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8G4H
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BU of 8g4h by Molmil
KRAS G13C complex with GDP imaged on a cryo-EM imaging scaffold
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-09
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4E
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BU of 8g4e by Molmil
Green Fluorescence Protein imaged on a cryo-EM imaging scaffold
Descriptor: RCG-10 - Cryo-EM imaging scaffold subunit B fused to DARPin, Superfolder Green Fluorescent Protein
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-09
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G42
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BU of 8g42 by Molmil
KRAS G12C complex with GDP imaged on a cryo-EM imaging scaffold
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-08
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4F
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BU of 8g4f by Molmil
KRAS G12V complex with GDP imaged on a cryo-EM imaging scaffold
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-09
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
6ANV
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BU of 6anv by Molmil
Crystal structure of anti-CRISPR protein AcrF1
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Yang, H, Patel, D.J.
Deposit date:2017-08-14
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.265 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6ANW
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BU of 6anw by Molmil
Crystal structure of anti-CRISPR protein AcrF10
Descriptor: anti-CRISPR protein AcrF10
Authors:Yang, H, Patel, D.J.
Deposit date:2017-08-14
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
4KHX
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BU of 4khx by Molmil
Crystal structure of gp41 helix complexed with antibody 8062
Descriptor: 8062 heavy chain, 8062 light chain, gp41 helix
Authors:Li, M, Gustchina, A, Wlodawer, A.
Deposit date:2013-05-01
Release date:2014-03-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.921 Å)
Cite:Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Plos One, 8, 2013
4YE6
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BU of 4ye6 by Molmil
The crystal structure of the intact human GlnRS
Descriptor: Glutamine--tRNA ligase
Authors:Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE9
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BU of 4ye9 by Molmil
The crystal structure of the G45V mutant of human GlnRS
Descriptor: Glutamine--tRNA ligase
Authors:Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE8
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BU of 4ye8 by Molmil
The crystal structure of the Y57H mutant of human GlnRS
Descriptor: Glutamine--tRNA ligase
Authors:Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4KHT
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BU of 4kht by Molmil
Triple helix bundle of GP41 complexed with fab 8066
Descriptor: 8066 heavy chain, 8066 light chain, Gp41 helix
Authors:Li, M, Gustchina, A, Wlodawer, A.
Deposit date:2013-05-01
Release date:2014-03-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.817 Å)
Cite:Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Plos One, 8, 2013
4ZDP
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BU of 4zdp by Molmil
The crystal structure of Y334C mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ...
Authors:French, R.L, Simonovic, M.
Deposit date:2015-04-17
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
3J70
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BU of 3j70 by Molmil
Model of gp120, including variable regions, in complex with CD4 and 17b
Descriptor: Envelope glycoprotein gp120, T-cell surface glycoprotein CD4, envelope glycoprotein gp41, ...
Authors:Rasheed, M, Bettadapura, R, Bajaj, C.
Deposit date:2014-04-22
Release date:2015-08-26
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.
Structure, 23, 2015
4WXI
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BU of 4wxi by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR trans-N-{(1S)-1-[4-(3-amino-2H-indazol-6-yl)pyridin-2-yl]-2-phenylethyl}-4-(aminomethyl)cyclohexanecarboxamide
Descriptor: 1,2-ETHANEDIOL, COAGULATION FACTOR XI, LIGHT CHAIN, ...
Authors:Wei, A.
Deposit date:2014-11-13
Release date:2015-01-28
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Pyridine and pyridinone-based factor XIa inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015

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數據於2024-07-31公開中

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