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6E62
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BU of 6e62 by Molmil
Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody 85RF45.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 85RF45.1 Fab heavy chain, 85RF45.1 Fab light chain, ...
Authors:Kundu, P, Semesi, A, Julien, J.P.
Deposit date:2018-07-23
Release date:2018-11-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
6E63
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BU of 6e63 by Molmil
Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody TB31F
Descriptor: GLYCEROL, Pf48/45, TB31F Fab heavy chain, ...
Authors:Kundu, P, Semesi, A, Julien, J.P.
Deposit date:2018-07-23
Release date:2018-11-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
6RCV
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BU of 6rcv by Molmil
PfRH5 bound to monoclonal antibodies R5.011 and R5.016
Descriptor: R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ...
Authors:Alanine, D.W.G, Draper, S.J, Higgins, M.K.
Deposit date:2019-04-11
Release date:2019-06-26
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (3.582 Å)
Cite:Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6RCO
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BU of 6rco by Molmil
PfRH5-binding monoclonal antibody R5.004
Descriptor: ACETATE ION, GLYCEROL, R5.004 heavy chain, ...
Authors:Alanine, D.G.W, Draper, S.J, Higgins, M.K.
Deposit date:2019-04-11
Release date:2019-06-26
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6RCU
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BU of 6rcu by Molmil
PfRH5 bound to monoclonal antibodies R5.004 and R5.016
Descriptor: R5.004 heavy chain, R5.004 light chain, R5.016 heavy chain, ...
Authors:Alanine, D.W.G, Draper, S.J, Higgins, M.K.
Deposit date:2019-04-11
Release date:2019-06-26
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (4.005 Å)
Cite:Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6RCQ
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BU of 6rcq by Molmil
PfRH5-binding monoclonal antibody R5.011
Descriptor: ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ...
Authors:Alanine, D.W.G, Draper, S.J, Higgins, M.K.
Deposit date:2019-04-11
Release date:2019-06-26
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6RCS
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BU of 6rcs by Molmil
PfRH5-binding monoclonal antibody R5.016
Descriptor: ACETATE ION, R5.016 heavy chain, R5.016 light chain, ...
Authors:Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K.
Deposit date:2019-04-11
Release date:2019-06-26
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
2TLD
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BU of 2tld by Molmil
CRYSTAL STRUCTURE OF AN ENGINEERED SUBTILISIN INHIBITOR COMPLEXED WITH BOVINE TRYPSIN
Descriptor: STREPTOMYCES SUBTILISIN INHIBITOR (SSI), TRYPSIN
Authors:Mitsui, Y, Takeuchi, Y, Nonaka, T, Nakamura, K.T.
Deposit date:1991-09-16
Release date:1992-07-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin.
Proc.Natl.Acad.Sci.USA, 89, 1992
1UE2
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BU of 1ue2 by Molmil
Crystal structure of d(GC38GAAAGCT)
Descriptor: 5'-D(*GP*(C38)P*GP*AP*AP*AP*GP*CP*T)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ...
Authors:Sunami, T, Kondo, J, Hirao, I, Watanaba, K, Miura, K, Takenaka, A.
Deposit date:2003-05-08
Release date:2004-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of d(GCGAAAGC) (hexagonal form): a base-intercalated duplex as a stable structure.
Acta Crystallogr.,Sect.D, 60, 2004
1NGQ
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BU of 1ngq by Molmil
N1G9 (IGG1-LAMBDA) FAB FRAGMENT
Descriptor: N1G9 (IGG1-LAMBDA), SULFATE ION
Authors:Mizutani, R, Satow, Y.
Deposit date:1995-06-23
Release date:1996-07-11
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate.
J.Mol.Biol., 254, 1995
5SIC
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BU of 5sic by Molmil
MOLECULAR RECOGNITION AT THE ACTIVE SITE OF SUBTILISIN BPN': CRYSTALLOGRAPHIC STUDIES USING GENETICALLY ENGINEERED PROTEINACEOUS INHIBITOR SSI (STREPTOMYCES SUBTILISIN INHIBITOR)
Descriptor: CALCIUM ION, SUBTILISIN BPN', SUBTILISIN INHIBITOR (SSI)
Authors:Mitsui, Y, Takeuchi, Y, Nakamura, K.T.
Deposit date:1991-11-18
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular recognition at the active site of subtilisin BPN': crystallographic studies using genetically engineered proteinaceous inhibitor SSI (Streptomyces subtilisin inhibitor).
Protein Eng., 4, 1991
1NGP
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BU of 1ngp by Molmil
N1G9 (IGG1-LAMBDA) FAB FRAGMENT COMPLEXED WITH (4-HYDROXY-3-NITROPHENYL) ACETATE
Descriptor: 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID, N1G9 (IGG1-LAMBDA), SULFATE ION
Authors:Mizutani, R, Satow, Y.
