3R7W
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![BU of 3r7w by Molmil](/molmil-images/mine/3r7w) | Crystal Structure of Gtr1p-Gtr2p complex | Descriptor: | GTP-binding protein GTR1, GTP-binding protein GTR2, MAGNESIUM ION, ... | Authors: | Gong, R, Li, L, Liu, Y, Wang, P, Yang, H, Wang, L, Cheng, J, Guan, K.L, Xu, Y. | Deposit date: | 2011-03-23 | Release date: | 2011-08-24 | Last modified: | 2013-06-19 | Method: | X-RAY DIFFRACTION (2.773 Å) | Cite: | Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation Genes Dev., 25, 2011
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2WYL
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![BU of 2wyl by Molmil](/molmil-images/mine/2wyl) | Apo structure of a metallo-b-lactamase | Descriptor: | FORMYL GROUP, GLYCEROL, L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG | Authors: | Garces, F, Fernandez, F.J, Penya-Soler, E, Aguilar, J, Baldoma, L, Coll, M, Badia, J, Vega, M.C. | Deposit date: | 2009-11-16 | Release date: | 2010-04-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Molecular Architecture of the Mn(2+)Dependent Lactonase Ulag Reveals an Rnase-Like Metallo-Beta-Lactamase Fold and a Novel Quaternary Structure. J.Mol.Biol., 398, 2010
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6EFY
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![BU of 6efy by Molmil](/molmil-images/mine/6efy) | Crystal Structure of DIP-Alpha Ig1-3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein alpha, isoform A, ... | Authors: | Cosmanescu, F, Shapiro, L. | Deposit date: | 2018-08-17 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron, 100, 2018
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1EZZ
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![BU of 1ezz by Molmil](/molmil-images/mine/1ezz) | |
1F2T
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![BU of 1f2t by Molmil](/molmil-images/mine/1f2t) | Crystal Structure of ATP-Free RAD50 ABC-ATPase | Descriptor: | RAD50 ABC-ATPASE | Authors: | Hopfner, K.P, Karcher, A, Shin, D.S, Craig, L. | Deposit date: | 2000-05-29 | Release date: | 2000-08-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. Cell(Cambridge,Mass.), 101, 2000
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5XPW
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![BU of 5xpw by Molmil](/molmil-images/mine/5xpw) | Structure of amphioxus IgVJ-C2 molecule | Descriptor: | amphioxus IgVJ-C2 | Authors: | Chen, R, Qi, J, Zhang, N, Zhang, L, Yao, S, Wu, Y, Jiang, B, Wang, Z, Yuan, H, Zhang, Q, Xia, C. | Deposit date: | 2017-06-05 | Release date: | 2018-04-18 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Discovery and Analysis of Invertebrate IgVJ-C2 Structure from Amphioxus Provides Insight into the Evolution of the Ig Superfamily. J. Immunol., 200, 2018
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3T3O
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![BU of 3t3o by Molmil](/molmil-images/mine/3t3o) | Molecular basis for the recognition and cleavage of RNA (CUGG) by the bifunctional 5'-3' exo/endoribonuclease RNase J | Descriptor: | GLYCEROL, Metal dependent hydrolase, O2'methyl-RNA, ... | Authors: | Dorleans, A, Li de la Sierra-Gallay, I, Piton, J, Zig, L, Gilet, L, Putzer, H, Condon, C. | Deposit date: | 2011-07-25 | Release date: | 2011-10-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular Basis for the Recognition and Cleavage of RNA by the Bifunctional 5'-3' Exo/Endoribonuclease RNase J. Structure, 19, 2011
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2X5O
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![BU of 2x5o by Molmil](/molmil-images/mine/2x5o) | Discovery of Novel 5-Benzylidenerhodanine- and 5-Benzylidene- thiazolidine-2,4-dione Inhibitors of MurD Ligase | Descriptor: | AZIDE ION, CHLORIDE ION, N-({3-[({4-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-D-GLUTAMIC ACID, ... | Authors: | Zidar, N, Tomasic, T, Sink, R, Rupnik, V, Kovac, A, Turk, S, Contreras-Martel, C, Dessen, A, Blanot, D, Gobec, S, Zega, A, Peterlin-Masic, L, Kikelja, D. | Deposit date: | 2010-02-10 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase. J. Med. Chem., 53, 2010
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1F4M
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![BU of 1f4m by Molmil](/molmil-images/mine/1f4m) | P3(2) CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD. | Descriptor: | CALCIUM ION, ROP ALA2ILE2-6 | Authors: | Willis, M.A, Bishop, B, Regan, L, Brunger, A.T. | Deposit date: | 2000-06-08 | Release date: | 2001-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core. Structure Fold.Des., 8, 2000
