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1M75
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BU of 1m75 by Molmil
Crystal Structure of the N208S Mutant of L-3-Hydroxyacyl-COA Dehydrogenase in Complex with NAD and Acetoacetyl-COA
Descriptor: 3-HYDROXYACYL-COA DEHYDROGENASE, ACETOACETYL-COENZYME A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Barycki, J.J, Banaszak, L.J.
Deposit date:2002-07-18
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the N208S Mutant of L-3-Hydroxyacyl-COA Dehydrogenase in Complex with NAD and Acetoacetyl-COA
To be Published
4HKB
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BU of 4hkb by Molmil
CH67 Fab (unbound) from the CH65-67 Lineage
Descriptor: CH67 heavy chain, CH67 light chain
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-15
Release date:2012-11-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HK3
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BU of 4hk3 by Molmil
I2 Fab (unbound) from CH65-CH67 Lineage
Descriptor: I2 heavy chain, I2 light chain
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-14
Release date:2012-11-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HKX
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BU of 4hkx by Molmil
Influenza hemagglutinin in complex with CH67 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CH67 heavy chain, CH67 light chain, ...
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-15
Release date:2012-11-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HK0
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BU of 4hk0 by Molmil
UCA Fab (unbound) from CH65-CH67 Lineage
Descriptor: UCA heavy chain, UCA light chain
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-14
Release date:2012-11-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JDH
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BU of 4jdh by Molmil
Crystal structure of Serine/threonine-protein kinase PAK 4 in complex with Paktide T peptide substrate
Descriptor: Paktide T, Serine/threonine-protein kinase PAK 4
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2013-02-25
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.
Mol.Cell, 53, 2014
4JDI
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BU of 4jdi by Molmil
Crystal structure of Serine/threonine-protein kinase PAK 4 in complex with Paktide S peptide substrate
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Paktide S, ...
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2013-02-25
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.
Mol.Cell, 53, 2014
4JDJ
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BU of 4jdj by Molmil
Crystal structure of Serine/threonine-protein kinase PAK 4 F461V mutant in complex with Paktide T peptide substrate
Descriptor: Paktide T, Serine/threonine-protein kinase PAK 4
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2013-02-25
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.
Mol.Cell, 53, 2014
4JDK
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BU of 4jdk by Molmil
Crystal structure of Serine/threonine-protein kinase PAK 4 F461V mutant in complex with Paktide S peptide substrate
Descriptor: Paktide S, Serine/threonine-protein kinase PAK 4
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2013-02-25
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.
Mol.Cell, 53, 2014
4KIN
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BU of 4kin by Molmil
Crystal structure of mitogen-activated protein kinase 14 (P38-H5) complex with 5-(2-CHLOROPHENYL)-N-(5-(CYCLOPROPYLCARBAMOYL)-2-METHYLPHENYL)-2-THIOPHENECARBOXAMIDE
Descriptor: 5-(2-chlorophenyl)-N-[5-(cyclopropylcarbamoyl)-2-methylphenyl]thiophene-2-carboxamide, Mitogen-activated protein kinase 14
Authors:Sack, J.S, Tokarski, J.S.
Deposit date:2013-05-02
Release date:2013-06-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The Identification of Novel P38-Alpha Isoform Selective Kinase Inhibitors Having an Unprecedented P38-Alpha Binding Mode
Bioorg.Med.Chem.Lett., 23, 2013
4KIQ
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BU of 4kiq by Molmil
Crystal structure of mitogen-activated protein kinase 14 (P38-H5) complex with ETHYL 6-((5-(CYCLOPROPYLCARBAMOYL)-2-METHYLPHENYL)CARBAMOYL)-1H-INDOLE-1-CARBOXYLATE
Descriptor: Mitogen-activated protein kinase 14, ethyl 6-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]carbamoyl}-1H-indole-1-carboxylate
Authors:Sack, J.S, Tokarski, J.S.
Deposit date:2013-05-02
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Identification of Novel P38-Alpha Isoform Selective Kinase Inhibitors Having an Unprecedented P38-Alpha Binding Mode
Bioorg.Med.Chem.Lett., 23, 2013
4KS8
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BU of 4ks8 by Molmil
PAK6 kinase domain in complex with sunitinib
Descriptor: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, Serine/threonine-protein kinase PAK 6
Authors:Gao, J, Boggon, T.J.
Deposit date:2013-05-17
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6.
