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8JUL
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BU of 8jul by Molmil
Cryo-EM structure of SIDT1 in complex with phosphatidic acid
Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, SID1 transmembrane family member 1, ZINC ION
Authors:Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y.
Deposit date:2023-06-26
Release date:2023-11-15
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Human SIDT1 mediates dsRNA uptake via its phospholipase activity.
Cell Res., 34, 2024
8JUN
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BU of 8jun by Molmil
Cryo-EM structure of SIDT1 E555Q mutant
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SID1 transmembrane family member 1, ZINC ION
Authors:Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y.
Deposit date:2023-06-26
Release date:2023-11-15
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:Human SIDT1 mediates dsRNA uptake via its phospholipase activity.
Cell Res., 34, 2024
7JVN
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BU of 7jvn by Molmil
Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Compound 24
Descriptor: 6-(4-amino-4-methylpiperidin-1-yl)-3-[(2,3-dichlorophenyl)sulfanyl]pyrazin-2-amine, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11
Authors:Fodor, M, Stams, T.
Deposit date:2020-08-21
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.917 Å)
Cite:Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
J.Med.Chem., 63, 2020
8KEE
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BU of 8kee by Molmil
Cyanophage A-1(L) sheath-tube
Descriptor: sheath, tube
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KEA
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BU of 8kea by Molmil
Cyanophage A-1(L) baseplate-initiators
Descriptor: baseplate gp16, central spike, hub, ...
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KEC
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BU of 8kec by Molmil
Cyanophage A-1(L) tail fiber
Descriptor: Long tail fiber, short tail fiber
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KE9
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BU of 8ke9 by Molmil
The CBD domain of cyanophage A-1(L) short tail fiber
Descriptor: Tail fiber protein
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8K66
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BU of 8k66 by Molmil
Cryo-EM structure of Oryza sativa HKT2;1 at 2.5 angstrom
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ...
Authors:Wang, X, Shen, X, Qu, Y, Wang, C, Shen, H.
Deposit date:2023-07-25
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Structural insights into ion selectivity and transport mechanisms of Oryza sativa HKT2;1 and HKT2;2/1 transporters.
Nat.Plants, 10, 2024
8K69
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BU of 8k69 by Molmil
Cryo-EM structure of Oryza sativa HKT2;2/1 at 2.3 angstrom
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ...
Authors:Wang, X, Shen, X, Qu, Y, Wang, C, Shen, H.
Deposit date:2023-07-25
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.33 Å)
Cite:Structural insights into ion selectivity and transport mechanisms of Oryza sativa HKT2;1 and HKT2;2/1 transporters.
Nat.Plants, 10, 2024
8KEG
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BU of 8keg by Molmil
Cyanophage A-1(L) neck/gp5-neck fiber
Descriptor: Neck gp5, neck fiber gp82N
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KEF
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BU of 8kef by Molmil
Cyanophage A-1(L) neck/gp7-terminator
Descriptor: Neck gp7, Terminator gp8
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
7JVM
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BU of 7jvm by Molmil
Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor TNO155
Descriptor: (3S,4S)-8-{6-amino-5-[(2-amino-3-chloropyridin-4-yl)sulfanyl]pyrazin-2-yl}-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11
Authors:Fodor, M, Stams, T.
Deposit date:2020-08-21
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.166 Å)
Cite:Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
J.Med.Chem., 63, 2020
7FDV
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BU of 7fdv by Molmil
Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 1, CHOLESTEROL, ...
Authors:Xu, D, Li, Y.Y, Yang, F.R, Sun, C.R, Pan, J.H, Wang, L, Chen, Z.P, Fang, S.C, Yao, X.B, Hou, W.T, Zhou, C.Z, Chen, Y.
Deposit date:2021-07-18
Release date:2022-06-22
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structure and transport mechanism of the human cholesterol transporter ABCG1.
Cell Rep, 38, 2022
1B9C
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BU of 1b9c by Molmil
Green Fluorescent Protein Mutant F99S, M153T and V163A
Descriptor: PROTEIN (GREEN FLUORESCENT PROTEIN)
Authors:Battistutta, R, Negro, A, Zanotti, G.
Deposit date:1999-02-09
Release date:2000-11-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure and refolding properties of the mutant F99S/M153T/V163A of the green fluorescent protein.
Proteins, 41, 2000
1J4V
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BU of 1j4v by Molmil
CYANOVIRIN-N
Descriptor: CYANOVIRIN-N
Authors:Clore, G.M, Bewley, C.A.
Deposit date:2001-11-21
Release date:2002-03-06
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Using conjoined rigid body/torsion angle simulated annealing to determine the relative orientation of covalently linked protein domains from dipolar couplings.
J.Magn.Reson., 154, 2002
7VDD
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BU of 7vdd by Molmil
Human TOM complex with cross-linking
Descriptor: Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, Mitochondrial import receptor subunit TOM5 homolog, ...
Authors:Liu, D.S, Sui, S.F.
Deposit date:2021-09-06
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VD2
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BU of 7vd2 by Molmil
Human TOM complex without cross-linking
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ...
Authors:Liu, D.S, Sui, S.F.
Deposit date:2021-09-06
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VJT
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BU of 7vjt by Molmil
Crystal Structure of Mtb Pks13-TE in complex with inhibitor coumestan derivative 8
Descriptor: 3,8-bis(oxidanyl)-7-(piperidin-1-ylmethyl)-[1]benzofuro[3,2-c]chromen-6-one, Polyketide synthase Pks13 (Termination polyketide synthase)
Authors:Zhang, W, Wang, S.S, Yu, L.F.
Deposit date:2021-09-28
Release date:2022-09-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment.
J.Med.Chem., 65, 2022
7CFP
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BU of 7cfp by Molmil
Crystal structure of WDR5 in complex with a H3Q5ser peptide
Descriptor: H3Q5ser peptide, SEROTONIN, WD repeat-containing protein 5
Authors:Zhao, J, Zhang, X, Zang, J.
Deposit date:2020-06-27
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021
7CFQ
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BU of 7cfq by Molmil
Crystal structure of WDR5 in complex with H3K4me3Q5ser peptide
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, H3K4me3Q5ser peptide, ...
Authors:Zhao, J, Zhang, X, Zang, J.
Deposit date:2020-06-27
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021
7DFB
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BU of 7dfb by Molmil
Crystal of Arrestin2-V2Rpp-6-7-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DF9
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BU of 7df9 by Molmil
Crystal of Arrestin2-V2Rpp-1-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DFA
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BU of 7dfa by Molmil
Crystal of Arrestin2-V2Rpp-4-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DFC
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BU of 7dfc by Molmil
Crystal of Arrestin2-V2Rpp-3-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DF8
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BU of 7df8 by Molmil
full length hNPC1L1-Apo
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hu, M, Sun, S, Sui, S.
Deposit date:2020-11-06
Release date:2021-08-04
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake.
Sci Adv, 7, 2021

221051

數據於2024-06-12公開中

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