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2MGV
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![BU of 2mgv by Molmil](/molmil-images/mine/2mgv) | NMR structure of PASTA domain of PonA2 from Mycobacterium tuberculosis | Descriptor: | Bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2 | Authors: | Calvanese, L, Falcigno, L, Maglione, C, Marasco, D, Ruggiero, A, Squeglia, F, Berisio, R, D'Auria, G. | Deposit date: | 2013-11-11 | Release date: | 2013-12-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis. Biopolymers, 101, 2014
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3O9L
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![BU of 3o9l by Molmil](/molmil-images/mine/3o9l) | Design and optimisation of new piperidines as renin inhibitors | Descriptor: | (3R,4S)-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropyl-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | Authors: | Corminboeuf, O, Bezencon, O, Grisostomi, C, Remen, L, Richard-Bildstein, S, Bur, D, Prade, L, Hess, P, Strickner, P, Treiber, A. | Deposit date: | 2010-08-04 | Release date: | 2011-03-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Design and optimization of new piperidines as renin inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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1EZL
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![BU of 1ezl by Molmil](/molmil-images/mine/1ezl) | CRYSTAL STRUCTURE OF THE DISULPHIDE BOND-DEFICIENT AZURIN MUTANT C3A/C26A: HOW IMPORTANT IS THE S-S BOND FOR FOLDING AND STABILITY? | Descriptor: | AZURIN, COPPER (II) ION | Authors: | Bonander, N, Leckner, J, Guo, H, Karlsson, B.G, Sjolin, L. | Deposit date: | 2000-05-11 | Release date: | 2000-08-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the disulfide bond-deficient azurin mutant C3A/C26A: how important is the S-S bond for folding and stability? Eur.J.Biochem., 267, 2000
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1F4N
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![BU of 1f4n by Molmil](/molmil-images/mine/1f4n) | C2 CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ROP ALA2ILE2-6 | Authors: | Willis, M.A, Bishop, B, Regan, L, Brunger, A.T. | Deposit date: | 2000-06-08 | Release date: | 2001-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core. Structure Fold.Des., 8, 2000
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3TC6
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![BU of 3tc6 by Molmil](/molmil-images/mine/3tc6) | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR63. | Descriptor: | DI(HYDROXYETHYL)ETHER, Indole-3-glycerol phosphate synthase, PHOSPHATE ION | Authors: | Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-08-08 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. J.Mol.Biol., 426, 2014
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3TCO
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![BU of 3tco by Molmil](/molmil-images/mine/3tco) | Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability | Descriptor: | 1,2-ETHANEDIOL, Thioredoxin (TrxA-1) | Authors: | Esposito, L, Ruggiero, A, Masullo, M, Ruocco, M.R, Lamberti, A, Arcari, P, Zagari, A, Vitagliano, L. | Deposit date: | 2011-08-09 | Release date: | 2011-11-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability. J.Struct.Biol., 177, 2012
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1EZK
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![BU of 1ezk by Molmil](/molmil-images/mine/1ezk) | Crystal structure of recombinant tryparedoxin I | Descriptor: | TRYPAREDOXIN I | Authors: | Hofmann, B, Guerrero, S.A, Kalisz, H.M, Menge, U, Nogoceke, E, Montemartini, M, Singh, M, Flohe, L, Hecht, H.J. | Deposit date: | 2000-05-11 | Release date: | 2000-05-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of tryparedoxins revealing interaction with trypanothione. Biol.Chem., 382, 2001
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1F1X
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![BU of 1f1x by Molmil](/molmil-images/mine/1f1x) | CRYSTAL STRUCTURE OF HOMOPROTOCATECHUATE 2,3-DIOXYGENASE FROM BREVIBACTERIUM FUSCUM | Descriptor: | HOMOPROTOCATECHUATE 2,3-DIOXYGENASE, HYDRATED FE | Authors: | Vetting, M.W, Lipscomb, J.D, Wackett, L.P, Que Jr, L, Ohlendorf, D.H. | Deposit date: | 2000-05-20 | Release date: | 2003-06-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J.Bacteriol., 186, 2004
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1F22