Plos One, 8, 2013
4KS7
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BU of 4ks7 by Molmil
PAK6 kinase domain in complex with PF-3758309
Descriptor: ISOPROPYL ALCOHOL, PF-3758309, Serine/threonine-protein kinase PAK 6
Authors:Gao, J, Boggon, T.J.
Deposit date:2013-05-17
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6.
Plos One, 8, 2013
4KIP
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BU of 4kip by Molmil
Crystal structure of mitogen-activated protein kinase 14 (P38-H5) complex with 2-(2-CHLOROPHENYL)-N-(5-(CYCLOPROPYLCARBAMOYL)-2-METHYLPHENYL)-1,3-THIAZOLE-5-CARBOXAMIDE
Descriptor: 2-(2-chlorophenyl)-N-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-1,3-thiazole-5-carboxamide, Mitogen-activated protein kinase 14
Authors:Sack, J.S, Tokarski, J.S.
Deposit date:2013-05-02
Release date:2013-06-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:The Identification of Novel P38-Alpha Isoform Selective Kinase Inhibitors Having an Unprecedented P38-Alpha Binding Mode
Bioorg.Med.Chem.Lett., 23, 2013
3N7Z
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BU of 3n7z by Molmil
Crystal structure of acetyltransferase from Bacillus anthracis
Descriptor: Acetyltransferase, GNAT family, SODIUM ION
Authors:Chang, C, Wu, R, Gornicki, P, Zhang, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-27
Release date:2010-06-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis.
Biochemistry, 54, 2015
4NC4
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BU of 4nc4 by Molmil
Crystal structure of photoreceptor AtUVR8 mutant W285F and light-induced structural changes at 120K
Descriptor: MAGNESIUM ION, Ultraviolet-B receptor UVR8
Authors:Yang, X, Zeng, X, Zhao, K.-H, Ren, Z.
Deposit date:2013-10-23
Release date:2016-10-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.
Nat Plants, 1, 2015
3BAY
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BU of 3bay by Molmil
N298S Variant of Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, CALCIUM ION, ...
Authors:Fredriksen, J.R, Maurus, R, Brayer, G.D.
Deposit date:2007-11-08
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAX
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BU of 3bax by Molmil
N298S Variant of Human Pancreatic Alpha-Amylase in Complex with Azide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, CALCIUM ION, ...
Authors:Maurus, R, Brayer, G.D.
Deposit date:2007-11-08
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAK
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BU of 3bak by Molmil
N298S mutant of Human Pancreatic Alpha-Amylase in complex with nitrate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRATE ION, ...
Authors:Fredriksen, J.R, Maurus, R, Brayer, G.D.
Deposit date:2007-11-08
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
8H08
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BU of 8h08 by Molmil
SARS-CoV-2 BA.1 variants S ectodomain trimer in complex with neutralizing antibody 10-5B and 6-2C
Descriptor: 10-5B H chain, 10-5B L chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, X, Wang, Z.
Deposit date:2022-09-28
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants.
Nat Commun, 14, 2023
4NCC
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BU of 4ncc by Molmil
Neutralizing antibody to murine norovirus
Descriptor: Fab fragment heavy, Fab fragment light
Authors:Smith, T, Li, M.
Deposit date:2013-10-24
Release date:2014-02-19
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization.
J.Virol., 88, 2014
8H07
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BU of 8h07 by Molmil
SARS-CoV-2 BA.4 variants S ectodomain trimer in complex with neutralizing antibody 10-5B and 6-2C
Descriptor: 10-5B H chain, 10-5B L chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, X, Wang, Z.
Deposit date:2022-09-28
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants.
Nat Commun, 14, 2023
3BAI
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BU of 3bai by Molmil
Human Pancreatic Alpha Amylase with Bound Nitrate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRATE ION, ...
Authors:Fredriksen, J.R, Maurus, R, Brayer, G.D.
Deposit date:2007-11-07
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAW
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BU of 3baw by Molmil
Human pancreatic alpha-amylase complexed with azide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, CALCIUM ION, ...
Authors:Maurus, R, Brayer, G.D.
Deposit date:2007-11-08
Release date:2008-03-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
4NBM
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BU of 4nbm by Molmil
Crystal structure of UVB photoreceptor UVR8 and light-induced structural changes at 180K
Descriptor: MAGNESIUM ION, Ultraviolet-B receptor UVR8
Authors:Yang, X, Zeng, X, Zhao, K.-H, Ren, Z.
Deposit date:2013-10-23
Release date:2016-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.
Nat Plants, 1, 2015

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數據於2024-07-17公開中

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