5COS
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3B5Z
| Crystal Structure of MsbA from Salmonella typhimurium with ADP Vanadate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lipid A export ATP-binding/permease protein msbA, VANADATE ION | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3B5W
| Crystal Structure of Eschericia coli MsbA | Descriptor: | Lipid A export ATP-binding/permease protein msbA | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (5.3 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
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5CI2
| Ribonucleotide reductase Y122 2,3,6-F3Y variant | Descriptor: | MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 subunit beta, SULFATE ION | Authors: | Funk, M.A, Drennan, C.L. | Deposit date: | 2015-07-10 | Release date: | 2016-06-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an Example. J.Am.Chem.Soc., 138, 2016
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5CI1
| Ribonucleotide reductase Y122 2,3-F2Y variant | Descriptor: | CHLORIDE ION, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1, ... | Authors: | Funk, M.A, Drennan, C.L. | Deposit date: | 2015-07-10 | Release date: | 2016-06-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an Example. J.Am.Chem.Soc., 138, 2016
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5CJV
| Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate isovaleryl-coenzyme A | Descriptor: | 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Jost, M, Drennan, C.L. | Deposit date: | 2015-07-15 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases. J.Biol.Chem., 290, 2015
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5CNS
| Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to CDP and dATP at 2.97 Angstroms resolution | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, ... | Authors: | Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L. | Deposit date: | 2015-07-18 | Release date: | 2016-01-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.975 Å) | Cite: | Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife, 5, 2016
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5CI0
| Ribonucleotide reductase Y122 3,5-F2Y variant | Descriptor: | MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1, beta subunit, ... | Authors: | Funk, M.A, Drennan, C.L. | Deposit date: | 2015-07-10 | Release date: | 2016-06-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an Example. J.Am.Chem.Soc., 138, 2016
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5CNU
| Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to ADP and dGTP at 3.40 Angstroms resolution | Descriptor: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L. | Deposit date: | 2015-07-18 | Release date: | 2016-01-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife, 5, 2016
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2YCB
| Structure of the archaeal beta-CASP protein with N-terminal KH domains from Methanothermobacter thermautotrophicus | Descriptor: | CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR, PHOSPHATE ION, POTASSIUM ION, ... | Authors: | Silva, A.P.G, Chechik, M, Byrne, R.T, Waterman, D.G, Ng, C.L, Dodson, E.J, Koonin, E.V, Antson, A.A, Smits, C. | Deposit date: | 2011-03-13 | Release date: | 2011-05-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure and Activity of a Novel Archaeal Beta-Casp Protein with N-Terminal Kh Domains. Structure, 19, 2011
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5D7F
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3B5X
| Crystal Structure of MsbA from Vibrio cholerae | Descriptor: | Lipid A export ATP-binding/permease protein msbA | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
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5D08
| Crystal structure of selenomethionine-labeled epoxyqueuosine reductase | Descriptor: | CHLORIDE ION, COBALAMIN, Epoxyqueuosine reductase, ... | Authors: | Dowling, D.P, Miles, Z.D, Kohrer, C, Bandarian, V, Drennan, C.L. | Deposit date: | 2015-08-02 | Release date: | 2016-09-28 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (1.747 Å) | Cite: | Molecular basis of cobalamin-dependent RNA modification. Nucleic Acids Res., 44, 2016
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2Z8Y
| Xenon-bound structure of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase(CODH/ACS) from Moorella thermoacetica | Descriptor: | COPPER (I) ION, Carbon monoxide dehydrogenase/acetyl CoA synthase subunit alpha, Carbon monoxide dehydrogenase/acetyl CoA synthase subunit beta, ... | Authors: | Doukov, T.I, Blasiak, L.C, Drennan, C.L. | Deposit date: | 2007-09-12 | Release date: | 2008-03-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Xenon in and at the End of the Tunnel of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase Biochemistry, 47, 2008
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5D0B
| Crystal structure of epoxyqueuosine reductase with a tRNA-TYR epoxyqueuosine-modified tRNA stem loop | Descriptor: | COBALAMIN, Epoxyqueuosine reductase, GLYCEROL, ... | Authors: | Dowling, D.P, Miles, Z.D, Kohrer, C, Bandarian, V, Drennan, C.L. | Deposit date: | 2015-08-03 | Release date: | 2016-09-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.645 Å) | Cite: | Molecular basis of cobalamin-dependent RNA modification. Nucleic Acids Res., 44, 2016
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4ZWX
| Engineered Carbonic Anhydrase IX mimic in complex with glucosyl sulfamate inhibitor | Descriptor: | (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-{[5-(sulfamoyloxy)pentyl]sulfamoyl}-D-allitol, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | Authors: | Mahon, B.P, Lomelino, C.L, Salguero, A.L, McKenna, R. | Deposit date: | 2015-05-19 | Release date: | 2015-10-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.696 Å) | Cite: | Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates. J.Med.Chem., 58, 2015
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4ZXH
| Crystal Structure of holo-AB3403 a four domain nonribosomal peptide synthetase from Acinetobacter Baumanii | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4'-PHOSPHOPANTETHEINE, ABBFA_003403, ... | Authors: | Drake, E.J, Miller, B.R, Allen, C.L, Gulick, A.M. | Deposit date: | 2015-05-20 | Release date: | 2015-12-30 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of two distinct conformations of holo-non-ribosomal peptide synthetases. Nature, 529, 2016
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5D0K
| Structure of UbE2D2:RNF165:Ub complex | Descriptor: | Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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5D0I
| Structure of RING finger protein 165 | Descriptor: | RING finger protein 165, SULFATE ION, ZINC ION | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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5D0M
| Structure of UbE2D2:RNF165:Ub complex | Descriptor: | PHOSPHATE ION, Polyubiquitin-B, RING finger protein 165, ... | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2016-01-20 | Method: | X-RAY DIFFRACTION (1.913 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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3BKT
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3BS9
| X-ray structure of human TIA-1 RRM2 | Descriptor: | IODIDE ION, Nucleolysin TIA-1 isoform p40 | Authors: | Kumar, A.O, Kielkopf, C.L. | Deposit date: | 2007-12-22 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of the central RNA recognition motif of human TIA-1 at 1.95A resolution. Biochem.Biophys.Res.Commun., 367, 2008
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5DG5
| CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET IN COMPLEX WITH ALTIRATINIB ANALOG DP-4157 | Descriptor: | Hepatocyte growth factor receptor, N-(2,5-difluoro-4-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxam ide | Authors: | Smith, B.D, Kaufman, M.D, Leary, C.B, Turner, B.A, Wise, S.A, Ahn, Y.M, Booth, R.J, Caldwell, T.M, Ensinger, C.L, Hood, M.M, Lu, W.-P, Patt, T.W, Patt, W.C, Rutkoski, T.J, Samarakoon, T, Telikepalli, H, Vogeti, L, Vogeti, S, Yates, K.M, Chun, L, Stewart, L.J, Clare, M, Flynn, D.L. | Deposit date: | 2015-08-27 | Release date: | 2016-08-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2. Mol.Cancer Ther., 14, 2015
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5DFL
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5DA5
| Crystal structure of Rhodospirillum rubrum Rru_A0973 | Descriptor: | CALCIUM ION, FE (III) ION, GLYCOLIC ACID, ... | Authors: | He, D, Vanden Hehier, S, Georgiev, A, Altenbach, K, Tarrant, E, Mackay, C.L, Waldron, K.J, Clarke, D.J, Marles-Wright, J. | Deposit date: | 2015-08-19 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.064 Å) | Cite: | Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments. Elife, 5, 2016
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