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7VUY
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BU of 7vuy by Molmil
Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12. state1
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Li, Y, Yang, F.
Deposit date:2021-11-04
Release date:2021-12-01
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
7VV3
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BU of 7vv3 by Molmil
Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with linear cortistatin-14
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Li, Y, Yang, F.
Deposit date:2021-11-04
Release date:2021-12-01
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
7DZ2
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BU of 7dz2 by Molmil
Crystal structures of D-allulose 3-epimerase from Sinorhizobium fredii
Descriptor: D-tagatose 3-epimerase, MAGNESIUM ION, SULFATE ION
Authors:Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
Deposit date:2021-01-23
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
7DZ3
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BU of 7dz3 by Molmil
Crystal structures of D-allulose 3-epimerase with D-fructose from Sinorhizobium fredii
Descriptor: D-fructose, D-tagatose 3-epimerase, MAGNESIUM ION
Authors:Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
Deposit date:2021-01-23
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
7DZ4
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BU of 7dz4 by Molmil
Crystal structures of D-allulose 3-epimerase with D-tagatose from Sinorhizobium fredii
Descriptor: D-tagatose, D-tagatose 3-epimerase, MAGNESIUM ION
Authors:Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
Deposit date:2021-01-23
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
7DZ6
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BU of 7dz6 by Molmil
Crystal structures of D-allulose 3-epimerase with D-allulose from Sinorhizobium fredii
Descriptor: D-psicose, D-tagatose 3-epimerase, MAGNESIUM ION
Authors:Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
Deposit date:2021-01-23
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
8W4A
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BU of 8w4a by Molmil
membrane proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYL COENZYME *A, ...
Authors:Yu, J, Ge, J.P, Xu, R.S.
Deposit date:2023-08-23
Release date:2024-10-23
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structure and mechanism of lysosome transmembrane acetylation by HGSNAT.
Nat.Struct.Mol.Biol., 31, 2024
6K6U
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BU of 6k6u by Molmil
Crystal structure of the human YTHDC2 YTH domain
Descriptor: 3'-5' RNA helicase YTHDC2
Authors:Ma, C, Liao, S, Xu, C.
Deposit date:2019-06-04
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human YTHDC2 YTH domain.
Biochem.Biophys.Res.Commun., 518, 2019
7EWF
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BU of 7ewf by Molmil
Selenomethionine-substituted structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
Descriptor: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
Authors:Kuang, Z, Niu, L.
Deposit date:2021-05-25
Release date:2022-09-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022
7EWM
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BU of 7ewm by Molmil
Native crystal structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
Descriptor: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
Authors:Kuang, Z, Niu, L.
Deposit date:2021-05-25
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022
6LBG
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BU of 6lbg by Molmil
Structure of OR51B2 bound FEM1C
Descriptor: Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-14
Release date:2020-10-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LE6
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BU of 6le6 by Molmil
Structure of LNLPTQGRAR bound FEM1C
Descriptor: Protein fem-1 homolog C,10-mer peptide, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-24
Release date:2020-10-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LBF
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BU of 6lbf by Molmil
Crystal structure of FEM1B
Descriptor: Protein fem-1 homolog B, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-14
Release date:2020-10-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.252 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LDP
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BU of 6ldp by Molmil
Structure of CDK5R1-bound FEM1C
Descriptor: Protein fem-1 homolog C,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-22
Release date:2020-10-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
7D8D
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BU of 7d8d by Molmil
The crystal structure of ScNTM1 in complex with SAH and Rps25a hexapeptide
Descriptor: Alpha N-terminal protein methyltransferase 1, Rps25A-peptide, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Zhang, H.Y, Yue, J.
Deposit date:2020-10-08
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structural Basis for Peptide Binding of Alpha-N Terminal Methyltransferase from Saccharomyces cerevisiae
Crystallography Reports, 66, 2021
7EXC
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BU of 7exc by Molmil
Crystal structure of T2R-TTL-1129A2 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Yang, J.H, Yan, W.
Deposit date:2021-05-26
Release date:2022-06-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure-Based Design and Synthesis of N-Substituted 3-Amino-beta-Carboline Derivatives as Potent alpha beta-Tubulin Degradation Agents
J.Med.Chem., 65, 2022
8IG4
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BU of 8ig4 by Molmil
Crystal structure of SARS-Cov-2 main protease in complex with GC376
Descriptor: Non-structural protein 11, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
Authors:Zhou, X.L, Zhang, J, Li, J.
Deposit date:2023-02-20
Release date:2024-03-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG5
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BU of 8ig5 by Molmil
Crystal structure of SARS main protease in complex with GC376
Descriptor: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
Authors:Lin, C, Zhang, J, Li, J.
Deposit date:2023-02-20
Release date:2024-03-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG6
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BU of 8ig6 by Molmil
Crystal structure of MERS main protease in complex with GC376
Descriptor: N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide, ORF1a
Authors:Lin, C, Zhang, J, Li, J.
Deposit date:2023-02-20
Release date:2024-03-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG8
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BU of 8ig8 by Molmil
Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with GC376
Descriptor: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
Authors:Zeng, X.Y, Zhang, J, Li, J.
Deposit date:2023-02-20
Release date:2024-03-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG7
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BU of 8ig7 by Molmil
Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with GC376
Descriptor: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
Authors:Zeng, P, Zhang, J, Li, J.
Deposit date:2023-02-20
Release date:2024-03-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG9
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BU of 8ig9 by Molmil
Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with GC376
Descriptor: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
Authors:Zou, X.F, Zhang, J, Li, J.
Deposit date:2023-02-20
Release date:2024-03-06
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IGA
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BU of 8iga by Molmil
Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with GC376
Descriptor: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
Authors:Wang, J, Zhang, J, Li, J.
Deposit date:2023-02-20
Release date:2024-03-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IGB
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BU of 8igb by Molmil
Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with GC376
Descriptor: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
Authors:Li, W.W, Zhang, J, Li, J.
Deposit date:2023-02-20
Release date:2024-03-06
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8J1X
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BU of 8j1x by Molmil
A near-infrared fluorescent protein of de novo backbone design
Descriptor: near-infrared fluorescent protein
Authors:Hu, X, Xu, Y.
Deposit date:2023-04-13
Release date:2023-10-04
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Using Protein Design and Directed Evolution to Monomerize a Bright Near-Infrared Fluorescent Protein.
Acs Synth Biol, 13, 2024

226707

數據於2024-10-30公開中

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