5M88
 
 | | Spliceosome component | | Descriptor: | Core | | Authors: | Moura, T.R, Pena, V. | | Deposit date: | 2016-10-28 | | Release date: | 2018-02-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
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5CKI
 | | Crystal structure of 9DB1* deoxyribozyme (Cobalt hexammine soaked crystals) | | Descriptor: | COBALT (II) ION, DNA (44-MER), MAGNESIUM ION, ... | | Authors: | Ponce-Salvatierra, A, Hoebartner, C, Pena, V. | | Deposit date: | 2015-07-15 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.985 Å) | | Cite: | Crystal structure of a DNA catalyst.
Nature, 529, 2016
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5CKK
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4PJ3
 | | Structural insight into the function and evolution of the spliceosomal helicase Aquarius, Structure of Aquarius in complex with AMPPNP | | Descriptor: | Intron-binding protein aquarius, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | De, I, Bessonov, S, Hofele, R, dos Santos, K.F, Will, C.L, Urlaub, H, Luhrmann, R, Pena, V. | | Deposit date: | 2014-05-11 | | Release date: | 2015-01-21 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes.
Nat.Struct.Mol.Biol., 22, 2015
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6EN4
 | | SF3b core in complex with a splicing modulator | | Descriptor: | PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... | | Authors: | Cretu, C, Pena, V. | | Deposit date: | 2017-10-04 | | Release date: | 2018-06-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.08 Å) | | Cite: | Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds.
Mol. Cell, 70, 2018
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4F92
 | | Brr2 Helicase Region S1087L | | Descriptor: | SULFANILAMIDE, U5 small nuclear ribonucleoprotein 200 kDa helicase | | Authors: | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | | Deposit date: | 2012-05-18 | | Release date: | 2012-10-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.662 Å) | | Cite: | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4F91
 | | Brr2 Helicase Region | | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase | | Authors: | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | | Deposit date: | 2012-05-18 | | Release date: | 2012-10-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.697 Å) | | Cite: | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4F93
 | | Brr2 Helicase Region S1087L, Mg-ATP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | | Deposit date: | 2012-05-18 | | Release date: | 2012-10-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2MJF
 | | Solution structure of the complex between the yeast Rsa1 and Hit1 proteins | | Descriptor: | Protein HIT1, Ribosome assembly 1 protein | | Authors: | Quinternet, M, Roth, B, Back, R, Jacquemin, C, Manival, X. | | Deposit date: | 2014-01-08 | | Release date: | 2014-09-10 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction.
Nucleic Acids Res., 42, 2014
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5LQW
 | | yeast activated spliceosome | | Descriptor: | Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ... | | Authors: | Rauhut, R, Luehrmann, R. | | Deposit date: | 2016-08-17 | | Release date: | 2016-10-05 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Science, 6306, 2016
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3TP2
 | | Crystal Structure of the Splicing Factor Cwc2 from yeast | | Descriptor: | Pre-mRNA-splicing factor CWC2, SODIUM ION, ZINC ION | | Authors: | Schmitzova, J. | | Deposit date: | 2011-09-07 | | Release date: | 2012-03-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein.
Embo J., 31, 2012
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