6E62

Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody 85RF45.1

Summary for 6E62

Entry DOI	10.2210/pdb6e62/pdb
Descriptor	Pf48/45, 85RF45.1 Fab heavy chain, 85RF45.1 Fab light chain, ... (6 entities in total)
Functional Keywords	malaria, transmission-blocking, antigen, antibody, immune system
Biological source	Plasmodium falciparum More
Total number of polymer chains	6
Total formula weight	126180.56
Authors	Kundu, P.,Semesi, A.,Julien, J.P. (deposition date: 2018-07-23, release date: 2018-11-28, Last modification date: 2020-07-29)
Primary citation	Kundu, P.,Semesi, A.,Jore, M.M.,Morin, M.J.,Price, V.L.,Liang, A.,Li, J.,Miura, K.,Sauerwein, R.W.,King, C.R.,Julien, J.P. Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45. Nat Commun, 9:4458-4458, 2018 Cited by PubMed: 30367064 DOI: 10.1038/s41467-018-06742-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation