7F64
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![BU of 7f64 by Molmil](/molmil-images/mine/7f64) | eIF2B-SFSV NSs | Descriptor: | Non-structural protein NS-S, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | Authors: | Kashiwagi, K, Ito, T. | Deposit date: | 2021-06-24 | Release date: | 2021-12-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | eIF2B-capturing viral protein NSs suppresses the integrated stress response. Nat Commun, 12, 2021
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7WYR
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![BU of 7wyr by Molmil](/molmil-images/mine/7wyr) | Crystal structure of Cypovirus Polyhedra mutant fused with CLN025 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Polyhedrin fused with CLN025 | Authors: | Kojima, M, Abe, S, Hirata, K, Yamashita, K, Ueno, T. | Deposit date: | 2022-02-16 | Release date: | 2023-02-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Engineering of an in-cell protein crystal for fastening a metastable conformation of a target miniprotein. Biomater Sci, 11, 2023
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3PFK
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![BU of 3pfk by Molmil](/molmil-images/mine/3pfk) | |
8HMM
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![BU of 8hmm by Molmil](/molmil-images/mine/8hmm) | Crystal structure of AoRhaA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bac_rhamnosid6H domain-containing protein | Authors: | Makabe, K, Koseki, T. | Deposit date: | 2022-12-05 | Release date: | 2023-12-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Aspergillus oryzae alpha-l-rhamnosidase: Crystal structure and insight into the substrate specificity. Proteins, 92, 2024
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8II1
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![BU of 8ii1 by Molmil](/molmil-images/mine/8ii1) | Crystal structure of V30M-TTR in complex with BID | Descriptor: | Benziodarone, Transthyretin | Authors: | Yokoyama, T. | Deposit date: | 2023-02-24 | Release date: | 2023-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.907 Å) | Cite: | Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90, 2023
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8II3
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![BU of 8ii3 by Molmil](/molmil-images/mine/8ii3) | Crystal structure of V30M-TTR in complex with 6-hydroxy BID | Descriptor: | Transthyretin, [3,5-bis(iodanyl)-4-oxidanyl-phenyl]-(2-ethyl-6-oxidanyl-1-benzofuran-3-yl)methanone | Authors: | Yokoyama, T. | Deposit date: | 2023-02-24 | Release date: | 2023-06-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.399 Å) | Cite: | Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90, 2023
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8II4
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![BU of 8ii4 by Molmil](/molmil-images/mine/8ii4) | Crystal structure of V30M-TTR in complex with 6-hydroxy BBM | Descriptor: | Transthyretin, [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-6-oxidanyl-1-benzofuran-3-yl)methanone | Authors: | Yokoyama, T. | Deposit date: | 2023-02-24 | Release date: | 2023-06-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90, 2023
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8II2
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![BU of 8ii2 by Molmil](/molmil-images/mine/8ii2) | Crystal structure of V30M-TTR in complex with BBM | Descriptor: | CALCIUM ION, Transthyretin, [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone | Authors: | Yokoyama, T. | Deposit date: | 2023-02-24 | Release date: | 2023-06-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90, 2023
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2Z4D
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2PD2
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![BU of 2pd2 by Molmil](/molmil-images/mine/2pd2) | Crystal structure of (ST0148) conserved hypothetical from Sulfolobus Tokodaii Strain7 | Descriptor: | Hypothetical protein ST0148 | Authors: | Jeyakanthan, J, Kanaujia, S.P, Rafi, Z.A, Sekar, K, Agari, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-31 | Release date: | 2007-10-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Crystal structure of (ST0148) conserved hypothetical from Sulfolobus Tokodaii Strain7 To be Published
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5XQV
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![BU of 5xqv by Molmil](/molmil-images/mine/5xqv) | Crystal structure of Notched-fin eelpout type III antifreeze protein A20L mutant (NFE6, AFP), P21 form | Descriptor: | Ice-structuring protein | Authors: | Adachi, M, Shimizu, R, Shibazaki, C, Kondo, H, Tsuda, S. | Deposit date: | 2017-06-07 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Polypentagonal ice-like water networks emerge solely in an activity-improved variant of ice-binding protein Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5XR0
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![BU of 5xr0 by Molmil](/molmil-images/mine/5xr0) | Crystal structure of Notched-fin eelpout type III antifreeze protein A20T mutant (NFE6, AFP), P21 form | Descriptor: | Ice-structuring protein | Authors: | Adachi, M, Shimizu, R, Shibazaki, C, Kondo, H, Tsuda, S. | Deposit date: | 2017-06-07 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Polypentagonal ice-like water networks emerge solely in an activity-improved variant of ice-binding protein Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3WDR
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![BU of 3wdr by Molmil](/molmil-images/mine/3wdr) | Crystal structure of beta-mannanase from a symbiotic protist of the termite Reticulitermes speratus complexed with gluco-manno-oligosaccharide | Descriptor: | BICARBONATE ION, Beta-mannanase, MAGNESIUM ION, ... | Authors: | Tsukagoshi, H, Ishida, T, Touhara, K.K, Igarashi, K, Samejima, M, Fushinobu, S, Kitamoto, K, Arioka, M. | Deposit date: | 2013-06-20 | Release date: | 2014-03-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and Biochemical Analyses of Glycoside Hydrolase Family 26 beta-Mannanase from a Symbiotic Protist of the Termite Reticulitermes speratus J.Biol.Chem., 289, 2014
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6JMF
