7D2I
 
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with a Fe ion bound to the active site | | Descriptor: | FE (III) ION, Glutaminyl-peptide cyclotransferase, SULFATE ION | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-16 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D23
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with one K ion bound to the active site | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutaminyl-peptide cyclotransferase, POTASSIUM ION | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-15 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D17
 | | Crystal structure of Macrostomum lignano glutaminyl cyclase | | Descriptor: | Glutaminyl-peptide cyclotransferase, ZINC ION | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-14 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.998 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1Y
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with two Co ions bound to the active site | | Descriptor: | COBALT (II) ION, Glutaminyl-peptide cyclotransferase | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-15 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1N
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with three Cu ions bound to the active site | | Descriptor: | BICARBONATE ION, COPPER (II) ION, Glutaminyl-peptide cyclotransferase | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-15 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1P
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with three Cd ions bound to the active site | | Descriptor: | BICARBONATE ION, CADMIUM ION, Glutaminyl-peptide cyclotransferase | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-15 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D21
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with two Zn ions bound to the active site | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Glutaminyl-peptide cyclotransferase, ZINC ION | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-15 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1E
 | | Crystal structure of Bacteroides thetaiotaomicron glutaminyl cyclase bound to N-acetylhistamine | | Descriptor: | Leucine aminopeptidase, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE, ZINC ION | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-14 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1B
 | | Crystal structure of Fimbriiglobus ruber glutaminyl cyclase | | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CHLORIDE ION, GLYCEROL, ... | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-14 | | Release date: | 2021-04-14 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1H
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with D238A mutation | | Descriptor: | Glutaminyl-peptide cyclotransferase, ZINC ION | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-14 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D2J
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with a Cd ion bound to the active site | | Descriptor: | BICARBONATE ION, CADMIUM ION, Glutaminyl-peptide cyclotransferase | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-16 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D18
 | | Crystal structure of Acidobacteriales bacterium glutaminyl cyclase | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Peptidase M28, ... | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-14 | | Release date: | 2021-04-14 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.332 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D2D
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with a Mn ion bound to the active site | | Descriptor: | Glutaminyl-peptide cyclotransferase, MANGANESE (II) ION | | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | Deposit date: | 2020-09-16 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7DOH
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1D22
 | | BINDING OF THE ANTITUMOR DRUG NOGALAMYCIN AND ITS DERIVATIVES TO DNA: STRUCTURAL COMPARISON | | Descriptor: | DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3'), U-58872, HYDROXY DERIVATIVE OF NOGALAMYCIN | | Authors: | Gao, Y.-G, Liaw, Y.-C, Robinson, H, Wang, A.H.-J. | | Deposit date: | 1990-08-08 | | Release date: | 1991-07-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison.
Biochemistry, 29, 1990
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1VQB
 | | GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN) | | Descriptor: | GENE V PROTEIN | | Authors: | Skinner, M.M, Zhang, H, Leschnitzer, D.H, Guan, Y, Bellamy, H, Sweet, R.M, Gray, C.W, Konings, R.N.H, Wang, A.H.-J, Terwilliger, T.C. | | Deposit date: | 1996-08-14 | | Release date: | 1997-02-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein.
Proc.Natl.Acad.Sci.USA, 91, 1994
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1D21
 | | BINDING OF THE ANTITUMOR DRUG NOGALAMYCIN AND ITS DERIVATIVES TO DNA: STRUCTURAL COMPARISON | | Descriptor: | DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3'), NOGALAMYCIN | | Authors: | Gao, Y.-G, Liaw, Y.-C, Robinson, H, Wang, A.H.-J. | | Deposit date: | 1990-08-08 | | Release date: | 1991-07-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison.