Deposit date:1995-06-23
Release date:1996-07-11
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate.
J.Mol.Biol., 254, 1995
6XQW
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BU of 6xqw by Molmil
Crystal Structure of MaliM03 Fab in complex with Pfmsp1-19
Descriptor: MaliM03 Fab Heavy Chain, MaliM03 Fab Light Chain, Pfmsp1-19
Authors:Singh, S, Pancera, M.
Deposit date:2020-07-10
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.991 Å)
Cite:Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites.
J.Exp.Med., 218, 2021
1UE3
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BU of 1ue3 by Molmil
Crystal structure of d(GCGAAAGC) containing hexaamminecobalt
Descriptor: 5'-D(*GP*CP*GP*AP*AP*AP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ...
Authors:Sunami, T, Kondo, J, Hirao, I, Watanabe, K, Miura, K, Takenaka, A.
Deposit date:2003-05-08
Release date:2004-01-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of d(GCGAAAGC) (hexagonal form): a base-intercalated duplex as a stable structure.
Acta Crystallogr.,Sect.D, 60, 2004
6E65
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BU of 6e65 by Molmil
Crystal structure of malaria transmission-blocking antibody TB31F
Descriptor: TB31F Fab heavy chain, TB31F Fab light chain
Authors:Kundu, P, Semesi, A, Julien, J.P.
Deposit date:2018-07-23
Release date:2018-11-28
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
6E64
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BU of 6e64 by Molmil
Crystal structure of malaria transmission-blocking antibody 85RF45.1
Descriptor: 85RF45.1 Fab heavy chain, 85RF45.1 Fab light chain
Authors:Kundu, P, Semesi, A, Julien, J.P.
Deposit date:2018-07-23
Release date:2018-11-28
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
6H5N
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BU of 6h5n by Molmil
Plasmodium falciparum Pfs48/45 C-terminal domain bound to monoclonal antibody 85RF45.1
Descriptor: Antibody 85RF45.1 heavy chain, Antibody 85RF45.1 light chain, Gametocyte surface protein P45/48
Authors:Lennartz, F, Higgins, M.K.
Deposit date:2018-07-25
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody.
Nat Commun, 9, 2018
3SSI
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BU of 3ssi by Molmil
PROTEINASE INHIBITOR SSI (STREPTOMYCES SUBTILISIN, INHIBITOR) FROM STREPTOMYCES ALBOGRISEOLUS
Descriptor: STREPTOMYCES SUBTILISIN INHIBITOR
Authors:Suzuki, T, Nonaka, T, Mitsui, Y.
Deposit date:1996-03-01
Release date:1996-08-17
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Modulation of the Protein Proteinase Inhibitor Ssi (Streptomyces Subtilisin Inhibitor)
To be Published
8GID
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BU of 8gid by Molmil
Crystal structure of a strain-transcending single-component Plasmodium falciparum AMA1-RON2L structure-based design immunogen 1 (SBD1)
Descriptor: Apical membrane antigen 1, rhoptry neck protein 2 chimera
Authors:Patel, P.N, Tolia, N.H.
Deposit date:2023-03-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8GIE
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BU of 8gie by Molmil
Crystal structure of a designed single-component Plasmodium falciparum AMA1-RON2L insertion fusion immunogen 2
Descriptor: Apical membrane antigen 1, rhoptry neck protein 2 chimera
Authors:Patel, P.N, Tolia, N.H.
Deposit date:2023-03-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8GIF
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BU of 8gif by Molmil
Crystal structure of a designed single-component Plasmodium falciparum AMA1-RON2L insertion fusion immunogen 3
Descriptor: Apical membrane antigen 1, rhoptry neck protein 2 chimera
Authors:Patel, P.N, Tolia, N.H.
Deposit date:2023-03-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8G6B
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BU of 8g6b by Molmil
Crystal structure of PfAMA1-RON2L chimera
Descriptor: Apical membrane antigen 1, rhoptry neck protein 2 chimera, SULFATE ION
Authors:Boulanger, M.J, Ramaswamy, R.
Deposit date:2023-02-14
Release date:2023-09-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies.
Nat Commun, 14, 2023
7U9W
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BU of 7u9w by Molmil
Pfs230 D1 domain in complex with 230AS-88
Descriptor: 230AS-88, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UA8
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BU of 7ua8 by Molmil
Pfs230 D1 domain in complex with 230AL-20
Descriptor: 230Al-20, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UA2
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BU of 7ua2 by Molmil
Pfs230 D1 domain in complex with 230AL-18
Descriptor: 230AL-18, Gametocyte surface protein P230, LMIV230-01
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023

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數據於2024-06-12公開中

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