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6VNO
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor:
GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:
Leschziner, A
,
Deniston, C
,
Lahiri, I.
Deposit date:
2020-01-29
Release date:
2020-08-26
Last modified:
2020-12-23
Method:
ELECTRON MICROSCOPY (3.5 Å)
Cite:
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP8
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor:
Leucine-rich repeat serine/threonine-protein kinase 2
Authors:
Leschziner, A
,
Deniston, C
,
Lahiri, I.
Deposit date:
2020-02-01
Release date:
2020-08-26
Last modified:
2022-03-16
Method:
ELECTRON MICROSCOPY (3.5 Å)
Cite:
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP6
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor:
GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:
Leschziner, A
,
Deniston, C
,
Lahiri, I.
Deposit date:
2020-02-01
Release date:
2020-08-26
Last modified:
2020-12-23
Method:
ELECTRON MICROSCOPY (3.47 Å)
Cite:
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP7
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor:
Leucine-rich repeat serine/threonine-protein kinase 2
Authors:
Leschziner, A
,
Deniston, C
,
Lahiri, I.
Deposit date:
2020-02-01
Release date:
2020-08-26
Last modified:
2024-10-09
Method:
ELECTRON MICROSCOPY (3.5 Å)
Cite:
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
2LWE
Solution structure of mutant (T170E) second CARD of human RIG-I
Descriptor:
Probable ATP-dependent RNA helicase DDX58
Authors:
Dutta, K
,
Ferrage, F
,
Aggarwal, A.
Deposit date:
2012-07-27
Release date:
2012-10-31
Last modified:
2024-05-01
Method:
SOLUTION NMR
Cite:
Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation.
Structure, 20, 2012
2LWD
Solution structure of second CARD of human RIG-I
Descriptor:
Probable ATP-dependent RNA helicase DDX58
Authors:
Dutta, K
,
Ferrage, F
,
Aggarwal, A.
Deposit date:
2012-07-27
Release date:
2012-10-31
Last modified:
2024-05-01
Method:
SOLUTION NMR
Cite:
Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation.
Structure, 20, 2012
1AAQ
HYDROXYETHYLENE ISOSTERE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE: STRUCTURE-ACTIVITY ANALYSIS USING ENZYME KINETICS, X-RAY CRYSTALLOGRAPHY, AND INFECTED T-CELL ASSAYS
Descriptor:
HIV-1 PROTEASE, methyl N-{(4S,5S)-5-[(L-alanyl-L-alanyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-valyl-L-valinate
Authors:
Lewis, M.
Deposit date:
1992-04-13
Release date:
1994-06-22
Last modified:
2024-02-07
Method:
X-RAY DIFFRACTION (2.5 Å)
Cite:
Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays.
Biochemistry, 31, 1992
7TIT
Cardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C
Descriptor:
Myosin-binding protein C, cardiac-type, cardiac actin, ...
Authors:
Risi, C.M
,
Galkin, V.E.
Deposit date:
2022-01-14
Release date:
2022-11-23
Last modified:
2024-06-05
Method:
ELECTRON MICROSCOPY (8 Å)
Cite:
Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
7TJ7
Cardiac thin filament decorated with C1 Ig-domain and regulatory M-domain of cardiac myosin binding protein C (cMyBP-C)
Descriptor:
Myosin-binding protein C, cardiac-type, cardiac actin, ...
Authors:
Risi, C.M
,
Galkin, V.E.
Deposit date:
2022-01-14
Release date:
2022-11-23
Last modified:
2024-06-05
Method:
ELECTRON MICROSCOPY (8 Å)
Cite:
Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
7TIJ
Cardiac F-actin decorated with regulatory M-domain of cardiac myosin binding protein C
Descriptor:
Myosin-binding protein C, cardiac-type, cardiac actin
Authors:
Risi, C.M
,
Galkin, V.E.
Deposit date:
2022-01-13
Release date:
2022-11-23
Last modified:
2024-06-05
Method:
ELECTRON MICROSCOPY (8 Å)
Cite:
Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.
J.Mol.Biol., 434, 2022
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226262
數據於2024-10-16公開中