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6SCT
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BU of 6sct by Molmil
Cryo-EM structure of the consensus triskelion hub of the clathrin coat complex
Descriptor: Clathrin heavy chain, Clathrin light chain
Authors:Morris, K.L, Cameron, A.D, Sessions, R, Smith, C.J.
Deposit date:2019-07-25
Release date:2019-10-02
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.69 Å)
Cite:Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly.
Nat.Struct.Mol.Biol., 26, 2019
8EUF
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BU of 8euf by Molmil
Class2 of the INO80-Nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F.
Deposit date:2022-10-18
Release date:2023-07-12
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8EUJ
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BU of 8euj by Molmil
Class2 of the INO80-Nucleosome complex
Descriptor: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F.
Deposit date:2022-10-18
Release date:2023-07-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8ETT
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BU of 8ett by Molmil
Class1 of the INO80-Hexasome complex
Descriptor: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
Deposit date:2022-10-17
Release date:2023-07-12
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (6.68 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8ETV
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BU of 8etv by Molmil
Class2 of the INO80-Hexasome complex
Descriptor: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
Deposit date:2022-10-17
Release date:2023-07-12
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8EU2
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BU of 8eu2 by Molmil
Class3 of the INO80-Hexasome complex
Descriptor: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
Deposit date:2022-10-18
Release date:2023-07-12
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8EU9
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BU of 8eu9 by Molmil
Class1 of the INO80-Nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
Deposit date:2022-10-18
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8EUE
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BU of 8eue by Molmil
Class1 of the INO80-Nucleosome complex
Descriptor: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F.
Deposit date:2022-10-18
Release date:2023-07-12
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8ETU
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BU of 8etu by Molmil
Class2 of the INO80-Hexasome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
Deposit date:2022-10-17
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8ETW
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BU of 8etw by Molmil
Class3 of INO80-Hexasome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F.
Deposit date:2022-10-17
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
8ETS
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BU of 8ets by Molmil
Class1 of the INO80-Hexasome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
Deposit date:2022-10-17
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
4DUS
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BU of 4dus by Molmil
Structure of Bace-1 (Beta-Secretase) in complex with N-((2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino)butan-2-yl)acetamide
Descriptor: Beta-secretase 1, GLYCEROL, IODIDE ION, ...
Authors:Sickmier, E.A.
Deposit date:2012-02-22
Release date:2012-10-10
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of beta-Secretase.
ACS Med Chem Lett, 3, 2012
8G17
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BU of 8g17 by Molmil
CryoEM structure of wild-type GAPDH
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase
Authors:Choi, W.Y, Wu, H, Cheng, Y.F.
Deposit date:2023-02-01
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (1.98 Å)
Cite:Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G15
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BU of 8g15 by Molmil
CryoEM structure of nuclear GAPDH under 24h Oxidative Stress
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase
Authors:Choi, W.Y, Wu, H, Cheng, Y.F.
Deposit date:2023-02-01
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.07 Å)
Cite:Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G13
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BU of 8g13 by Molmil
CryoEM structure of cytosolic GAPDH under 8h Oxidative Stress
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase
Authors:Choi, W.Y, Wu, H, Cheng, Y.F.
Deposit date:2023-02-01
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G12
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BU of 8g12 by Molmil
CryoEM structure of nuclear GAPDH under 8h Oxidative Stress
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase
Authors:Choi, W.Y, Wu, H, Cheng, Y.F.
Deposit date:2023-02-01
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.17 Å)
Cite:Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G14
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BU of 8g14 by Molmil
CryoEM structure of cytosolic GAPDH under 8h Oxidative Stress, class2
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase
Authors:Choi, W.Y, Wu, H, Cheng, Y.F.
Deposit date:2023-02-01
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G16
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BU of 8g16 by Molmil
CryoEM structure of cytoplasmic GAPDH under 24h Oxidative Stress
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase
Authors:Choi, W.Y, Wu, H, Cheng, Y.F.
Deposit date:2023-02-01
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.07 Å)
Cite:Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
4NIE
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BU of 4nie by Molmil
Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with small molecule ligand
Descriptor: 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, N-(4-{[benzyl(propyl)amino]methyl}phenyl)-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, ...
Authors:Ma, Y.L, Yang, L.Q.
Deposit date:2013-11-06
Release date:2013-12-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Discovery of Tertiary Amine and Indole Derivatives as Potent ROR gamma t Inverse Agonists.
Acs Med.Chem.Lett., 5, 2014
7KDT
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BU of 7kdt by Molmil
Human Tom70 in complex with SARS CoV2 Orf9b
Descriptor: Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 370, 2020
8CVT
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BU of 8cvt by Molmil
Human 19S-20S proteasome, state SD2
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Zhao, J.
Deposit date:2022-05-18
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
8CVR
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BU of 8cvr by Molmil
Human 20S proteasome with MG-132
Descriptor: N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ...
Authors:Zhao, J.
Deposit date:2022-05-18
Release date:2022-11-02
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
8CVS
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BU of 8cvs by Molmil
Human PA200-20S proteasome with MG-132
Descriptor: INOSITOL HEXAKISPHOSPHATE, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide, Proteasome activator complex subunit 4, ...
Authors:Zhao, J.
Deposit date:2022-05-18
Release date:2022-11-02
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
5D8O
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BU of 5d8o by Molmil
1.90A resolution structure of BfrB (wild-type, C2221 form) from Pseudomonas aeruginosa
Descriptor: Ferroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Lovell, S, Battaile, K.P, Wang, Y, Yao, H, Rivera, M.
Deposit date:2015-08-17
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of the Bacterioferritin/Bacterioferritin Associated Ferredoxin Protein-Protein Interaction in Solution and Determination of Binding Energy Hot Spots.
Biochemistry, 54, 2015
5D8Q
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BU of 5d8q by Molmil
2.20A resolution structure of BfrB (L68A) from Pseudomonas aeruginosa
Descriptor: ARSENIC, Ferroxidase, MAGNESIUM ION, ...
Authors:Lovell, S, Battaile, K.P, Wang, Y, Yao, H, Rivera, M.
Deposit date:2015-08-17
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Characterization of the Bacterioferritin/Bacterioferritin Associated Ferredoxin Protein-Protein Interaction in Solution and Determination of Binding Energy Hot Spots.
Biochemistry, 54, 2015

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數據於2024-10-16公開中

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