Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5I2N
DownloadVisualize
BU of 5i2n by Molmil
Structure of the human GluN1/GluN2A LBD in complex with N-ethyl-7-{[2-fluoro-3-(trifluoromethyl)phenyl]methyl}-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide (compound 29)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, GLUTAMIC ACID, ...
Authors:Wallweber, H.J.A, Lupardus, P.J.
Deposit date:2016-02-09
Release date:2016-03-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.
J.Med.Chem., 59, 2016
7XHO
DownloadVisualize
BU of 7xho by Molmil
Structure of human inner kinetochore CCAN complex
Descriptor: CENP-W, Centromere protein C, Centromere protein H, ...
Authors:Tian, T, Wang, C.L, Yang, Z.S, Sun, L.F, Zang, J.Y.
Deposit date:2022-04-09
Release date:2022-12-14
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural insights into human CCAN complex assembled onto DNA.
Cell Discov, 8, 2022
7XHN
DownloadVisualize
BU of 7xhn by Molmil
Structure of human inner kinetochore CCAN-DNA complex
Descriptor: CENP-W, Centromere protein C, Centromere protein H, ...
Authors:Sun, L.F, Tian, T, Wang, C.L, Yang, Z.S, Zang, J.Y.
Deposit date:2022-04-09
Release date:2023-01-25
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural insights into human CCAN complex assembled onto DNA.
Cell Discov, 8, 2022
8I8A
DownloadVisualize
BU of 8i8a by Molmil
Cryo-EM structure of the major capsid protein VP39 of Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
Descriptor: Major viral capsid protein
Authors:Jia, X, Zhang, Q.
Deposit date:2023-02-03
Release date:2023-12-13
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
8I8C
DownloadVisualize
BU of 8i8c by Molmil
Plug structure of the Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
Descriptor: Occlusion-derived virus envelope/capsid protein, P40
Authors:Jia, X, Gao, Y, Zhang, Q.
Deposit date:2023-02-03
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (4.93 Å)
Cite:Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
8I8B
DownloadVisualize
BU of 8i8b by Molmil
Outer shell and inner layer structures of Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
Descriptor: 38K, AcOrf-109 peptide, Early 49 Daa protein, ...
Authors:Jia, X, Gao, Y, Zhang, Q.
Deposit date:2023-02-03
Release date:2023-12-13
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.31 Å)
Cite:Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
3KW4
DownloadVisualize
BU of 3kw4 by Molmil
Crystal structure of cytochrome 2B4 in complex with the anti-platelet drug ticlopidine
Descriptor: 2-{[(3alpha,5alpha,7alpha,8alpha,10alpha,12alpha,17alpha)-3,12-bis{2-[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]ethoxy}cholan-7-yl]oxy}ethyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ...
Authors:Gay, S.C, Maekawa, K, Roberts, A.G, Hong, W.-X, Zhang, Q, Stout, C.D, Halpert, J.R.
Deposit date:2009-11-30
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel.
Biochemistry, 49, 2010
6JBH
DownloadVisualize
BU of 6jbh by Molmil
Cryo-EM structure and transport mechanism of a wall teichoic acid ABC transporter
Descriptor: TarG, TarH
Authors:Chen, L, Hou, W.T, Fan, T, Li, Y.H, Liu, B.H, Jiang, Y.L, Sun, L.F, Chen, Y, Zhou, C.Z.
Deposit date:2019-01-25
Release date:2020-03-04
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Cryo-electron Microscopy Structure and Transport Mechanism of a Wall Teichoic Acid ABC Transporter.
Mbio, 11, 2020
6JBJ
DownloadVisualize
BU of 6jbj by Molmil
Cryo-EM structure of human lysosomal cobalamin exporter ABCD4
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 4
Authors:Xu, D, Feng, Z, Hou, W.T, Jiang, Y.L, Wang, L, Sun, L.F, Zhou, C.Z, Chen, Y.
Deposit date:2019-01-25
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of human lysosomal cobalamin exporter ABCD4.
Cell Res., 29, 2019
3ME6
DownloadVisualize
BU of 3me6 by Molmil
Crystal structure of cytochrome 2B4 in complex with the anti-platelet drug clopidogrel
Descriptor: Clopidogrel, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
Authors:Gay, S.C, Roberts, A.G, Maekawa, K, Talakad, J.C, Hong, W.X, Zhang, Q, Stout, C.D, Halpert, J.R.
Deposit date:2010-03-31
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel.
Biochemistry, 49, 2010
1QNE
DownloadVisualize
BU of 1qne by Molmil
Crystal structure of the Adenovirus major late promoter TATA box bound to wild-type TBP (Arabidopsis thaliana TBP isoform 2).
Descriptor: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TRANSCRIPTION INITIATION FACTOR TFIID-1
Authors:Kim, J.L, Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
4O8S
DownloadVisualize
BU of 4o8s by Molmil
Crystal structure of JHP933 from Helicobacter pylori
Descriptor: Putative
Authors:Zhao, Y.H, Su, Y.T, Sun, L.F, Wu, Y.
Deposit date:2013-12-30
Release date:2014-09-10
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure Confirmation of JHP933 as a Nucleotidyltransferase Superfamily Protein from Helicobacter pylori Strain J99
Plos One, 9, 2014
3MVR
DownloadVisualize
BU of 3mvr by Molmil
Crystal Structure of cytochrome P450 2B4-H226Y in a closed conformation
Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
Authors:Shah, M.B, Stout, C.D, Halpert, J.R.
Deposit date:2010-05-04
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography.
J.Biol.Chem., 285, 2010
3TK3
