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BU of 5jdo by Molmil

T. congolense haptoglobin-haemoglobin receptor in complex with haemoglobin
Descriptor:	Haptoglobin-haemoglobin receptor, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:	Lane-Serff, H, Higgins, M.K.
Deposit date:	2016-04-17
Release date:	2016-04-27
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor. Elife, 5, 2016

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BU of 6sny by Molmil

Synthetic mimic of an EPCR-binding PfEMP1 bound to EPCR
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, ...
Authors:	Barber, N.M, Higgins, M.K.
Deposit date:	2019-08-27
Release date:	2019-09-04
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.11 Å)
Cite:	Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein. Msphere, 6, 2021

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BU of 2wau by Molmil

Structure of DBL6 epsilon domain from VAR2CSA
Descriptor:	ERYTHROCYTE MEMBRANE PROTEIN 1 (PFEMP1)
Authors:	Khunrae, P, Higgins, M.K.
Deposit date:	2009-02-16
Release date:	2009-08-18
Last modified:	2014-12-03
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Structural Comparison of Two Cspg-Binding Dbl Domains from the Var2Csa Protein Important in Malaria During Pregnancy. J.Mol.Biol., 393, 2009

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BU of 6rco by Molmil

PfRH5-binding monoclonal antibody R5.004
Descriptor:	ACETATE ION, GLYCEROL, R5.004 heavy chain, ...
Authors:	Alanine, D.G.W, Draper, S.J, Higgins, M.K.
Deposit date:	2019-04-11
Release date:	2019-06-26
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.66 Å)
Cite:	Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019

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BU of 6rcq by Molmil

PfRH5-binding monoclonal antibody R5.011
Descriptor:	ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ...
Authors:	Alanine, D.W.G, Draper, S.J, Higgins, M.K.
Deposit date:	2019-04-11
Release date:	2019-06-26
Last modified:	2019-07-10
Method:	X-RAY DIFFRACTION (2.28 Å)
Cite:	Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019

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BU of 6rcs by Molmil

PfRH5-binding monoclonal antibody R5.016
Descriptor:	ACETATE ION, R5.016 heavy chain, R5.016 light chain, ...
Authors:	Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K.
Deposit date:	2019-04-11
Release date:	2019-06-26
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019

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BU of 6s8t by Molmil

Structure of the ICAM-1-binding PfEMP1 IT4var13 DBLbeta domain
Descriptor:	Erythrocyte membrane protein 1
Authors:	Lennartz, F, Higgins, M.K.
Deposit date:	2019-07-10
Release date:	2019-09-25
Last modified:	2019-10-09
Method:	X-RAY DIFFRACTION (2.17 Å)
Cite:	Structural insights into diverse modes of ICAM-1 binding byPlasmodium falciparum-infected erythrocytes. Proc.Natl.Acad.Sci.USA, 116, 2019

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BU of 6s8u by Molmil

Structure of the PfEMP1 IT4var13 DBLbeta domain bound to ICAM-1
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 1, ...
Authors:	Lennartz, F, Higgins, M.K.
Deposit date:	2019-07-10
Release date:	2019-09-25
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (3.67 Å)
Cite:	Structural insights into diverse modes of ICAM-1 binding byPlasmodium falciparum-infected erythrocytes. Proc.Natl.Acad.Sci.USA, 116, 2019

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BU of 6soy by Molmil

Trypanosoma brucei transferrin receptor in complex with human transferrin
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, subunit of heterodimeric transferrin receptor, ...
Authors:	Trevor, C, Carrington, M, Higgins, M.K.
Deposit date:	2019-08-30
Release date:	2019-11-06
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion. Nat Microbiol, 4, 2019

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BU of 6soz by Molmil

Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, ...
Authors:	Trevor, C, Carrington, M, Higgins, M.K.
Deposit date:	2019-08-30
Release date:	2019-11-06
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.42 Å)
Cite:	Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion. Nat Microbiol, 4, 2019

