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5FIR
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BU of 5fir by Molmil
Crystal structure of C. elegans XRN2 in complex with the XRN2-binding domain of PAXT-1
Descriptor: 5'-3' EXORIBONUCLEASE 2 HOMOLOG, PAXT-1, SULFATE ION
Authors:Richter, H, Katic, I, Gut, H, Grosshans, H.
Deposit date:2015-10-02
Release date:2016-01-20
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.836 Å)
Cite:Structural Basis and Function of Xrn2-Binding by Xtb Domains
Nat.Struct.Mol.Biol., 23, 2016
6FQ1
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BU of 6fq1 by Molmil
Crystal structure of the RRM12 domain of IMP3
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-02-12
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
6FQR
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BU of 6fqr by Molmil
Crystal structure of IMP3 RRM12 in complex with RNA (CCCC)
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 3, RNA CCCC
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-02-14
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
6GX6
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BU of 6gx6 by Molmil
Crystal structure of IMP3 RRM12 in complex with RNA (ACAC)
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3, PHOSPHATE ION, ...
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-06-26
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
6I3H
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BU of 6i3h by Molmil
Crystal structure of influenza A virus M1 N-terminal domain (G18A mutation)
Descriptor: Matrix protein 1, PHOSPHATE ION
Authors:Miyake, Y, Keusch, J.J, Decamps, L, Ho-Xuan, H, Iketani, S, Gut, H, Kutay, U, Helenius, A, Yamauchi, Y.
Deposit date:2018-11-06
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Influenza virus uses transportin 1 for vRNP debundling during cell entry.
Nat Microbiol, 4, 2019
5M1X
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BU of 5m1x by Molmil
Crystal structure of S. cerevisiae Rfa1 N-OB domain mutant (K45E)
Descriptor: Replication factor A protein 1
Authors:Seeber, A, Hegnauer, A.M, Hustedt, N, Deshpande, I, Poli, J, Eglinger, J, Pasero, P, Gut, H, Shinohara, M, Hopfner, K.P, Shimada, K, Gasser, S.M.
Deposit date:2016-10-11
Release date:2016-12-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together.
Mol. Cell, 64, 2016
6QSZ
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BU of 6qsz by Molmil
Crystal structure of the Sir4 H-BRCT domain in complex with Esc1 pS1450 peptide
Descriptor: CHLORIDE ION, Regulatory protein SIR4, Silent chromatin protein ESC1
Authors:Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M, Gut, H.
Deposit date:2019-02-22
Release date:2019-09-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
Embo J., 38, 2019
5G0H
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BU of 5g0h by Molmil
Crystal structure of Danio rerio HDAC6 CD2 in complex with (S)- trichostatin A
Descriptor: 1,2-ETHANEDIOL, HDAC6, POTASSIUM ION, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0F
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BU of 5g0f by Molmil
Crystal structure of Danio rerio HDAC6 ZnF-UBP domain
Descriptor: GLYCINE, HDAC6, NICKEL (II) ION, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0J
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BU of 5g0j by Molmil
Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker intact) in complex with Nexturastat A
Descriptor: CHLORIDE ION, HDAC6, NEXTURASTAT A, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
6RR0
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BU of 6rr0 by Molmil
Crystal structure of the Sir4 H-BRCT domain in complex with Ubp10 pT123 peptide
Descriptor: CHLORIDE ION, Regulatory protein SIR4, Ubiquitin carboxyl-terminal hydrolase 10
Authors:Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M, Gut, H.
Deposit date:2019-05-16
Release date:2019-09-18
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
Embo J., 38, 2019
6RRV
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BU of 6rrv by Molmil
Crystal structure of the Sir4 H-BRCT domain
Descriptor: BROMIDE ION, CHLORIDE ION, Regulatory protein SIR4
Authors:Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M, Gut, H.
Deposit date:2019-05-20
Release date:2019-09-18
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
Embo J., 38, 2019
5G0I
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BU of 5g0i by Molmil
Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker cleaved) in complex with Nexturastat A
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, HDAC6, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0G
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BU of 5g0g by Molmil
Crystal structure of Danio rerio HDAC6 CD1 in complex with trichostatin A
Descriptor: CHLORIDE ION, HDAC6, SODIUM ION, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
4BJT
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BU of 4bjt by Molmil
Crystal structure of the Rap1 C-terminal domain (Rap1-RCT) in complex with the Rap1 binding module of Rif1 (Rif1-RBM)
Descriptor: 1,2-ETHANEDIOL, DNA-BINDING PROTEIN RAP1, TELOMERE LENGTH REGULATOR PROTEIN RIF1
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-19
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJ6
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BU of 4bj6 by Molmil
Crystal structure Rif2 in complex with the C-terminal domain of Rap1 (Rap1-RCT)
Descriptor: DNA-BINDING PROTEIN RAP1, RAP1-INTERACTING FACTOR 2, SULFATE ION
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-16
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJS
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BU of 4bjs by Molmil
Crystal structure of the Rif1 C-terminal domain (Rif1-CTD) from Saccharomyces cerevisiae
Descriptor: TELOMERE LENGTH REGULATOR PROTEIN RIF1
Authors:Bunker, R.D, Shi, T, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-19
Release date:2013-06-19
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJ1
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BU of 4bj1 by Molmil
Crystal structure of Saccharomyces cerevisiae RIF2
Descriptor: CHLORIDE ION, PROTEIN RIF2
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-15
Release date:2013-06-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4A0A
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BU of 4a0a by Molmil
Structure of hsDDB1-drDDB2 bound to a 16 bp CPD-duplex (pyrimidine at D-1 position) at 3.6 A resolution (CPD 3)
Descriptor: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*DGP)-3', CALCIUM ION, ...
Authors:Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
4A09
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BU of 4a09 by Molmil
Structure of hsDDB1-drDDB2 bound to a 15 bp CPD-duplex (purine at D-1 position) at 3.1 A resolution (CPD 2)
Descriptor: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*GP)-3', CALCIUM ION, ...
Authors:Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
4AP5
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BU of 4ap5 by Molmil
Crystal structure of human POFUT2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ...
Authors:Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H.
Deposit date:2012-03-30
Release date:2012-08-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation.
Embo J., 31, 2012
4AE8
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BU of 4ae8 by Molmil
Crystal structure of human THEM4
Descriptor: THIOESTERASE SUPERFAMILY MEMBER 4
Authors:Zhuravleva, E, Gut, H, Hynx, D, Marcellin, D, Bleck, C.K.E, Genoud, C, Cron, P, Keusch, J.J, Dummler, B, Degli Esposti, M, Hemmings, B.A.
Deposit date:2012-01-09
Release date:2012-07-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.594 Å)
Cite:Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
4BJ5
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BU of 4bj5 by Molmil
Crystal structure of Rif2 in complex with the C-terminal domain of Rap1 (Rap1-RCT)
Descriptor: DNA-BINDING PROTEIN RAP1, PROTEIN RIF2, SULFATE ION
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-16
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4A11
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BU of 4a11 by Molmil
Structure of the hsDDB1-hsCSA complex
Descriptor: DNA DAMAGE-BINDING PROTEIN 1, DNA EXCISION REPAIR PROTEIN ERCC-8
Authors:Bohm, K, Scrima, A, Fischer, E.S, Gut, H, Thomae, N.H.
Deposit date:2011-09-13
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4A0K
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BU of 4a0k by Molmil
STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX
Descriptor: 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ...
Authors:Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (5.93 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011

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數據於2024-10-30公開中

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