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6D6U
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BU of 6d6u by Molmil
Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and flumazenil, conformation A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Zhu, S, Noviello, C.M, Teng, J, Walsh Jr, R.M, Kim, J.J, Hibbs, R.E.
Deposit date:2018-04-22
Release date:2018-06-27
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Structure of a human synaptic GABAAreceptor.
Nature, 559, 2018
6CNJ
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BU of 6cnj by Molmil
Structure of the 2alpha3beta stiochiometry of the human Alpha4Beta2 nicotinic receptor
Descriptor: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Teng, J, Hibbs, R.E.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor.
Nature, 557, 2018
6D6T
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BU of 6d6t by Molmil
Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and flumazenil, conformation B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Zhu, S, Noviello, C.M, Teng, J, Walsh Jr, R.M, Kim, J.J, Hibbs, R.E.
Deposit date:2018-04-22
Release date:2018-06-27
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Structure of a human synaptic GABAAreceptor.
Nature, 559, 2018
8SID
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BU of 8sid by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus dehydroepiandrosterone sulfate
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Legesse, D.H, Hibbs, R.E.
Deposit date:2023-04-14
Release date:2023-08-30
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structural insights into opposing actions of neurosteroids on GABA A receptors.
Nat Commun, 14, 2023
8SI9
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BU of 8si9 by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus allopregnanolone
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Legesse, D.H, Hibbs, R.E.
Deposit date:2023-04-14
Release date:2023-08-30
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural insights into opposing actions of neurosteroids on GABA A receptors.
Nat Commun, 14, 2023
8DD3
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BU of 8dd3 by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus DMCM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Zhu, S, Hibbs, R.E.
Deposit date:2022-06-17
Release date:2022-08-17
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and dynamic mechanisms of GABA A receptor modulators with opposing activities.
Nat Commun, 13, 2022
8DD2
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BU of 8dd2 by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus Zolpidem
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Zhu, S, Hibbs, R.E.
Deposit date:2022-06-17
Release date:2022-08-17
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and dynamic mechanisms of GABA A receptor modulators with opposing activities.
Nat Commun, 13, 2022
6CNK
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BU of 6cnk by Molmil
Structure of the 3alpha2beta stiochiometry of the human Alpha4Beta2 nicotinic receptor
Descriptor: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Hibbs, R.E.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor.
Nature, 557, 2018
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數據於2024-07-17公開中

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