Biochemistry, 29, 1990
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1YHB
 | | CRYSTAL STRUCTURES OF Y41H AND Y41F MUTANTS OF GENE V PROTEIN FROM FF PHAGE SUGGEST POSSIBLE PROTEIN-PROTEIN INTERACTIONS IN GVP-SSDNA COMPLEX | | Descriptor: | GENE V PROTEIN | | Authors: | Guan, Y, Zhang, H, Konings, R.N.H, Hilbers, C.W, Terwilliger, T.C, Wang, A.H.-J. | | Deposit date: | 1994-04-14 | | Release date: | 1994-06-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of Y41H and Y41F mutants of gene V protein from Ff phage suggest possible protein-protein interactions in the GVP-ssDNA complex.
Biochemistry, 33, 1994
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1YHA
 | | CRYSTAL STRUCTURES OF Y41H AND Y41F MUTANTS OF GENE V PROTEIN FROM FF PHAGE SUGGEST POSSIBLE PROTEIN-PROTEIN INTERACTIONS IN GVP-SSDNA COMPLEX | | Descriptor: | GENE V PROTEIN | | Authors: | Guan, Y, Zhang, H, Konings, R.N.H, Hilbers, C.W, Terwilliger, T.C, Wang, A.H.-J. | | Deposit date: | 1994-04-14 | | Release date: | 1994-06-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of Y41H and Y41F mutants of gene V protein from Ff phage suggest possible protein-protein interactions in the GVP-ssDNA complex.
Biochemistry, 33, 1994
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3ACW
 | | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-651 | | Descriptor: | (3R)-3-biphenyl-4-yl-1-azabicyclo[2.2.2]octan-3-ol, Dehydrosqualene synthase | | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E. | | Deposit date: | 2010-01-13 | | Release date: | 2010-11-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
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3ACX
 | | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673 | | Descriptor: | Dehydrosqualene synthase, N-(1-methylethyl)-3-[(3-prop-2-en-1-ylbiphenyl-4-yl)oxy]propan-1-amine | | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E. | | Deposit date: | 2010-01-13 | | Release date: | 2010-11-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
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3ACY
 | | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-702 | | Descriptor: | (1R)-4-[3-(2-benzylphenoxy)phenyl]-1-phosphonobutane-1-sulfonic acid, Dehydrosqualene synthase, MAGNESIUM ION | | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E. | | Deposit date: | 2010-01-13 | | Release date: | 2010-11-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
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1O55
 | | MOLECULAR STRUCTURE OF TWO CRYSTAL FORMS OF CYCLIC TRIADENYLIC ACID AT 1 ANGSTROM RESOLUTION | | Descriptor: | COBALT (II) ION, DNA (5'-CD(*AP*AP*AP)-3') | | Authors: | Gao, Y.G, Robinson, H, Guan, Y, Liaw, Y.C, van Boom, J.H, van der Marel, G.A, Wang, A.H. | | Deposit date: | 2003-08-20 | | Release date: | 2003-08-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.04 Å) | | Cite: | Molecular structure of two crystal forms of cyclic triadenylic acid at 1A resolution.
J.Biomol.Struct.Dyn., 16, 1998
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1O56
 | | MOLECULAR STRUCTURE OF TWO CRYSTAL FORMS OF CYCLIC TRIADENYLIC ACID AT 1 ANGSTROM RESOLUTION | | Descriptor: | DNA (5'-CD(*AP*AP*AP*)-3') | | Authors: | Gao, Y.G, Robinson, H, Guan, Y, Liaw, Y.C, van Boom, J.H, van der Marel, G.A, Wang, A.H. | | Deposit date: | 2003-08-20 | | Release date: | 2003-08-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (0.9 Å) | | Cite: | Molecular structure of two crystal forms of cyclic triadenylic acid at 1A resolution.
J.Biomol.Struct.Dyn., 16, 1998
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5AYR
 | | The crystal structure of SAUGI/human UDG complex | | Descriptor: | MAGNESIUM ION, Uncharacterized protein, Uracil-DNA glycosylase | | Authors: | Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J. | | Deposit date: | 2015-09-02 | | Release date: | 2016-06-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
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