3TWF
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![BU of 3twf by Molmil](/molmil-images/mine/3twf) | Crystal structure of the de novo designed fluorinated peptide alpha4F3a | Descriptor: | ACETYL GROUP, SODIUM ION, TRIETHYLENE GLYCOL, ... | Authors: | Buer, B.C, Meagher, J.L, Stuckey, J.A, Marsh, E.N.G. | Deposit date: | 2011-09-21 | Release date: | 2012-03-14 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural basis for the enhanced stability of highly fluorinated proteins. Proc.Natl.Acad.Sci.USA, 109, 2012
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3UAR
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![BU of 3uar by Molmil](/molmil-images/mine/3uar) | Crystal structure of glutathione transferase (TARGET EFI-501774) from methylococcus capsulatus str. bath with gsh bound | Descriptor: | GLUTATHIONE, GLYCEROL, Glutathione S-transferase | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2011-10-21 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Glutathione S-Transferase from Methylococcus Capsulatus To be Published
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3UBL
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![BU of 3ubl by Molmil](/molmil-images/mine/3ubl) | Crystal structure of glutathione transferase (TARGET EFI-501770) from leptospira interrogans with gsh bound | Descriptor: | CHLORIDE ION, GLUTATHIONE, GLYCEROL, ... | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2011-10-24 | Release date: | 2011-11-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Glutathione S-Transferase from Leptospira Interrogans To be Published
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4OGC
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![BU of 4ogc by Molmil](/molmil-images/mine/4ogc) | Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | Descriptor: | ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ... | Authors: | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | Deposit date: | 2014-01-15 | Release date: | 2014-02-12 | Last modified: | 2014-03-26 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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4OVS
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![BU of 4ovs by Molmil](/molmil-images/mine/4ovs) | CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM SULFUROSPIRILLUM DELEYIANUM DSM 6946 (Sdel_0447), TARGET EFI-510309, WITH BOUND SUCCINATE | Descriptor: | CHLORIDE ION, SUCCINIC ACID, TRAP dicarboxylate transporter, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-12-13 | Release date: | 2014-01-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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4OY5
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![BU of 4oy5 by Molmil](/molmil-images/mine/4oy5) | 0.89 Angstrom resolution crystal structure of (Gly-Pro-Hyp)10 | Descriptor: | Collagen | Authors: | Suzuki, H, Mahapatra, D, Steel, P.J, Dyer, J, Dobson, R.C.J, Gerrard, J.A, Valery, C. | Deposit date: | 2014-02-10 | Release date: | 2015-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (0.89 Å) | Cite: | Sub-angstrom structure of the collagen model peptide (GPO)10 shows a hydrated triple helix with pitch variation and two proline ring conformations To Be Published
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4ODG
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![BU of 4odg by Molmil](/molmil-images/mine/4odg) | Crystal structure of Staphylococcal nuclease variant V23I/V66I/V74I/V99I at cryogenic temperature | Descriptor: | CALCIUM ION, PHOSPHATE ION, THYMIDINE-3',5'-DIPHOSPHATE, ... | Authors: | Caro, J.A, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | Deposit date: | 2014-01-10 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Pressure effects in proteins To be Published
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4O8R
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![BU of 4o8r by Molmil](/molmil-images/mine/4o8r) | Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate | Descriptor: | 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, Orotidine 5'-phosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Chan, K.K, Gerlt, J.A, Almo, S.C. | Deposit date: | 2013-12-29 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate To be Published
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1I0Z
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![BU of 1i0z by Molmil](/molmil-images/mine/1i0z) | HUMAN HEART L-LACTATE DEHYDROGENASE H CHAIN, TERNARY COMPLEX WITH NADH AND OXAMATE | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-LACTATE DEHYDROGENASE H CHAIN, OXAMIC ACID | Authors: | Read, J.A, Winter, V.J, Eszes, C.M, Sessions, R.B, Brady, R.L. | Deposit date: | 2001-01-30 | Release date: | 2001-03-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase. Proteins, 43, 2001
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4OGE
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![BU of 4oge by Molmil](/molmil-images/mine/4oge) | Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | Descriptor: | HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ... | Authors: | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | Deposit date: | 2014-01-15 | Release date: | 2014-02-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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1I6Q
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![BU of 1i6q by Molmil](/molmil-images/mine/1i6q) | Formation of a protein intermediate and its trapping by the simultaneous crystallization process: Crystal structure of an iron-saturated intermediate in the FE3+ binding pathway of camel lactoferrin at 2.7 resolution | Descriptor: | CARBONATE ION, FE (III) ION, LACTOFERRIN | Authors: | Khan, J.A, Kumar, P, Srinivasan, A, Singh, T.P. | Deposit date: | 2001-03-03 | Release date: | 2001-11-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Protein intermediate trapped by the simultaneous crystallization process. Crystal structure of an iron-saturated intermediate in the Fe3+ binding pathway of camel lactoferrin at 2.7 a resolution. J.Biol.Chem., 276, 2001
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1I7B
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![BU of 1i7b by Molmil](/molmil-images/mine/1i7b) | HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COVALENTLY BOUND S-ADENOSYLMETHIONINE METHYL ESTER | Descriptor: | 1,4-DIAMINOBUTANE, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN, ... | Authors: | Tolbert, W.D, Ekstrom, J.L, Mathews, I.I, Secrist III, J.A, Pegg, A.E, Ealick, S.E. | Deposit date: | 2001-03-08 | Release date: | 2001-08-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase. Biochemistry, 40, 2001
