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Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with D-peptide
Descriptor:	2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Kadam, R.U, Wilson, I.A.
Deposit date:	2024-10-12
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (2.37 Å)
Cite:	De Novo design of D-peptide ligands To Be Published

5CJQ

Crystal structure of a trimeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor:	CR9114 heavy chain, CR9114 light chain, Designed influenza hemagglutinin stem #4900, ...
Authors:	Zhu, X, Wilson, I.A.
Deposit date:	2015-07-14
Release date:	2015-09-09
Last modified:	2024-11-13
Method:	X-RAY DIFFRACTION (3.6 Å)
Cite:	A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen. Science, 349, 2015

9CPQ

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-44 and CC12.3
Descriptor:	CC12.3 Fab heavy chain, CC12.3 Fab light chain, CITRIC ACID, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (2.88 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPR

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-90 and CC12.3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPV

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0614 and CC12.3
Descriptor:	C03-0614 Fab heavy chain, C03-0614 Fab light chain, CC12.3 Fab heavy chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPT

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-92 and CC12.3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (3.51 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPW

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C11-1036 and CC12.3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C11-1036 Fab heavy chain, C11-1036 Fab light chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPS

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-91 and CC12.3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (3.03 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPP

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-17 and CC12.3
Descriptor:	CC12.3 Fab heavy chain, CC12.3 Fab light chain, CITRIC ACID, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (3.19 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPX

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0138 and CC12.3
Descriptor:	C03-0138 Fab heavy chain, C03-0138 Fab light chain, CC12.3 Fab heavy chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPU

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0304 and CC12.3
Descriptor:	C03-0304 Fab heavy chain, C03-0304 Fab light chain, CC12.3 Fab heavy chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9CPY

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C11-0860 and CC12.3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, C11-0860 Fab heavy chain, C11-0860 Fab light chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

5BZW

Crystal Structure of PCDN-27B, an antibody from the PCDN family of HIV-1 antibodies
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2B3 HIV Antibody heavy chain, 2B3 HIV Antibody light chain, ...
Authors:	Garces, F, WILSON, I.A.
Deposit date:	2015-06-11
Release date:	2016-05-25
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch. Immunity, 44, 2016

5CEX

Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
Descriptor:	Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ...
Authors:	Garces, F, Wilson, I.A.
Deposit date:	2015-07-07
Release date:	2015-12-23
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.105 Å)
Cite:	Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity, 43, 2015

5AWN

Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab
Descriptor:	Heavy chain of 3BC176 Fab, Light chain of 3BC176 Fab
Authors:	Lee, J.H, Wilson, I.A, Ward, A.B.
Deposit date:	2015-07-06
Release date:	2015-11-11
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.887 Å)
Cite:	Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun, 6, 2015

5CJS

Crystal structure of a monomeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 heavy chain, CR9114 light chain, ...
Authors:	Zhu, X, Wilson, I.A.
Deposit date:	2015-07-15
Release date:	2015-09-09
Last modified:	2024-11-06
Method:	X-RAY DIFFRACTION (4.3 Å)
Cite:	A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen. Science, 349, 2015

8U03

Crystal structure of non-glycosylated 10E8-GT10.1 scaffold in complex with a human 10E8 NGS precursor (10E8-NGS-03)
Descriptor:	10E8-GT10.1 epitope scaffold, 10E8-NGS-03 Fab Light Chain, 10E8-NGS-03 Fab heavy chain, ...
Authors:	Irimia, A, Wilson, I.A.
Deposit date:	2023-08-28
Release date:	2024-06-12
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.72 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

8U44

CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06
Descriptor:	05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Moore, N, Han, J, Ward, A.B, Wilson, I.A.
Deposit date:	2023-09-08
Release date:	2024-06-26
Last modified:	2025-05-28
Method:	ELECTRON MICROSCOPY (3.41 Å)
Cite:	Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024

8TY7

Crystal structure of 05.GC.w2.3C10 Fab in complex with H1 HA from A/California/04/2009(H1N1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w2_3C10, heavy chain, ...
Authors:	Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:	2023-08-24
Release date:	2024-06-26
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (3.21 Å)
Cite:	Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024

8TZN

Crystal structure of 10E8-GT10.2 HIV-1 MPER scaffold in complex with a non-human primate W3-01 Fab
Descriptor:	10E8-GT10.2 MPER scaffold, W3-01 Fab Heavy Chain, W3-01 Fab Light Chain
Authors:	Lee, C.C.D, Wilson, I.A.
Deposit date:	2023-08-27
Release date:	2024-06-12
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.11 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

8TXP

Crystal structure of 05.GC.w13.01 Fab in complex with H1 HA from A/California/04/2009(H1N1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_A, Fab heavy chain, ...
Authors:	Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:	2023-08-24
Release date:	2024-06-26
Last modified:	2024-11-06
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024

8TZW

Crystal structure of 10E8-GT4 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor:	10E8-GT4 epitope scaffold, 10E8-IGL1 Fab Light Chain, 10E8-IGL1 Fab heavy chain
Authors:	Irimia, A, Wilson, I.A.
Deposit date:	2023-08-28
Release date:	2024-06-12
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (2.66 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

8TXM

Crystal structure of 05.GC.w13.02 Fab in complex with H1 HA from A/California/04/2009(H1N1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_B, ...
Authors:	Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:	2023-08-23
Release date:	2024-06-26
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.25 Å)
Cite:	Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024

8U08

Crystal structure of 10E8-GT11 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor:	10E8-GT11 epitope scaffold, 10E8-IGL1 heavy chain, 10E8-IGL1 light chain, ...
Authors:	Irimia, A, Wilson, I.A.
Deposit date:	2023-08-28
Release date:	2024-06-12
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (1.98 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

8V06

Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 9 days
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ...
Authors:	Yuan, M, Wilson, I.A.
Deposit date:	2023-11-17
Release date:	2024-03-13
Last modified:	2024-06-19
Method:	X-RAY DIFFRACTION (2.73 Å)
Cite:	Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024

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