8ZM7

Engineering omega-amine transaminase for extending substrate scope by ancestral sequence reconstruction

Summary for 8ZM7

• Entry DOI: 10.2210/pdb8zm7/pdb
• Descriptor: Amine transaminase, SODIUM ION, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: homotetramer, plp-dependent enzyme, transferase
• Biological source: Aspergillus terreus
• Total number of polymer chains: 4
• Total formula weight: 150370.66

Authors

Huang, J.,Li, N.,Cai, T. (deposition date: 2024-05-22, release date: 2025-05-14, Last modification date: 2025-12-03)

• Primary citation: Cai, T.,Chen, J.,Wang, L.,Fan, F.,Chen, G.,Qiu, S.,Li, N.,Mei, L.,Huang, J.; Extending the Substrate Scope of an omega-Amine Transaminase from Aspergillus terreus by Reconstructing and Engineering an Ancestral Enzyme; Acs Catalysis, 15:7429-7440, 2025; DOI: 10.1021/acscatal.5c01779

Experimental method

X-RAY DIFFRACTION (2.3 Å)