1L3H

NMR structure of P41icf, a potent inhibitor of human cathepsin L

Summary for 1L3H

• Entry DOI: 10.2210/pdb1l3h/pdb
• Related: 1ICF
• NMR Information: BMRB: 5583
• Descriptor: MHC CLASS II-ASSOCIATED P41 INVARIANT CHAIN FRAGMENT (P41icf) (1 entity in total)
• Functional Keywords: alpha helix, beta sheet, disulfide bonds, immune system
• Cellular location: Cell membrane; Single-pass type II membrane protein (Potential): P04233
• Total number of polymer chains: 1
• Total formula weight: 7261.07

Authors

Chiva, C.,Barthe, P.,Codina, A.,Giralt, E. (deposition date: 2002-02-27, release date: 2003-03-04, Last modification date: 2022-02-23)

• Primary citation: Chiva, C.,Barthe, P.,Codina, A.,Gairi, M.,Molina, F.,Granier, C.,Pugniere, M.,Inui, T.,Nishio, H.,Nishiuchi, Y.,Kimura, T.,Sakakibara, S.,Albericio, F.,Giralt, E.; Synthesis and NMR structure of P41ICF, a potent inhibitor of human cathepsin L; J.Am.Chem.Soc., 125:1508-1517, 2003; PubMed: 12568610; DOI: 10.1021/ja0207908

Experimental method

SOLUTION NMR