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1ASW
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BU of 1asw by Molmil
AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 20% PEG 4000, 10% ISOPROPANOL, HEPES PH 7.5 USING SELENOMETHIONINE SUBSTITUTED PROTEIN; DATA COLLECTED AT-165 DEGREES C
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE, ISOPROPYL ALCOHOL
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-08-25
Release date:1995-11-14
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-resolution structure of the catalytic domain of avian sarcoma virus integrase.
J.Mol.Biol., 253, 1995
1KVA
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BU of 1kva by Molmil
E. COLI RIBONUCLEASE HI D134A MUTANT
Descriptor: RIBONUCLEASE H
Authors:Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
Deposit date:1996-10-04
Release date:1997-03-12
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1KVC
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BU of 1kvc by Molmil
E. COLI RIBONUCLEASE HI D134N MUTANT
Descriptor: RIBONUCLEASE H
Authors:Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
Deposit date:1996-10-04
Release date:1997-03-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
7VRL
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BU of 7vrl by Molmil
Solution structure of Rbfox RRM bound to a non-cognate RNA
Descriptor: RNA (5'-R(*UP*GP*CP*AP*UP*AP*U)-3'), RNA binding protein fox-1 homolog 1
Authors:Yang, F, Varani, G.
Deposit date:2021-10-23
Release date:2022-10-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity.
Nat Commun, 14, 2023
1KVB
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BU of 1kvb by Molmil
E. COLI RIBONUCLEASE HI D134H MUTANT
Descriptor: RIBONUCLEASE H
Authors:Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
Deposit date:1996-10-04
Release date:1997-03-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1QFW
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BU of 1qfw by Molmil
TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ...
Authors:Tegoni, M, Spinelli, S, Cambillau, C.
Deposit date:1999-04-15
Release date:2000-04-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.
J.Mol.Biol., 289, 1999
7FHN
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BU of 7fhn by Molmil
Structure of AtTPC1 D240A/D454A/E528A mutant with 1 mM Ca2+
Descriptor: CALCIUM ION, Two pore calcium channel protein 1,GFP
Authors:Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J.
Deposit date:2021-07-29
Release date:2021-12-01
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7FHO
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BU of 7fho by Molmil
Structure of AtTPC1 D240A/D454A/E528A mutant with 50 mM Ca2+
Descriptor: CALCIUM ION, Two pore calcium channel protein 1,GFP
Authors:Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J.
Deposit date:2021-07-29
Release date:2021-12-01
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7FHL
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BU of 7fhl by Molmil
Structure of AtTPC1 with 50 mM Ca2+
Descriptor: AtTPC1-Cter, CALCIUM ION, Two pore calcium channel protein 1,GFP
Authors:Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J.
Deposit date:2021-07-29
Release date:2021-12-01
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7ES2
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BU of 7es2 by Molmil
a mutant of glycosyktransferase in complex with UDP and Reb D
Descriptor: Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, rebaudioside D
Authors:Zhu, X.
Deposit date:2021-05-08
Release date:2021-12-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
7ERX
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BU of 7erx by Molmil
Glycosyltransferase in complex with UDP and STB
Descriptor: GLYCEROL, Glycosyltransferase, Steviolbioside, ...
Authors:Zhu, X.
Deposit date:2021-05-08
Release date:2021-12-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
7FHK
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BU of 7fhk by Molmil
Structure of AtTPC1 with 1 mM Ca2+
Descriptor: AtTPC1-Cter, CALCIUM ION, Two pore calcium channel protein 1,GFP
Authors:Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J.
Deposit date:2021-07-29
Release date:2021-12-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7ES1
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BU of 7es1 by Molmil
glycosyltransferase in complex with UDP and ST
Descriptor: Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, steviol-19-o-glucoside
Authors:Zhu, X.
Deposit date:2021-05-08
Release date:2021-12-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
7ERY
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BU of 7ery by Molmil
apo form of the glycosyltransferase
Descriptor: Glycosyltransferase
Authors:Zhu, X.
Deposit date:2021-05-08
Release date:2021-12-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
7ES0
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BU of 7es0 by Molmil
a rice glycosyltransferase in complex with UDP and REX
Descriptor: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, ...
Authors:Zhu, X.
Deposit date:2021-05-08
Release date:2021-12-08
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.395 Å)
Cite:Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Nat Commun, 12, 2021
6J4R
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BU of 6j4r by Molmil
Structural basis for the target DNA recognition and binding by the MYB domain of phosphate starvation response regulator 1
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*TP*AP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*CP*AP*TP*AP*TP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*TP*AP*TP*AP*CP*TP*G)-3'), ...