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![BU of 1f22 by Molmil](/molmil-images/mine/1f22) | A PROTON-NMR INVESTIGATION OF THE FULLY REDUCED CYTOCHROME C7 FROM DESULFUROMONAS ACETOXIDANS. COMPARISON BETWEEN THE REDUCED AND THE OXIDIZED FORMS. | Descriptor: | CYTOCHROME C7, HEME C | Authors: | Assfalg, M, Banci, L, Bertini, I, Bruschi, M, Giudici-Orticoni, M.T. | Deposit date: | 2000-05-23 | Release date: | 2000-06-21 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | A proton-NMR investigation of the fully reduced cytochrome c7 from Desulfuromonas acetoxidans. Comparison between the reduced and the oxidized forms. Eur.J.Biochem., 266, 1999
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4ELC
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![BU of 4elc by Molmil](/molmil-images/mine/4elc) | Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134 mutant with MTSEA modified Cys-165 | Descriptor: | (2S)-2-hydroxybutanedioic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Botulinum neurotoxin A light chain, ... | Authors: | Stura, E.A, Vera, L, Ptchelkine, D, Bakirci, H, Garcia, S, Dive, V. | Deposit date: | 2012-04-10 | Release date: | 2012-08-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165. J.Biol.Chem., 287, 2012
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4I4O
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![BU of 4i4o by Molmil](/molmil-images/mine/4i4o) | BEL beta-trefoil apo crystal form 1 | Descriptor: | BEL beta-trefoil, GLYCEROL, SULFATE ION | Authors: | Bovi, M, Cenci, L, Perduca, M, Capaldi, S, Carrizo, M.E, Civiero, L, Chiarelli, L.R, Galliano, M, Monaco, H.L. | Deposit date: | 2012-11-28 | Release date: | 2013-04-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | BEL {beta}-trefoil: A novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms. Glycobiology, 23, 2013
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4I4X
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![BU of 4i4x by Molmil](/molmil-images/mine/4i4x) | BEL beta-trefoil complex with T-Antigen disaccharide | Descriptor: | BEL beta-trefoil, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | Authors: | Bovi, M, Cenci, L, Perduca, M, Capaldi, S, Carrizo, M.E, Civiero, L, Chiarelli, L.R, Galliano, M, Monaco, H.L. | Deposit date: | 2012-11-28 | Release date: | 2013-04-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | BEL {beta}-trefoil: A novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms. Glycobiology, 23, 2013
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1F08
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![BU of 1f08 by Molmil](/molmil-images/mine/1f08) | CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF THE REPLICATION INITIATION PROTEIN E1 FROM PAPILLOMAVIRUS | Descriptor: | BROMIDE ION, REPLICATION PROTEIN E1 | Authors: | Enemark, E.J, Chen, G, Vaughn, D.E, Stenlund, A, Joshua-Tor, L. | Deposit date: | 2000-05-15 | Release date: | 2001-05-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus. Mol.Cell, 6, 2000
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3ODT
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![BU of 3odt by Molmil](/molmil-images/mine/3odt) | Crystal structure of WD40 beta propeller domain of Doa1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Protein DOA1 | Authors: | Pashkova, N, Gakhar, L, Winistorfer, S.C, Yu, L, Ramaswamy, S, Piper, R.C. | Deposit date: | 2010-08-11 | Release date: | 2010-12-01 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | WD40 Repeat Propellers Define a Ubiquitin-Binding Domain that Regulates Turnover of F Box Proteins. Mol.Cell, 40, 2010
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3O47
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![BU of 3o47 by Molmil](/molmil-images/mine/3o47) | Crystal structure of ARFGAP1-ARF1 fusion protein | Descriptor: | ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Wang, H, Tong, Y, Nedyalkova, L, Tempel, W, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-07-26 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of ARFGAP1-ARF1 fusion protein to be published
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4I4Q
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![BU of 4i4q by Molmil](/molmil-images/mine/4i4q) | BEL beta-trefoil apo crystal form 3 | Descriptor: | BEL-beta trefoil, GLYCEROL | Authors: | Bovi, M, Cenci, L, Perduca, M, Capaldi, S, Carrizo, M.E, Civiero, L, Chiarelli, L.R, Galliano, M, Monaco, H.L. | Deposit date: | 2012-11-28 | Release date: | 2013-04-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | BEL {beta}-trefoil: A novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms. Glycobiology, 23, 2013
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