyrimidin-5-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Cody, V.
Deposit date:2010-07-06
Release date:2011-05-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.
Bioorg.Med.Chem., 19, 2011
3NU0
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BU of 3nu0 by Molmil
Design, Synthesis, Biological Evaluation and X-ray Crystal Structure of Novel Classical 6,5,6-TricyclicBenzo[4,5]thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors
Descriptor: (2S)-2-(5-{[(2-amino-4-oxo-3,4-dihydro[1]benzothieno[2,3-d]pyrimidin-5-yl)methyl]amino}-1-oxo-1,3-dihydro-2H-isoindol-2-yl)pentanedioic acid, Dihydrofolate reducatase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Cody, V.
Deposit date:2010-07-06
Release date:2011-05-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.
Bioorg.Med.Chem., 19, 2011
3J8D
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BU of 3j8d by Molmil
Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5
Descriptor: Envelope protein E, antibody E111 Fab fragment, glycoprotein DIII
Authors:Zhang, X.Z, Sheng, J, Austin, S.K, Hoornweg, T, Smit, J.M, Kuhn, R.J, Diamond, M.S, Rossmann, M.G.
Deposit date:2014-10-13
Release date:2014-11-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (26 Å)
Cite:Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers.
J.Virol., 89, 2015
3J26
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BU of 3j26 by Molmil
The 3.5 A resolution structure of the Sputnik virophage by cryo-EM
Descriptor: Minor virion protein, capsid protein V20
Authors:Zhang, X.Z.
Deposit date:2012-09-18
Release date:2012-10-24
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of Sputnik, a virophage, at 3.5-A resolution.
Proc.Natl.Acad.Sci.USA, 109, 2012
3J35
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BU of 3j35 by Molmil
Cryo-EM reconstruction of Dengue virus at 37 C
Descriptor: envelope protein
Authors:Zhang, X.Z, Sheng, J, Plevka, P, Kuhn, R.J, Diamond, M.S, Rossmann, M.G.
Deposit date:2013-02-24
Release date:2013-04-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Dengue structure differs at the temperatures of its human and mosquito hosts.
Proc.Natl.Acad.Sci.USA, 110, 2013
4ISI
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BU of 4isi by Molmil
Structure of FACTOR VIIA in complex with the inhibitor (6S)-N-(4-CARBAMIMIDOYLBENZYL)-1-CHLORO-3-(CYCLOBUTYLAMINO)-8,8-DIETHYL-4-OXO-4,6,7,8-TETRAHYDROPYRROLO[1,2-A]PYRAZINE-6-CARBOXAMIDE
Descriptor: (6S)-N-(4-carbamimidoylbenzyl)-1-chloro-3-(cyclobutylamino)-8,8-diethyl-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide, CALCIUM ION, Factor VII heavy chain, ...
Authors:Wei, A.
Deposit date:2013-01-16
Release date:2013-02-27
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
7YOB
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BU of 7yob by Molmil
Crystal structure of Aldehyde dehydrogenase 1A1 from mouse
Descriptor: Aldehyde dehydrogenase 1A1
Authors:Zhang, X.Y, Ouyang, Z.Q.
Deposit date:2022-08-01
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Crystal structure of aldehyde dehydrogenase 1A1 from mouse.
Biochem.Biophys.Res.Commun., 628, 2022
7Y7D
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BU of 7y7d by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7C
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BU of 7y7c by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(G34) and mRNA(GAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7F
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BU of 7y7f by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAC)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7E
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BU of 7y7e by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7G
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BU of 7y7g by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7H
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BU of 7y7h by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
5ZCX
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BU of 5zcx by Molmil
Structure of T20/N39
Descriptor: Envelope glycoprotein, Envelope glycoprotein gp160
Authors:Zhang, X.J, Ding, X.H.
Deposit date:2018-02-21
Release date:2018-10-10
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Structural and functional characterization of HIV-1 cell fusion inhibitor T20.
AIDS, 33, 2019
4NGA
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BU of 4nga by Molmil
Factor viia in complex with the inhibitor (2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-N-[2-(propan-2-ylsulfonyl)benzyl]ethanamide
Descriptor: (2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-N-[2-(propan-2-ylsulfonyl)benzyl]ethanamide, CALCIUM ION, Factor VIIa (Heavy Chain), ...
Authors:Wei, A, Anumula, R.
Deposit date:2013-11-01
Release date:2014-01-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors.
ACS Med Chem Lett, 5, 2014

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數據於2024-09-04公開中

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