7CLG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7clg by Molmil](/molmil-images/mine/7clg) | |
4C7A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c7a by Molmil](/molmil-images/mine/4c7a) | Crystal structure of the Smoothened CRD, selenomethionine-labeled | Descriptor: | SMOOTHENED, SODIUM ION, ZINC ION | Authors: | Nachtergaele, S, Whalen, D.M, Mydock, L.K, Zhao, Z, Malinauskas, T, Krishnan, K, Ingham, P.W, Covey, D.F, Rohatgi, R, Siebold, C. | Deposit date: | 2013-09-20 | Release date: | 2013-11-06 | Last modified: | 2013-11-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Function of the Smoothened Extracellular Domain in Vertebrate Hedgehog Signaling Elife, 2, 2013
|
|
4C79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c79 by Molmil](/molmil-images/mine/4c79) | Crystal structure of the Smoothened CRD, native | Descriptor: | SMOOTHENED, SODIUM ION, ZINC ION | Authors: | Nachtergaele, S, Whalen, D.M, Mydock, L.K, Zhao, Z, Malinauskas, T, Krishnan, K, Ingham, P.W, Covey, D.F, Rohatgi, R, Siebold, C. | Deposit date: | 2013-09-20 | Release date: | 2013-11-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Structure and Function of the Smoothened Extracellular Domain in Vertebrate Hedgehog Signaling Elife, 2, 2013
|
|
2UUZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2uuz by Molmil](/molmil-images/mine/2uuz) | |
8IJO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ijo by Molmil](/molmil-images/mine/8ijo) | |
8IK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ik4 by Molmil](/molmil-images/mine/8ik4) | |
8IJP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ijp by Molmil](/molmil-images/mine/8ijp) | |
8IKD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ikd by Molmil](/molmil-images/mine/8ikd) | |
8IK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ik8 by Molmil](/molmil-images/mine/8ik8) | |
1X1V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x1v by Molmil](/molmil-images/mine/1x1v) | Structure Of Banana Lectin- Methyl-Alpha-Mannose Complex | Descriptor: | HEXANE-1,6-DIOL, ZINC ION, lectin, ... | Authors: | Singh, D.D, Saikrishnan, K, Kumar, P, Surolia, A, Sekar, K, Vijayan, M. | Deposit date: | 2005-04-14 | Release date: | 2005-11-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Unusual sugar specificity of banana lectin from Musa paradisiaca and its probable evolutionary origin. Crystallographic and modelling studies Glycobiology, 15, 2005
|
|
7DSU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dsu by Molmil](/molmil-images/mine/7dsu) | Structure of Mod subunit of the Type III restriction-modification enzyme Mbo45V | Descriptor: | 1,2-ETHANEDIOL, Mbo45V, SINEFUNGIN | Authors: | Ahmed, I, Chouhan, O.P, Gopinath, A, Morgan, R.D, Bhagat, K, Singh, A, Saikrishnan, K. | Deposit date: | 2021-01-02 | Release date: | 2022-01-05 | Last modified: | 2023-04-05 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of Mod subunit of the Type III restriction-modification enzyme Mbo45V To Be Published
|
|
7NFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nfu by Molmil](/molmil-images/mine/7nfu) | Crystal structure of C-terminally truncated Geobacillus thermoleovorans nucleoid occlusion protein Noc | Descriptor: | GLYCEROL, Nucleoid occlusion protein, SULFATE ION | Authors: | Jalal, A.S.B, Tran, N.T, Wu, L.J, Ramakrishnan, K, Rejzek, M, Stevenson, C.E.M, Lawson, D.M, Errington, J, Le, T.B.K. | Deposit date: | 2021-02-07 | Release date: | 2021-02-17 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc. Mol.Cell, 81, 2021
|
|
7NG0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ng0 by Molmil](/molmil-images/mine/7ng0) | Crystal structure of N- and C-terminally truncated Geobacillus thermoleovorans nucleoid occlusion protein Noc | Descriptor: | Nucleoid occlusion protein, SULFATE ION | Authors: | Jalal, A.S.B, Tran, N.T, Wu, L.J, Ramakrishnan, K, Rejzek, M, Stevenson, C.E.M, Lawson, D.M, Errington, J, Le, T.B.K. | Deposit date: | 2021-02-08 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc. Mol.Cell, 81, 2021
|
|
6HZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hz6 by Molmil](/molmil-images/mine/6hz6) | Structure of McrBC without DNA binding domains (Class 2) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
|
|
6HZ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hz5 by Molmil](/molmil-images/mine/6hz5) | Structure of McrBC without DNA binding domains (Class 1) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
|
|
6HZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hz8 by Molmil](/molmil-images/mine/6hz8) | Structure of McrBC without DNA binding domains (Class 4) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
|
|
6HZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hz7 by Molmil](/molmil-images/mine/6hz7) | Structure of McrBC without DNA binding domains (Class 3) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
|
|
6HZ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hz9 by Molmil](/molmil-images/mine/6hz9) | Structure of McrBC without DNA binding domains (Class 5) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
|
|
6HZ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hz4 by Molmil](/molmil-images/mine/6hz4) | Structure of McrBC without DNA binding domains (one half of the full complex) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
|
|
4XQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xqk by Molmil](/molmil-images/mine/4xqk) | |
2UV1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2uv1 by Molmil](/molmil-images/mine/2uv1) | |
5SSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ssx by Molmil](/molmil-images/mine/5ssx) | |
5SSY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ssy by Molmil](/molmil-images/mine/5ssy) | |
4Y14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y14 by Molmil](/molmil-images/mine/4y14) | Structure of protein tyrosine phosphatase 1B complexed with inhibitor (PTP1B:CPT157633) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-bromo-4-[difluoro(phosphono)methyl]-N-methyl-Nalpha-(methylsulfonyl)-L-phenylalaninamide, CHLORIDE ION, ... | Authors: | Choy, M.S, Connors, C, Page, R, Peti, W. | Deposit date: | 2015-02-06 | Release date: | 2015-08-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J.Clin.Invest., 125, 2015
|
|
7ZI0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zi0 by Molmil](/molmil-images/mine/7zi0) | Structure of human Smoothened in complex with cholesterol and SAG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide, CHOLESTEROL, ... | Authors: | Byrne, E.F.X, Woolley, R.E, Ansell, B, Sansom, M.S.P, Newstead, S, Siebold, C. | Deposit date: | 2022-04-07 | Release date: | 2022-06-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain. Sci Adv, 8, 2022
|
|