5ZMB
A-ubiquitin like protein from the trypanosoma brucei
Summary for 5ZMB
| Entry DOI | 10.2210/pdb5zmb/pdb |
| NMR Information | BMRB: 36175 |
| Descriptor | ubiquintin-like protein (1 entity in total) |
| Functional Keywords | structure from cyana 3.0, protein binding |
| Biological source | Trypanosoma brucei brucei TREU927 |
| Total number of polymer chains | 1 |
| Total formula weight | 9141.47 |
| Authors | |
| Primary citation | Mi, J.,Zhang, J.,Liao, S.,Tu, X. Solution structure of a ubiquitin-like protein from Trypanosoma brucei Protein Sci., 27:1831-1836, 2018 Cited by PubMed Abstract: Ubiquitin-like proteins, similar to ubiquitin, can either exist freely or be covalently attached to other proteins via an enzymatic cascade. The ubiquitin-like proteins play roles in multiple biological processes including transcription, stress responses, DNA repair and so on. In this study, a novel ubiquitin-like protein (TbUbl11) was identified in Trypanosoma brucei. The solution structure of TbUbl11 was solved by NMR spectroscopy. TbUbl11 adopts a conserved β-grasp fold composed by a five-stranded β-sheet curling around a central α-helix, similar to other ubiquitin-like proteins. Meanwhile, some differences between TbUbl11 and other ubiquitin-like proteins were also identified. Additionally, we revealed that TbUbl11 is located in the whole cell body of procyclic-form T. brucei. PubMed: 30058168DOI: 10.1002/pro.3492 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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