Authors:Jiang, M.Q, Sun, L.F, Isupov, M.N.
Deposit date:2019-01-10
Release date:2019-04-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the Target DNA recognition and binding by the MYB domain of phosphate starvation response 1.
Febs J., 286, 2019
6J4K
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BU of 6j4k by Molmil
Structural basis for the target DNA recognition and binding by the MYB domain of phosphate starvation response 1
Descriptor: GLYCEROL, MALONIC ACID, Protein PHOSPHATE STARVATION RESPONSE 1
Authors:Jiang, M.Q, Sun, L.F.
Deposit date:2019-01-09
Release date:2019-04-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural basis for the Target DNA recognition and binding by the MYB domain of phosphate starvation response 1.
Febs J., 286, 2019
6J5B
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BU of 6j5b by Molmil
Structural basis for the target DNA recognition and binding by the MYB domain of phosphate starvation response regulator 1
Descriptor: DNA (5'-D(*GP*GP*TP*AP*CP*AP*GP*TP*AP*TP*AP*TP*AP*CP*CP*AP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*TP*GP*GP*TP*AP*TP*AP*TP*AP*CP*TP*GP*TP*AP*CP*C)-3'), Protein PHOSPHATE STARVATION RESPONSE 1
Authors:Jiang, M.Q, Sun, L.F, Isupov, M.N, Wu, Y.K.
Deposit date:2019-01-10
Release date:2019-04-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the Target DNA recognition and binding by the MYB domain of phosphate starvation response 1.
Febs J., 286, 2019
5WH5
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BU of 5wh5 by Molmil
Crystal structure of the PDE4D2 catalytic domain in complex with inhibitor (R)-Zl-n-91
Descriptor: 1-[4-(difluoromethoxy)-3-{[(3R)-oxolan-3-yl]oxy}phenyl]-3-methylbutan-1-one, MAGNESIUM ION, ZINC ION, ...
Authors:Wang, H.
Deposit date:2017-07-14
Release date:2018-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of a PDE4-Specific Pocket for the Design of Selective Inhibitors.
Biochemistry, 57, 2018
6KKT
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BU of 6kkt by Molmil
human KCC1 structure determined in KCl and lipid nanodisc
Descriptor: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Liu, S, Chang, S, Ye, S, Bai, X, Guo, J.
Deposit date:2019-07-27
Release date:2019-10-23
Last modified:2020-08-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Science, 366, 2019
6KKR
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BU of 6kkr by Molmil
human KCC1 structure determined in KCl and detergent GDN
Descriptor: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Liu, S, Chang, S, Ye, S, Bai, X, Guo, J.
Deposit date:2019-07-27
Release date:2019-10-23
Last modified:2020-08-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Science, 366, 2019
5WH6
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BU of 5wh6 by Molmil
Crystal structure of PDE4D2 in complex with inhibitor (S_Zl-n-91)
Descriptor: 1-[4-(difluoromethoxy)-3-{[(3S)-oxolan-3-yl]oxy}phenyl]-3-methylbutan-1-one, MAGNESIUM ION, ZINC ION, ...
Authors:Ke, H, Wang, H.
Deposit date:2017-07-14
Release date:2018-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification of a PDE4-Specific Pocket for the Design of Selective Inhibitors.
Biochemistry, 57, 2018
5WEV
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BU of 5wev by Molmil
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
Descriptor: N-[2-(2,6-dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamide, Tyrosine-protein kinase JAK2
Authors:Ultsch, M.H, Magnuson, S.
Deposit date:2017-07-10
Release date:2017-09-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.
Bioorg. Med. Chem. Lett., 27, 2017
6KKU
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BU of 6kku by Molmil
human KCC1 structure determined in NaCl and GDN
Descriptor: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Liu, S, Chang, S, Ye, S, Bai, X, Guo, J.
Deposit date:2019-07-27
Release date:2019-10-23
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Science, 366, 2019
6KUJ
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BU of 6kuj by Molmil
Structure of influenza D virus polymerase bound to cRNA promoter in class 1
Descriptor: 3'-cRNA promoter, 5'-cRNA promoter, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation
NAT NANOTECHNOL, 2019

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數據於2024-07-17公開中

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