4PJ3
Structural insight into the function and evolution of the spliceosomal helicase Aquarius, Structure of Aquarius in complex with AMPPNP
Summary for 4PJ3
Entry DOI | 10.2210/pdb4pj3/pdb |
Related | 4PJ4 |
Descriptor | Intron-binding protein aquarius, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | rna helicase, pre-mrna splicing, rna binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : O60306 |
Total number of polymer chains | 1 |
Total formula weight | 173110.18 |
Authors | De, I.,Bessonov, S.,Hofele, R.,dos Santos, K.F.,Will, C.L.,Urlaub, H.,Luhrmann, R.,Pena, V. (deposition date: 2014-05-11, release date: 2015-01-21, Last modification date: 2023-12-27) |
Primary citation | De, I.,Bessonov, S.,Hofele, R.,Dos Santos, K.,Will, C.L.,Urlaub, H.,Luhrmann, R.,Pena, V. The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nat.Struct.Mol.Biol., 22:138-144, 2015 Cited by PubMed: 25599396DOI: 10.1038/nsmb.2951 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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