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7XF0
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BU of 7xf0 by Molmil
Crystal strucutre of CasDinG in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CasDinG
Authors:Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N.
Deposit date:2022-03-31
Release date:2023-07-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XF1
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BU of 7xf1 by Molmil
Crystal strucutre of apoCasDinG in complex with ssDNA
Descriptor: CasDinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')
Authors:Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N.
Deposit date:2022-03-31
Release date:2023-07-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG1
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BU of 7xg1 by Molmil
CryoEM structure of type IV-A Csf-crRNA binary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
Mol.Cell, 83, 2023
7XFZ
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BU of 7xfz by Molmil
CryoEM structure of type IV-A Csf-crRNAsp14-dsDNA ternary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG0
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BU of 7xg0 by Molmil
CryoEM structure of type IV-A Csf-crRNA-dsDNA ternary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG3
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BU of 7xg3 by Molmil
CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG4
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BU of 7xg4 by Molmil
CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex in a second state
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG2
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BU of 7xg2 by Molmil
CryoEM structure of type IV-A NTS-nicked dsDNA bound Csf-crRNA ternary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
5ZVB
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BU of 5zvb by Molmil
APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dT9)
Descriptor: APEBEC3F/ssDNA-T9, CACODYLATE ION, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*T)-3'), ...
Authors:Cheng, C, Zhang, T.L, Wang, C.X, Lan, W.X, Ding, J.P, Cao, C.Y.
Deposit date:2018-05-09
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA
Chin.J.Chem., 36, 2018
7Y0I
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BU of 7y0i by Molmil
Solution structures of ASH1L PHD domain in complex with H3K4me2 peptide
Descriptor: ALA-ARG-THR-MLY-GLN-THR-ALA-ARG-LYS-SER-THR-GLY-GLY-LYS-ALA, Histone-lysine N-methyltransferase ASH1L, ZINC ION
Authors:Yu, M, Zeng, L.
Deposit date:2022-06-05
Release date:2022-10-12
Method:SOLUTION NMR
Cite:Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Front Oncol, 12, 2022
7YHQ
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BU of 7yhq by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with a covalent-linked reaction intermediate at 3.9 Angstroms resolution
Descriptor: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1
Authors:Du, X, Du, J.
Deposit date:2022-07-14
Release date:2022-11-30
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7YHO
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BU of 7yho by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with TG mismatch dsDNA at 3.3 Angstroms resolution
Descriptor: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1
Authors:Du, X, Du, J.
Deposit date:2022-07-14
Release date:2022-11-30
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7YHP
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BU of 7yhp by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with 5mC-dsDNA at 3.1 Angstroms resolution
Descriptor: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,REPRESSOR OF SILENCING 1,DNA glycosylase/AP lyase ROS1
Authors:Du, X, Du, J.
Deposit date:2022-07-14
Release date:2022-11-30
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7Y85
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BU of 7y85 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to self RNA target
Descriptor: CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-06-22
Release date:2022-12-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
7Y81
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BU of 7y81 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to non-self RNA target
Descriptor: MAGNESIUM ION, Non-self RNA target, RAMP superfamily protein, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-06-22
Release date:2022-12-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
7Y80
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BU of 7y80 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA binary complex
Descriptor: MAGNESIUM ION, RAMP superfamily protein, ZINC ION, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-06-22
Release date:2022-12-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
7Y82
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BU of 7y82 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to self RNA target
Descriptor: MAGNESIUM ION, RAMP superfamily protein, Self RNA target, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-06-22
Release date:2022-12-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
7Y83
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BU of 7y83 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to non-self RNA target
Descriptor: CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-06-22
Release date:2022-12-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
7Y84
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BU of 7y84 by Molmil
CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease
Descriptor: CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-06-22
Release date:2022-12-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
4X6M
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BU of 4x6m by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR 1-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl}-3-[2-(aminomethyl)-5-chlorobenzyl]urea
Descriptor: 1,2-ETHANEDIOL, 1-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl}-3-[2-(aminomethyl)-5-chlorobenzyl]urea, Coagulation factor XI, ...
Authors:Wei, A.
Deposit date:2014-12-08
Release date:2015-02-18
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.
Bioorg.Med.Chem.Lett., 25, 2015
4X6N
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BU of 4x6n by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR 1-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl}-3-[5-chloro-2-(1H-tetrazol-1-yl)benzyl]urea
Descriptor: 1,2-ETHANEDIOL, 1-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl}-3-[5-chloro-2-(1H-tetrazol-1-yl)benzyl]urea, Coagulation factor XI, ...
Authors:Wei, A.
Deposit date:2014-12-08
Release date:2015-02-18
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.
Bioorg.Med.Chem.Lett., 25, 2015
5ZVA
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BU of 5zva by Molmil
APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dC9)
Descriptor: APEBEC3F/ssDNA-C9, CACODYLATE ION, DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*CP*T)-3'), ...
Authors:Cheng, C, Zhang, T.L, Wang, C.X, Lan, W.X, Ding, J.P, Cao, C.Y.
Deposit date:2018-05-09
Release date:2018-11-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA
Chin.J.Chem., 36, 2018
4X6O
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BU of 4x6o by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl (4-{4-chloro-2-[(1S)-1-({3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]propanoyl}amino)-2-phenylethyl]-1H-imidazol-5-yl}phenyl)carbamate
Descriptor: 1,2-ETHANEDIOL, Coagulation factor XI, light chain, ...
Authors:Wei, A.
Deposit date:2014-12-08
Release date:2015-02-18
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.
Bioorg.Med.Chem.Lett., 25, 2015
4HKF
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BU of 4hkf by Molmil
Crystal structure of Danio rerio MEC-17 catalytic domain in complex with acetyl-CoA
Descriptor: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, SULFATE ION
Authors:Li, W, Zhong, C, Sun, B, Xu, S, Zhang, T, Ding, J.
Deposit date:2012-10-15
Release date:2012-12-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis of the acetyltransferase activity of MEC-17 towards alpha- tubulin
Cell Res., 22, 2012
4X6P
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BU of 4x6p by Molmil
FACTOR XIA (PICHIA PASTORIS; C500S [C122S]) IN COMPLEX WITH THE INHIBITOR (2E)-N-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-1H-imidazol-2-yl]-2-phenylethyl}-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enamide
Descriptor: (2E)-N-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-1H-imidazol-2-yl]-2-phenylethyl}-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
Authors:Sheriff, S.
Deposit date:2014-12-08
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.
Bioorg.Med.Chem.Lett., 25, 2015

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數據於2024-07-10公開中

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