DownloadVisualize
BU of 3tk3 by Molmil
Cytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazole
Descriptor: 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
Authors:Gay, S.C, Jang, H.H, Wilderman, P.R, Zhang, Q, Stout, C.D, Halpert, J.R.
Deposit date:2011-08-25
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8001 Å)
Cite:Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme.
Febs J., 279, 2012
3Q0T
DownloadVisualize
BU of 3q0t by Molmil
Crystal structure of human dpp-iv in complex withsa-(+)- methyl2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl- 7-oxo-5h-pyrrolo[3,4-b]pyridin-6(7h)-yl)acetate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ...
Authors:Klei, H.E.
Deposit date:2010-12-16
Release date:2012-02-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Discovery of 7-oxo-pyrrolopyridines as potent and selective inhibitors of dpp4
To be Published
8XEW
DownloadVisualize
BU of 8xew by Molmil
Cryo-EM structure of defence-associatedsirtuin 2 (DSR2) H171A protein
Descriptor: DSR2 H171A
Authors:Li, Y, Zhang, H, Zheng, Q, Wu, Y, Li, S.
Deposit date:2023-12-13
Release date:2024-10-23
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Structural insights into activation mechanisms on NADase of the bacterial DSR2 anti-phage defense system.
Sci Adv, 10, 2024
3UAS
DownloadVisualize
BU of 3uas by Molmil
Cytochrome P450 2B4 covalently bound to the mechanism-based inactivator 9-ethynylphenanthrene
Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Gay, S.C, Zhang, H, Shah, M.B, Stout, C.D, Halpert, J.R, Hollenberg, P.F.
Deposit date:2011-10-21
Release date:2013-01-09
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.939 Å)
Cite:Potent Mechanism-Based Inactivation of Cytochrome P450 2B4 by 9-Ethynylphenanthrene: Implications for Allosteric Modulation of Cytochrome P450 Catalysis.
Biochemistry, 52, 2013
6L30
DownloadVisualize
BU of 6l30 by Molmil
Crystal structure of the epithelial cell transforming 2 (ECT2)
Descriptor: Protein ECT2
Authors:Chen, Z.C, Chen, M.R, Pan, H, Sun, L.F, Shi, P.
Deposit date:2019-10-07
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and regulation of human epithelial cell transforming 2 protein.
Proc.Natl.Acad.Sci.USA, 117, 2020
6L6S
DownloadVisualize
BU of 6l6s by Molmil
The structure of the UdgX mutant H109E crosslinked to single-stranded DNA
Descriptor: DNA (5'-D(P*TP*GP*(ORP)P*AP*GP*GP*CP*AP*TP*GP*C)-3'), IRON/SULFUR CLUSTER, Phage SPO1 DNA polymerase-related protein
Authors:Xie, W, Tu, J, Zeng, H.
Deposit date:2019-10-29
Release date:2020-11-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.06425953 Å)
Cite:Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
6L5B
DownloadVisualize
BU of 6l5b by Molmil
The structure of the UdgX mutant H109E at a post-excision state
Descriptor: IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein
Authors:Xie, W, Tu, J, Zeng, H.
Deposit date:2019-10-22
Release date:2020-10-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.00004983 Å)
Cite:Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
5Y3X
DownloadVisualize
BU of 5y3x by Molmil
Crystal structure of endo-1,4-beta-xylanase from Caldicellulosiruptor owensensis
Descriptor: Beta-xylanase
Authors:Liu, X, Sun, L.C, Zhang, Y.B, Liu, T.F, Xin, F.J.
Deposit date:2017-07-31
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into the Thermophilic Adaption Mechanism of Endo-1,4-beta-Xylanase from Caldicellulosiruptor owensensis.
J. Agric. Food Chem., 66, 2018
6L5A
DownloadVisualize
BU of 6l5a by Molmil
The structure of the UdgX mutant H109E at a pre-excision state
Descriptor: GLYCEROL, IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein
Authors:Xie, W, Tu, J, Zeng, H.
Deposit date:2019-10-22
Release date:2020-10-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.80007327 Å)
Cite:Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
7MFH
DownloadVisualize
BU of 7mfh by Molmil
Crystal structure of BIO-32546 bound mouse Autotaxin
Descriptor: (1R,3S,5S)-8-{(1S)-1-[8-(trifluoromethyl)-7-{[(1s,4R)-4-(trifluoromethyl)cyclohexyl]oxy}naphthalen-2-yl]ethyl}-8-azabicyclo[3.2.1]octane-3-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chodaparambil, J.V.
Deposit date:2021-04-09
Release date:2022-04-13
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of Potent Selective Nonzinc Binding Autotaxin Inhibitor BIO-32546.
Acs Med.Chem.Lett., 12, 2021
6UH7
DownloadVisualize
BU of 6uh7 by Molmil
EV-A71 strain 11316 complexed with MADAL compound 30
Descriptor: SPHINGOSINE, VP1, VP2, ...
Authors:Lee, H, Hafenstein, S.
Deposit date:2019-09-26
Release date:2019-12-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Scaffold Simplification Strategy Leads to a Novel Generation of Dual Human Immunodeficiency Virus and Enterovirus-A71 Entry Inhibitors.
J.Med.Chem., 63, 2020
6UH6
DownloadVisualize
BU of 6uh6 by Molmil
EV-A71 strain 11316 complexed with MADAL compound 22
Descriptor: SPHINGOSINE, VP1, VP2, ...
Authors:Lee, H, Hafenstein, S.
Deposit date:2019-09-26
Release date:2019-12-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Scaffold Simplification Strategy Leads to a Novel Generation of Dual Human Immunodeficiency Virus and Enterovirus-A71 Entry Inhibitors.
J.Med.Chem., 63, 2020

238582

數據於2025-07-09公開中

PDB statisticsPDBj update infoContact PDBjnumon