3J2W
| Electron cryo-microscopy of Chikungunya virus | Descriptor: | Capsid protein, Glycoprotein E1, Glycoprotein E2 | Authors: | Sun, S, Xiang, Y, Rossmann, M.G. | Deposit date: | 2013-01-28 | Release date: | 2013-04-24 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. Elife, 2, 2013
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3MUU
| Crystal structure of the Sindbis virus E2-E1 heterodimer at low pH | Descriptor: | Structural polyprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, L, Jose, J, Xiang, Y, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2010-05-03 | Release date: | 2010-11-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Structural changes of envelope proteins during alphavirus fusion. Nature, 468, 2010
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3MUW
| Pseudo-atomic structure of the E2-E1 protein shell in Sindbis virus | Descriptor: | Structural polyprotein | Authors: | Li, L, Jose, J, Xiang, Y, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2010-05-03 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structural changes of envelope proteins during alphavirus fusion. Nature, 468, 2010
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3J2Z
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6A7F
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7XEY
| EDS1-PAD4 complexed with pRib-ADP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-O-phosphono-beta-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Huang, S, Jia, A, Xiao, Y. | Deposit date: | 2022-03-31 | Release date: | 2022-07-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity. Science, 377, 2022
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8HFF
| Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom. | Descriptor: | L-NOREPINEPHRINE, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-10 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter To Be Published
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8HFL
| Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant bupropion in an inward-open state at resolution of 3.0 angstrom. | Descriptor: | Bupropion, CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-11 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter To Be Published
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8HFI
| Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant desipramine in an inward-open state at resolution of 2.5 angstrom. | Descriptor: | 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-10 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter To Be Published
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8HFG
| Cryo-EM structure of human norepinephrine transporter NET in the presence of dopamine in an inward-open state at resolution of 3.0 angstrom. | Descriptor: | CHLORIDE ION, L-DOPAMINE, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-10 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter To Be Published
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8HFE
| Cryo-EM structure of human norepinephrine transporter NET in an inward-open state at resolution of 2.5 angstrom | Descriptor: | CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-10 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter To Be Published
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6JEP
| Structure of a neutralizing antibody bound to the Zika envelope protein domain III | Descriptor: | Genome polyprotein, heavy chain of Fab ZK2B10, light chain of Fab ZK2B10 | Authors: | Wang, L, Wang, R.K, Wang, L, Ben, H.J, Yu, L, Gao, F, Shi, X.L, Yin, C.B, Zhang, F.C, Xiang, Y, Zhang, L.Q. | Deposit date: | 2019-02-07 | Release date: | 2019-05-15 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (2.316 Å) | Cite: | Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody. Cell Rep, 26, 2019
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6KU9
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6JFH
| The asymmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex | Descriptor: | FabZK2B10 heavy chain, FabZK2B10 light chain, ZIKV structural E protein, ... | Authors: | Wang, L, Wang, R.K, Wang, L, Ben, H.J, Yu, L, Gao, F, Shi, X.L, Yin, C.B, Zhang, F.C, Xiang, Y, Zhang, L.Q. | Deposit date: | 2019-02-08 | Release date: | 2019-04-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody. Cell Rep, 26, 2019
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7EJV
| The co-crystal structure of DYRK2 with YK-2-69 | Descriptor: | Dual specificity tyrosine-phosphorylation-regulated kinase 2, [6-[[4-[2-(dimethylamino)-1,3-benzothiazol-6-yl]-5-fluoranyl-pyrimidin-2-yl]amino]pyridin-3-yl]-(4-ethylpiperazin-1-yl)methanone | Authors: | Li, Z, Xiao, Y, Yuan, K, Kuang, W, Xiuquan, Y, Yang, P. | Deposit date: | 2021-04-02 | Release date: | 2022-04-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer. Nat Commun, 13, 2022
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7XY1
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7XYC
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7Y3T
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7Y22
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7Y23
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7Y1C
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7Y5S
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7WIF
| The THF-II riboswitch bound to H4B | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, RNA (50-MER) | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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7WIE
| The THF-II riboswitch bound to 7DG | Descriptor: | 7-DEAZAGUANINE, RNA (50-MER) | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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7WIA
| The apo-form of THF-II C22G riboswitch | Descriptor: | RNA (50-MER) | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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