5TXO
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![BU of 5txo by Molmil](/molmil-images/mine/5txo) | STRUCTURE OF Q151M complex (A62V, V75I, F77L, F116Y, Q151M) mutant HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3'), ... | Authors: | Das, K, Martinez, S.M, Arnold, E. | Deposit date: | 2016-11-17 | Release date: | 2017-04-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.546 Å) | Cite: | Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance. Antimicrob. Agents Chemother., 61, 2017
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5TXP
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![BU of 5txp by Molmil](/molmil-images/mine/5txp) | STRUCTURE OF Q151M complex (A62V, V75I, F77L, F116Y, Q151M) mutant HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DDATP | Descriptor: | 1,2-ETHANEDIOL, 2',3'-dideoxyadenosine triphosphate, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3'), ... | Authors: | Das, K, Martinez, S.M, Arnold, E. | Deposit date: | 2016-11-17 | Release date: | 2017-04-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance. Antimicrob. Agents Chemother., 61, 2017
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5TXN
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![BU of 5txn by Molmil](/molmil-images/mine/5txn) | STRUCTURE OF Q151M MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3'), ... | Authors: | Das, K, Martinez, S.M, Arnold, E. | Deposit date: | 2016-11-17 | Release date: | 2017-04-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance. Antimicrob. Agents Chemother., 61, 2017
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5TXM
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![BU of 5txm by Molmil](/molmil-images/mine/5txm) | STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DDATP | Descriptor: | 1,2-ETHANEDIOL, 2',3'-dideoxyadenosine triphosphate, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3'), ... | Authors: | Das, K, Martinez, S.M, Arnold, E. | Deposit date: | 2016-11-17 | Release date: | 2017-04-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance. Antimicrob. Agents Chemother., 61, 2017
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1VB0
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![BU of 1vb0 by Molmil](/molmil-images/mine/1vb0) | Atomic resolution structure of atratoxin-b, one short-chain neurotoxin from Naja atra | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cobrotoxin b, SULFATE ION | Authors: | Lou, X, Liu, Q, Teng, M, Niu, L, Huang, Q, Hao, Q. | Deposit date: | 2004-02-20 | Release date: | 2004-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (0.92 Å) | Cite: | The atomic resolution crystal structure of atratoxin determined by single wavelength anomalous diffraction phasing J.Biol.Chem., 279, 2004
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3JYT
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![BU of 3jyt by Molmil](/molmil-images/mine/3jyt) | K65R mutant HIV-1 reverse transcriptase cross-linked to DS-DNA and complexed with DATP as the incoming nucleotide substrate | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(DDG))-3'), DNA (5'-D(*A*TP*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ... | Authors: | Das, K, Arnold, E. | Deposit date: | 2009-09-22 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for the role of the K65r mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. J.Biol.Chem., 284, 2009
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3JSM
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![BU of 3jsm by Molmil](/molmil-images/mine/3jsm) | K65R mutant HIV-1 reverse transcriptase cross-linked to DS-DNA and complexed with tenofovir-diphosphate as the incoming nucleotide substrate | Descriptor: | DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(DDG))-3'), DNA (5'-D(*A*TP*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, ... | Authors: | Das, K, Arnold, E. | Deposit date: | 2009-09-10 | Release date: | 2009-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the role of the K65r mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. J.Biol.Chem., 284, 2009
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6E13
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![BU of 6e13 by Molmil](/molmil-images/mine/6e13) | Pseudomonas putida PqqB with a non-physiological zinc at the active site binds the substrate mimic, 5-cysteinyl-3,4-dihydroxyphenylalanine (5-Cys-DOPA), non-specifically but supports the proposed function of the enzyme in pyrroloquinoline quinone biosynthesis. | Descriptor: | 3-{[(2S)-2-amino-2-carboxyethyl]sulfanyl}-5-hydroxy-L-tyrosine, CHLORIDE ION, Coenzyme PQQ synthesis protein B, ... | Authors: | Evans III, R.L, Wilmot, C.M. | Deposit date: | 2018-07-09 | Release date: | 2019-05-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway. J.Am.Chem.Soc., 141, 2019
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5ZX1
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![BU of 5zx1 by Molmil](/molmil-images/mine/5zx1) | |
5ZMB
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![BU of 5zmb by Molmil](/molmil-images/mine/5zmb) | |
6LDP
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![BU of 6ldp by Molmil](/molmil-images/mine/6ldp) | Structure of CDK5R1-bound FEM1C | Descriptor: | Protein fem-1 homolog C,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-22 | Release date: | 2020-10-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LEN