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4OUO
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![BU of 4ouo by Molmil](/molmil-images/mine/4ouo) | anti-Bla g 1 scFv | Descriptor: | CHLORIDE ION, SULFATE ION, anti Bla g 1 scFv | Authors: | Mueller, G.A, Ankney, J.A, Glesner, J, Khurana, T, Edwards, L.L, Pedersen, L.C, Perera, L, Slater, J.E, Pomes, A, London, R.E. | Deposit date: | 2014-02-18 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Characterization of an anti-Bla g 1 scFv: Epitope mapping and cross-reactivity. Mol.Immunol., 59, 2014
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4OXB
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![BU of 4oxb by Molmil](/molmil-images/mine/4oxb) | |
4O92
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![BU of 4o92 by Molmil](/molmil-images/mine/4o92) | Crystal structure of a Glutathione S-transferase from Pichia kudriavzevii (Issatchenkia orientalis), target EFI-501747 | Descriptor: | Glutathione S-transferase, SULFATE ION | Authors: | Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Glenn, A.S, Chowdhury, S, Evans, B, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Attonito, J.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-12-31 | Release date: | 2014-01-15 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Crystal structure of a Glutathione S-transferase from Pichia kudriavzevii (Issatchenkia orientalis), target EFI-501747 TO BE PUBLISHED
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4OVT
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![BU of 4ovt by Molmil](/molmil-images/mine/4ovt) | CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM OCHROBACTERIUM ANTHROPI (Oant_3902), TARGET EFI-510153, WITH BOUND L-FUCONATE | Descriptor: | 6-deoxy-L-galactonic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-12-14 | Release date: | 2014-01-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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4OWZ
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![BU of 4owz by Molmil](/molmil-images/mine/4owz) | |
4OAN
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![BU of 4oan by Molmil](/molmil-images/mine/4oan) | Crystal structure of a TRAP periplasmic solute binding protein from rhodopseudomonas palustris HaA2 (RPB_2686), TARGET EFI-510221, with density modeled as (S)-2-hydroxy-2-methyl-3-oxobutanoate ((S)-2-Acetolactate) | Descriptor: | (2S)-2-hydroxy-2-methyl-3-oxobutanoic acid, CHLORIDE ION, GLYCEROL, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-01-05 | Release date: | 2014-01-22 | Last modified: | 2015-02-25 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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4OX9
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![BU of 4ox9 by Molmil](/molmil-images/mine/4ox9) | Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit | Descriptor: | 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ... | Authors: | Dunkle, J.A, Conn, G.L, Dunham, C.M. | Deposit date: | 2014-02-04 | Release date: | 2014-04-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.8035 Å) | Cite: | Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proc.Natl.Acad.Sci.USA, 111, 2014
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1II8
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![BU of 1ii8 by Molmil](/molmil-images/mine/1ii8) | Crystal structure of the P. furiosus Rad50 ATPase domain | Descriptor: | PHOSPHATE ION, Rad50 ABC-ATPase | Authors: | Hopfner, K.-P, Karcher, A, Craig, L, Woo, T.T, Carney, J.P, Tainer, J.A. | Deposit date: | 2001-04-20 | Release date: | 2001-05-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell(Cambridge,Mass.), 105, 2001
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1IKE
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![BU of 1ike by Molmil](/molmil-images/mine/1ike) | Crystal Structure of Nitrophorin 4 from Rhodnius Prolixus Complexed with Histamine at 1.5 A Resolution | Descriptor: | HISTAMINE, Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Roberts, S.A, Weichsel, A, Qiu, Y, Shelnutt, J.A, Walker, F.A, Montfort, W.R. | Deposit date: | 2001-05-03 | Release date: | 2001-10-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Ligand-induced heme ruffling and bent no geometry in ultra-high-resolution structures of nitrophorin 4. Biochemistry, 40, 2001
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1J7Q
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![BU of 1j7q by Molmil](/molmil-images/mine/1j7q) | Solution structure and backbone dynamics of the defunct EF-hand domain of Calcium Vector Protein | Descriptor: | Calcium Vector Protein | Authors: | Theret, I, Baladi, S, Cox, J.A, Gallay, J, Sakamoto, H, Craescu, C.T. | Deposit date: | 2001-05-18 | Release date: | 2001-06-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of the defunct domain of calcium vector protein. Biochemistry, 40, 2001
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1J0R
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![BU of 1j0r by Molmil](/molmil-images/mine/1j0r) | Crystal structure of the replication termination protein mutant C110S | Descriptor: | replication termination protein | Authors: | Vivian, J.P, Hastings, A.F, Duggin, I.G, Wake, R.G, Wilce, M.C.J, Wilce, J.A. | Deposit date: | 2002-11-20 | Release date: | 2003-11-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The impact of single cysteine residue mutations on the replication terminator protein Biochem.Biophys.Res.Commun., 310, 2003
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1IN7
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![BU of 1in7 by Molmil](/molmil-images/mine/1in7) | THERMOTOGA MARITIMA RUVB R170A | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, HOLLIDAY JUNCTION DNA HELICASE RUVB | Authors: | Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A. | Deposit date: | 2001-05-12 | Release date: | 2001-08-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanism of the RuvB Holliday junction branch migration motor. J.Mol.Biol., 311, 2001
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1IN6
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![BU of 1in6 by Molmil](/molmil-images/mine/1in6) | THERMOTOGA MARITIMA RUVB K64R MUTANT | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ... | Authors: | Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A. | Deposit date: | 2001-05-12 | Release date: | 2001-08-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and mechanism of the RuvB Holliday junction branch migration motor. J.Mol.Biol., 311, 2001
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