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![BU of 6jmf by Molmil](/molmil-images/mine/6jmf) | |
3WDQ
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![BU of 3wdq by Molmil](/molmil-images/mine/3wdq) | Crystal structure of beta-mannanase from a symbiotic protist of the termite Reticulitermes speratus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-mannanase, MAGNESIUM ION, ... | Authors: | Tsukagoshi, H, Ishida, T, Touhara, K.K, Igarashi, K, Samejima, M, Fushinobu, S, Kitamoto, K, Arioka, M. | Deposit date: | 2013-06-20 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural and Biochemical Analyses of Glycoside Hydrolase Family 26 beta-Mannanase from a Symbiotic Protist of the Termite Reticulitermes speratus J.Biol.Chem., 289, 2014
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7KZE
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![BU of 7kze by Molmil](/molmil-images/mine/7kze) | Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity | Descriptor: | 1-benzyl-4-methoxybenzene, Leukotriene A-4 hydrolase, TRIETHYLENE GLYCOL, ... | Authors: | Lee, K.H, Shim, Y, Paige, M, Noble, S.M. | Deposit date: | 2020-12-10 | Release date: | 2022-06-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation. Sci Rep, 12, 2022
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1L3H
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![BU of 1l3h by Molmil](/molmil-images/mine/1l3h) | NMR structure of P41icf, a potent inhibitor of human cathepsin L | Descriptor: | MHC CLASS II-ASSOCIATED P41 INVARIANT CHAIN FRAGMENT (P41icf) | Authors: | Chiva, C, Barthe, P, Codina, A, Giralt, E. | Deposit date: | 2002-02-27 | Release date: | 2003-03-04 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Synthesis and NMR structure of P41ICF, a potent inhibitor of human cathepsin L J.Am.Chem.Soc., 125, 2003
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5XQU
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![BU of 5xqu by Molmil](/molmil-images/mine/5xqu) | Crystal structure of Notched-fin eelpout type III antifreeze protein A20I mutant (NFE6, AFP), P212121 form | Descriptor: | Ice-structuring protein | Authors: | Adachi, M, Shimizu, R, Shibazaki, C, Kondo, H, Tsuda, S. | Deposit date: | 2017-06-07 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Polypentagonal ice-like water networks emerge solely in an activity-improved variant of ice-binding protein Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5XQP
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![BU of 5xqp by Molmil](/molmil-images/mine/5xqp) | Crystal structure of Notched-fin eelpout type III antifreeze protein (NFE6, AFP), P212121 form | Descriptor: | Ice-structuring protein, SULFATE ION | Authors: | Adachi, M, Shimizu, R, Shibazaki, C, Kondo, H, Tsuda, S. | Deposit date: | 2017-06-07 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Polypentagonal ice-like water networks emerge solely in an activity-improved variant of ice-binding protein Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5XQR
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![BU of 5xqr by Molmil](/molmil-images/mine/5xqr) | Crystal structure of Notched-fin eelpout type III antifreeze protein A20V mutant (NFE6, AFP), C2221 form | Descriptor: | ACETATE ION, Ice-structuring protein | Authors: | Adachi, M, Shimizu, R, Shibazaki, C, Kondo, H, Tsuda, S. | Deposit date: | 2017-06-07 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Polypentagonal ice-like water networks emerge solely in an activity-improved variant of ice-binding protein Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7DVE
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![BU of 7dve by Molmil](/molmil-images/mine/7dve) | Crystal structure of FAD-dependent C-glycoside oxidase | Descriptor: | 6'''-hydroxyparomomycin C oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | Authors: | Senda, M, Watanabe, S, Kumano, T, Kobayashi, M, Senda, T. | Deposit date: | 2021-01-13 | Release date: | 2021-09-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | FAD-dependent C -glycoside-metabolizing enzymes in microorganisms: Screening, characterization, and crystal structure analysis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7DVS
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![BU of 7dvs by Molmil](/molmil-images/mine/7dvs) | Crystal structure of Apo (heme-free) PefR | Descriptor: | MarR family transcriptional regulator | Authors: | Muraki, N, Aono, S. | Deposit date: | 2021-01-15 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival. Commun Biol, 4, 2021
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7E6P
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![BU of 7e6p by Molmil](/molmil-images/mine/7e6p) | Fab-amyloid beta fragment complex | Descriptor: | 1,2-ETHANEDIOL, Amyloid beta fragment with an intramolecular disulfide bond at positions 17 and 28, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kita, A, Irie, K, Irie, Y, Miki, K. | Deposit date: | 2021-02-23 | Release date: | 2022-01-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Characterization of a Conformation-Restricted Amyloid beta Peptide and Immunoreactivity of Its Antibody in Human AD brain. Acs Chem Neurosci, 12, 2021
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6J8Y
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![BU of 6j8y by Molmil](/molmil-images/mine/6j8y) | Crystal structure of the human RAD9-HUS1-RAD1-RHINO complex | Descriptor: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ... | Authors: | Hara, K, Iida, N, Sakurai, H, Hashimoto, H. | Deposit date: | 2019-01-21 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp. J.Biol.Chem., 295, 2020
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5YSD
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![BU of 5ysd by Molmil](/molmil-images/mine/5ysd) | Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophorotriose | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Lin1841 protein, MAGNESIUM ION, ... | Authors: | Abe, K, Nakajima, M, Taguchi, H, Arakawa, T, Fushinobu, S. | Deposit date: | 2017-11-14 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and thermodynamic insights into beta-1,2-glucooligosaccharide capture by a solute-binding protein inListeria innocua. J. Biol. Chem., 293, 2018
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