5C5Q
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![BU of 5c5q by Molmil](/molmil-images/mine/5c5q) | CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR | Descriptor: | (3R)-10-methyl-3-(propan-2-yl)-1,3,4,5-tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one, SULFATE ION, Tankyrase-2, ... | Authors: | Lukacs, C.M, Janson, C.A. | Deposit date: | 2015-06-21 | Release date: | 2015-08-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors. Acs Med.Chem.Lett., 6, 2015
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5HZG
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![BU of 5hzg by Molmil](/molmil-images/mine/5hzg) | The crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex | Descriptor: | (2Z)-2-methylbut-2-ene-1,4-diol, F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A, ... | Authors: | Yao, R.F, Ming, Z.H, Yan, L.M, Rao, Z.H, Lou, Z.Y, Xie, D.X. | Deposit date: | 2016-02-02 | Release date: | 2016-08-03 | Last modified: | 2016-08-31 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | DWARF14 is a non-canonical hormone receptor for strigolactone Nature, 536, 2016
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5HYW
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![BU of 5hyw by Molmil](/molmil-images/mine/5hyw) | The crystal structure of the D3-ASK1 complex | Descriptor: | F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A | Authors: | Yao, R.F, Ming, Z.H, Yan, L.M, Rao, Z.H, Lou, Z.Y, Xie, D.X. | Deposit date: | 2016-02-02 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | DWARF14 is a non-canonical hormone receptor for strigolactone Nature, 536, 2016
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8SIT
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![BU of 8sit by Molmil](/molmil-images/mine/8sit) | |
8SIS
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![BU of 8sis by Molmil](/molmil-images/mine/8sis) | |
8SIR
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![BU of 8sir by Molmil](/molmil-images/mine/8sir) | |
8SIQ
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![BU of 8siq by Molmil](/molmil-images/mine/8siq) | |
8SWH
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![BU of 8swh by Molmil](/molmil-images/mine/8swh) | |
6LQD
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![BU of 6lqd by Molmil](/molmil-images/mine/6lqd) | Structure of Enterovirus 71 in complex with NLD-22 | Descriptor: | 1-(2-azanylpyridin-4-yl)-3-[5-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenoxy]pentyl]imidazolidin-2-one, Capsid protein VP1, Capsid protein VP2, ... | Authors: | Zhang, M, Sun, Y, Wang, X, Guo, Y, Rao, Z. | Deposit date: | 2020-01-13 | Release date: | 2020-03-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.264 Å) | Cite: | Design, Synthesis, and Evaluation of Novel Enterovirus 71 Inhibitors as Therapeutic Drug Leads for the Treatment of Human Hand, Foot, and Mouth Disease. J.Med.Chem., 63, 2020
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8IMW
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![BU of 8imw by Molmil](/molmil-images/mine/8imw) | |
7DQZ
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![BU of 7dqz by Molmil](/molmil-images/mine/7dqz) | Crystal structure of SARS 3C-like protease in apo form | Descriptor: | 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2020-12-24 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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7EO7
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![BU of 7eo7 by Molmil](/molmil-images/mine/7eo7) | Crystal structure of HCoV-NL63 3C-like protease in complex with an inhibitor Shikonin | Descriptor: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | Deposit date: | 2021-04-21 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.24916625 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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7EO8
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![BU of 7eo8 by Molmil](/molmil-images/mine/7eo8) | Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin | Descriptor: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2021-04-21 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2808516 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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6KVN
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![BU of 6kvn by Molmil](/molmil-images/mine/6kvn) | |
8H3X
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![BU of 8h3x by Molmil](/molmil-images/mine/8h3x) | Bacteroide Fragilis Toxin in complex with nanobody 282 | Descriptor: | Fragilysin, ZINC ION, nanobody 282 | Authors: | Wen, Y, Guo, Y. | Deposit date: | 2022-10-09 | Release date: | 2023-02-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Screening and epitope characterization of diagnostic nanobody against total and activated Bacteroides fragilis toxin. Front Immunol, 14, 2023
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8H3Y
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![BU of 8h3y by Molmil](/molmil-images/mine/8h3y) | Bacteroide Fragilis Toxin in complex with nanobody 327 | Descriptor: | Fragilysin, Nanobody 327, ZINC ION | Authors: | Wen, Y, Guo, Y. | Deposit date: | 2022-10-09 | Release date: | 2023-02-08 | Last modified: | 2023-03-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Screening and epitope characterization of diagnostic nanobody against total and activated Bacteroides fragilis toxin. Front Immunol, 14, 2023
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6LCT
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![BU of 6lct by Molmil](/molmil-images/mine/6lct) | Crystal structure of catalytic inactive chloroplast resolvase NtMOC1 in complex with Holliday junction | Descriptor: | DNA (5'-D(*AP*AP*GP*AP*TP*GP*TP*CP*CP*CP*TP*CP*TP*GP*TP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*AP*CP*AP*GP*AP*GP*GP*AP*TP*GP*GP*AP*GP*CP*T)-3'), DNA (5'-D(*GP*CP*CP*TP*TP*GP*CP*TP*GP*GP*GP*AP*CP*AP*TP*CP*TP*T)-3'), ... | Authors: | Yan, J.J, Hong, S.X, Guan, Z.Y, Yin, P. | Deposit date: | 2019-11-19 | Release date: | 2020-04-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1. Nat Commun, 11, 2020
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6KVO
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![BU of 6kvo by Molmil](/molmil-images/mine/6kvo) | Crystal structure of chloroplast resolvase in complex with Holliday junction | Descriptor: | DNA (5'-D(*AP*CP*AP*AP*CP*AP*GP*AP*TP*GP*AP*TP*GP*GP*AP*GP*CP*T)-3'), DNA (5'-D(*GP*CP*CP*TP*TP*GP*CP*TP*TP*GP*GP*AP*CP*AP*TP*CP*TP*T)-3'), DNA (5'-D(P*AP*AP*GP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*TP*TP*GP*T)-3'), ... | Authors: | Yan, J.J, Hong, S.X, Guan, Z.Y, Yin, P. | Deposit date: | 2019-09-05 | Release date: | 2020-04-08 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1. Nat Commun, 11, 2020
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6LCM
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![BU of 6lcm by Molmil](/molmil-images/mine/6lcm) | Crystal structure of chloroplast resolvase ZmMOC1 with the magic triangle I3C | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, ZmMoc1 | Authors: | Yan, J.J, Hong, S.X, Guan, Z.Y, Yin, P. | Deposit date: | 2019-11-19 | Release date: | 2020-04-08 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1. Nat Commun, 11, 2020
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6J15
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![BU of 6j15 by Molmil](/molmil-images/mine/6j15) | Complex structure of GY-5 Fab and PD-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GY-5 heavy chain Fab, ... | Authors: | Chen, D, Tan, S, Zhang, H, Wang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | Deposit date: | 2018-12-27 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy. Iscience, 14, 2019
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4XEM
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![BU of 4xem by Molmil](/molmil-images/mine/4xem) | |
4XEO
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![BU of 4xeo by Molmil](/molmil-images/mine/4xeo) | |
7C2Q
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![BU of 7c2q by Molmil](/molmil-images/mine/7c2q) | The crystal structure of COVID-19 main protease in the apo state | Descriptor: | 3C-like proteinase | Authors: | Zhou, X.L, Zhong, F.L, Lin, C, Hu, X.H, Zhou, H, Wang, Q.S, Li, j, Zhang, J. | Deposit date: | 2020-05-08 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structure of SARS-CoV-2 main protease in the apo state. Sci China Life Sci, 64, 2021
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