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![BU of 6len by Molmil](/molmil-images/mine/6len) | Structure of NS11 bound FEM1C | Descriptor: | Protein fem-1 homolog C,NS11 peptide | Authors: | Chen, x, Liao, S, Xu, C. | Deposit date: | 2019-11-25 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.383 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LF0
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![BU of 6lf0 by Molmil](/molmil-images/mine/6lf0) | Structure of FEM1C | Descriptor: | Protein fem-1 homolog C, SULFATE ION | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-27 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LBN
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![BU of 6lbn by Molmil](/molmil-images/mine/6lbn) | Structure of SIL1-bound FEM1C | Descriptor: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-14 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.899 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LEY
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![BU of 6ley by Molmil](/molmil-images/mine/6ley) | Structure of Sil1G bound FEM1C | Descriptor: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-27 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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2NB4
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![BU of 2nb4 by Molmil](/molmil-images/mine/2nb4) | Solution structure of Q388A3 PDZ domain | Descriptor: | Putative uncharacterized protein | Authors: | Mei, S. | Deposit date: | 2016-01-24 | Release date: | 2016-02-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of Q388A3 PDZ domain from Trypanosoma brucei J.Struct.Biol., 194, 2016
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2N7S
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![BU of 2n7s by Molmil](/molmil-images/mine/2n7s) | Solution Structure of Leptospiral LigA4 Big Domain | Descriptor: | Ig-like repeat domain protein 1 | Authors: | Mei, S. | Deposit date: | 2015-09-17 | Release date: | 2015-10-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of leptospiral LigA4 Big domain. Biochem. Biophys. Res. Commun., 467, 2015
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2MQG
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![BU of 2mqg by Molmil](/molmil-images/mine/2mqg) | |
5ZUH
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![BU of 5zuh by Molmil](/molmil-images/mine/5zuh) | |
7D1L
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![BU of 7d1l by Molmil](/molmil-images/mine/7d1l) | complex structure of two RRM domains | Descriptor: | Embryonic developmental protein tofu-6, Uncharacterized protein | Authors: | Wang, X, Liao, S, Xu, C. | Deposit date: | 2020-09-14 | Release date: | 2021-08-25 | Last modified: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun, 12, 2021
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7D2Y
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![BU of 7d2y by Molmil](/molmil-images/mine/7d2y) | complex of two RRM domains | Descriptor: | Embryonic developmental protein tofu-6, RRM2, SULFATE ION | Authors: | Wang, X, Liao, S, Xu, C. | Deposit date: | 2020-09-17 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun, 12, 2021
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7EJS
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![BU of 7ejs by Molmil](/molmil-images/mine/7ejs) | Structure of ERH-2 bound to PICS-1 | Descriptor: | Enhancer of rudimentary homolog 2,Protein pid-3 | Authors: | Wang, X, Xu, C. | Deposit date: | 2021-04-02 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.387 Å) | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun, 12, 2021
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7EJO
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![BU of 7ejo by Molmil](/molmil-images/mine/7ejo) | Structure of ERH-2 bound to TOST-1 | Descriptor: | Enhancer of rudimentary homolog 2, Enhancer of rudimentary homolog 2,Protein tost-1 | Authors: | Wang, X, Xu, C. | Deposit date: | 2021-04-02 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.191 Å) | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun, 12, 2021
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4PUO
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![BU of 4puo by Molmil](/molmil-images/mine/4puo) | Crystal structure of HIV-1 reverse transcriptase in complex with RNA/DNA and Nevirapine | Descriptor: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*AP*UP*GP*GP*UP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*UP*GP*UP*G)-3', ... | Authors: | Das, K, Martinez, S.E, Arnold, E. | Deposit date: | 2014-03-13 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.901 Å) | Cite: | Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage. Nucleic Acids Res., 42, 2014
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4Q0B
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![BU of 4q0b by Molmil](/molmil-images/mine/4q0b) | Crystal structure of HIV-1 reverse transcriptase in complex with gap-RNA/DNA and Nevirapine | Descriptor: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*G)-3', 5'-R(*AP*UP*GP*GP*UP*CP*GP*GP*CP*GP*CP*CP*CP*G)-3', ... | Authors: | Das, K, Martinez, S.E, Arnold, E. | Deposit date: | 2014-04-01 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage. Nucleic Acids Res., 42, 2014
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