7M65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m65 by Molmil](/molmil-images/mine/7m65) | Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 4 | Descriptor: | Islet amyloid polypeptide | Authors: | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2021-03-25 | Release date: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores Nat.Struct.Mol.Biol., 28, 2021
|
|
2APQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2apq by Molmil](/molmil-images/mine/2apq) | Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop. | Descriptor: | PHOSPHATE ION, Ribonuclease | Authors: | Sambashivan, S, Liu, Y, Sawaya, M.R, Gingery, M, Eisenberg, D. | Deposit date: | 2005-08-16 | Release date: | 2005-09-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature, 437, 2005
|
|
7N8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n8r by Molmil](/molmil-images/mine/7n8r) | FGTGFG segment from the Nucleoporin p54, residues 63-68 | Descriptor: | FGTGFG segment from the Nucleoporin p54, residues 63-68, trifluoroacetic acid | Authors: | Hughes, M.P, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2021-06-15 | Release date: | 2022-02-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Extended beta-Strands Contribute to Reversible Amyloid Formation. Acs Nano, 16, 2022
|
|
7N2G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2g by Molmil](/molmil-images/mine/7n2g) | MicroED structure of human CPEB3 segment(154-161) kinked polymorph phased by ARCIMBOLDO-BORGES | Descriptor: | CPEB3 | Authors: | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-29 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.201 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
7N2K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2k by Molmil](/molmil-images/mine/7n2k) | MicroED structure of sequence variant of repeat segment of the yeast prion New1p phased by ARCIMBOLDO-BORGES | Descriptor: | prion New1p | Authors: | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-29 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.301 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
7N2L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2l by Molmil](/molmil-images/mine/7n2l) | MicroED structure of a mutant mammalian prion segment | Descriptor: | prion protein | Authors: | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-29 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (0.9 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
7N2J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2j by Molmil](/molmil-images/mine/7n2j) | MicroED structure of a mutant mammalian prion segment phased by ARCIMBOLDO-BORGES | Descriptor: | prion protein | Authors: | Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-29 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
7N2F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2f by Molmil](/molmil-images/mine/7n2f) | MicroED structure of human CPEB3 segment (154-161) straight polymorph phased by ARCIMBOLDO-BORGES | Descriptor: | CPEB3 | Authors: | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-29 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.2 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
7N2H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2h by Molmil](/molmil-images/mine/7n2h) | X-Ray structure of a sequence variant of a repeat segment of the yeast prion New1p | Descriptor: | prion New1p | Authors: | Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-29 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.102 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
7N2I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2i by Molmil](/molmil-images/mine/7n2i) | MicroED structure of human LECT2 (45-53) phased by ARCIMBOLDO-BORGES | Descriptor: | LECT2 | Authors: | Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-29 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.402 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
7N2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2d by Molmil](/molmil-images/mine/7n2d) | MicroED structure of human zinc finger protein 292 segment (534-542) phased by ARCIMBOLDO-BORGES | Descriptor: | DIMETHYL SULFOXIDE, zinc finger protein 292 | Authors: | Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-28 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.503 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
7N2E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2e by Molmil](/molmil-images/mine/7n2e) | MicroED structure of human CPEB3 segment (154-161) straight polymorph | Descriptor: | CPEB3 | Authors: | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | Deposit date: | 2021-05-29 | Release date: | 2022-06-01 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1 Å) | Cite: | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. Acs Bio Med Chem Au, 3, 2023
|
|
1Z8F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z8f by Molmil](/molmil-images/mine/1z8f) | Guanylate Kinase Double Mutant A58C, T157C from Mycobacterium tuberculosis (Rv1389) | Descriptor: | FORMIC ACID, Guanylate kinase | Authors: | Chan, S, Sawaya, M.R, Choi, B, Zocchi, G, Perry, L.J, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | Deposit date: | 2005-03-30 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis (Rv1389) To be Published
|
|
3FOD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fod by Molmil](/molmil-images/mine/3fod) | |
3GHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ghg by Molmil](/molmil-images/mine/3ghg) | Crystal Structure of Human Fibrinogen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A knob, B knob, ... | Authors: | Doolittle, R.F, Kollman, J.M, Sawaya, M.R, Pandi, L, Riley, M. | Deposit date: | 2009-03-03 | Release date: | 2009-05-19 | Last modified: | 2023-05-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of human fibrinogen. Biochemistry, 48, 2009
|
|
3FTH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fth by Molmil](/molmil-images/mine/3fth) | |
7K3C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k3c by Molmil](/molmil-images/mine/7k3c) | SGMGGIT segment 58-64 from Keratin-8 | Descriptor: | ETHANOL, SGMGGIT segment 58-64 from the low complexity domain of Keratin-8, TRIETHYLENE GLYCOL | Authors: | Murray, K.A, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2020-09-11 | Release date: | 2021-11-10 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29, 2022
|
|
7K3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k3y by Molmil](/molmil-images/mine/7k3y) | GGYAGAS segment 52-58 from Keratin-8 | Descriptor: | GGYAGAS segment 52-58 from the low complexity domain of Keratin-8 | Authors: | Murray, K.A, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2020-09-14 | Release date: | 2021-11-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29, 2022
|
|
7K3X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k3x by Molmil](/molmil-images/mine/7k3x) | |
3HYD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hyd by Molmil](/molmil-images/mine/3hyd) | |
3I6P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3i6p by Molmil](/molmil-images/mine/3i6p) | |
3FTL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ftl by Molmil](/molmil-images/mine/3ftl) | |
3FR1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fr1 by Molmil](/molmil-images/mine/3fr1) | |
3G7W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g7w by Molmil](/molmil-images/mine/3g7w) | Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding Protein | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ... | Authors: | Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. | Deposit date: | 2009-02-11 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009
|
|
3FTK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ftk by Molmil](/molmil-images/mine/3ftk) | |