6LQE
 
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6LQF
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8ZG2
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8ZG3
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4U0Q
 | | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to basigin | | Descriptor: | Basigin, Reticulocyte binding protein 5 | | Authors: | Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. | | Deposit date: | 2014-07-14 | | Release date: | 2014-08-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature, 515, 2014
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6YEK
 | | Crystal structure of human NEMO apo form | | Descriptor: | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b | | Authors: | Garcia-Pardo, J, Akutsu, M, Busse, P, Skenderovic, A, Maculins, T, Dikic, I. | | Deposit date: | 2020-03-25 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.
Cell Chem Biol, 27, 2020
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4U13
 | | Crystal structure of putative polyketide cyclase (protein SMa1630) from Sinorhizobium meliloti at 2.3 A resolution | | Descriptor: | putative polyketide cyclase SMa1630 | | Authors: | Shabalin, I.G, Bacal, P, Osinski, T, Cooper, D.R, Szlachta, K, Stead, M, Grabowski, M, Hammonds, J, Ahmed, M, Hillerich, B.S, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2014-07-14 | | Release date: | 2014-09-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of a putative polyketide cyclase (protein SMa1630) from Sinorhizobium meliloti at 2.3 A resolution
to be published
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8ZM7
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4U25
 | | Crystal structure of the E. coli ribosome bound to virginiamycin M1. | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | | Deposit date: | 2014-07-16 | | Release date: | 2014-07-30 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
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8ZCI
 | | X-ray structure of the human heart fatty acid-binding protein complexed with R-Ibuprofen | | Descriptor: | (2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid, ACETIC ACID, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Sugiyama, S, Tanaka, J, Matsuoka, S, Murata, M. | | Deposit date: | 2024-04-29 | | Release date: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | X-ray structure of the human heart fatty acid-binding protein complexed with R-Ibuprofen
To Be Published
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8ZG4
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8ZYM
 | | Complex structure of 60 Fab bound to DS2 prefusion F trimer | | Descriptor: | Fusion glycoprotein F0,Expression tag, antibody light chain, antidody heavy chain | | Authors: | Wang, X, Ge, J, Guo, F. | | Deposit date: | 2024-06-18 | | Release date: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | DS2 designer pre-fusion F vaccine induces strong and protective antibody response against RSV infection.
Npj Vaccines, 9, 2024
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8ZI5
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8ZP3
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8ZLG
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8ZNU
 | | Catalytic antibody T99_C220A_dP95 | | Descriptor: | 1,2-ETHANEDIOL, CACODYLIC ACID, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Kobayashi, J, Yoshida, H, Tsuyuguchi, M, Kato, R. | | Deposit date: | 2024-05-28 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and biochemical differences between non-catalytic and catalytic antibodies.
Mabs, 17, 2025
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8ZMP
 | | Cryo-EM structure of the spike glycoprotein from Bat SARS-like coronavirus (Bat SL-CoV) WIV1 in locked state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | Authors: | Liu, C, Beck, F, Nagy, I, Bohn, S, Plitzko, J, Baumeister, W, Zhang, X, Zinzula, L. | | Deposit date: | 2024-05-23 | | Release date: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Cryo-EM structure of the spike glycoprotein from Bat SARS-like coronavirus WIV1
To Be Published
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8ZNT
 | | Catalytic antibody T99_C220A | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Catalytic antibody T99_C220A, ... | | Authors: | Kobayashi, J, Yoshida, H, Tsuyuguchi, M, Kato, R. | | Deposit date: | 2024-05-28 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Structural and biochemical differences between non-catalytic and catalytic antibodies.
Mabs, 17, 2025
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8ZQ7
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6YGN
 | | Titin kinase and its flanking domains | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Titin | | Authors: | Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O. | | Deposit date: | 2020-03-27 | | Release date: | 2021-04-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
Embo Rep., 22, 2021
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6YM5
 | | Crystal structure of BAY-091 with PIP4K2A | | Descriptor: | (2~{R})-2-[[3-cyano-2-[4-(2-fluoranyl-3-methyl-phenyl)phenyl]-1,7-naphthyridin-4-yl]amino]butanoic acid, PHOSPHATE ION, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | | Authors: | Holton, S.J, Wortmann, L, Braeuer, N, Irlbacher, H, Weiske, J, Lechner, C, Meier, R, Puetter, V, Christ, C, ter Laak, T, Lienau, P, Lesche, R, Nicke, B, Bauser, M, Haegebarth, A, von Nussbaum, F, Mumberg, D, Lemos, C. | | Deposit date: | 2020-04-07 | | Release date: | 2021-04-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A.
J.Med.Chem., 64, 2021
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4U1V
 | | Crystal structure of the E. coli ribosome bound to linopristin. | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | | Deposit date: | 2014-07-16 | | Release date: | 2014-07-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
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8ZSE
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8ZXB
 | | Structure of aminotransferase from Mycolicibacterium neoaurum in complex with PLP | | Descriptor: | Branched-chain amino acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Wei, H, Cong, L, Wang, J, You, S, Liu, W. | | Deposit date: | 2024-06-14 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure of aminotransferase from Mycolicibacterium neoaurum in complex with PLP
To Be Published
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6YN2
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