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BU of 6r2s by Molmil

The structure of Plasmodium vivax Duffy binding protein (PvDBP) bound to human antibody DB9
Descriptor:	Antibody DB9 heavy chain, Antibody DB9 light chain, Duffy receptor
Authors:	Barber, N.M, Higgins, M.K.
Deposit date:	2019-03-18
Release date:	2019-03-27
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.04 Å)
Cite:	Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody. Nat Microbiol, 4, 2019

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BU of 6rcu by Molmil

PfRH5 bound to monoclonal antibodies R5.004 and R5.016
Descriptor:	R5.004 heavy chain, R5.004 light chain, R5.016 heavy chain, ...
Authors:	Alanine, D.W.G, Draper, S.J, Higgins, M.K.
Deposit date:	2019-04-11
Release date:	2019-06-26
Last modified:	2019-08-21
Method:	X-RAY DIFFRACTION (4.005 Å)
Cite:	Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019

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BU of 6rcv by Molmil

PfRH5 bound to monoclonal antibodies R5.011 and R5.016
Descriptor:	R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ...
Authors:	Alanine, D.W.G, Draper, S.J, Higgins, M.K.
Deposit date:	2019-04-11
Release date:	2019-06-26
Last modified:	2019-07-10
Method:	X-RAY DIFFRACTION (3.582 Å)
Cite:	Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019

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BU of 4bm7 by Molmil

Crystal Structure of IgG Fc F241A mutant with native glycosylation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, IG GAMMA-1 CHAIN C REGION
Authors:	Yu, X, Baruah, K, Harvey, D.J, Vasiljevic, S, Alonzi, D.S, Song, B, Higgins, M.K, Bowden, T.A, Crispin, M, Scanlan, C.N.
Deposit date:	2013-05-07
Release date:	2013-07-03
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Engineering Hydrophobic Protein-Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies. J.Am.Chem.Soc., 135, 2013

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BU of 6z2l by Molmil

Structure of Plasmodium falciparum P113 bound to antibody P3.2
Descriptor:	FAb fragment - VH chain, FAb fragment - VL chain, SULFATE ION, ...
Authors:	Campeotto, I, Higgins, K.M.
Deposit date:	2020-05-16
Release date:	2020-07-22
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site. Mbio, 11, 2020

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BU of 1hfa by Molmil

CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, PI(4,5)P2 complex
Descriptor:	CLATHRIN ASSEMBLY PROTEIN SHORT FORM, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:	Ford, M.G.J, Evans, P.R, McMahon, H.T.
Deposit date:	2000-11-30
Release date:	2001-02-12
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes Science, 291, 2001

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BU of 1hf8 by Molmil

CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein
Descriptor:	CLATHRIN ASSEMBLY PROTEIN SHORT FORM
Authors:	Ford, M.G.J, Evans, P.R, McMahon, H.T.
Deposit date:	2000-11-30
Release date:	2001-02-12
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes Science, 291, 2001

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BU of 1hg5 by Molmil

CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, inositol(1,2,3,4,5,6)P6 complex
Descriptor:	CLATHRIN ASSEMBLY PROTEIN SHORT FORM, INOSITOL HEXAKISPHOSPHATE
Authors:	Ford, M.G.J, Evans, P.R, McMahon, H.T.
Deposit date:	2000-12-12
Release date:	2001-02-12
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes Science, 291, 2001

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BU of 1hg2 by Molmil

CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, Inositol(4,5)P2 complex
Descriptor:	CLATHRIN ASSEMBLY PROTEIN SHORT FORM, D-MYO-INOSITOL-4,5-BISPHOSPHATE
Authors:	Ford, M.G.J, Evans, P.R, McMahon, H.T.
Deposit date:	2000-12-12
Release date:	2001-02-12
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes Science, 291, 2001

226707

數據於2024-10-30公開中

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