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5OXI
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BU of 5oxi by Molmil
C-terminally retracted ubiquitin L67S mutant
Descriptor: SULFATE ION, Ubiquitin L67S mutant
Authors:Gladkova, C.G, Schubert, A.F, Wagstaff, J.L, Pruneda, J.N, Freund, S.M.V, Komander, D.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017
5OXH
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BU of 5oxh by Molmil
C-terminally retracted ubiquitin T66V/L67N mutant
Descriptor: SULFATE ION, Ubiquitin T66V/L67N mutant
Authors:Gladkova, C, Schubert, A.F, Wagstaff, J.L, Pruneda, J.P, Freund, S.M.V, Komander, D.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017
6EQI
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BU of 6eqi by Molmil
Structure of PINK1 bound to ubiquitin
Descriptor: GLYCEROL, Nb696, Serine/threonine-protein kinase PINK1, ...
Authors:Schubert, A.F, Gladkova, C, Pardon, E, Wagstaff, J.L, Freund, S.M.V, Steyaert, J, Maslen, S, Komander, D.
Deposit date:2017-10-13
Release date:2017-11-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of PINK1 in complex with its substrate ubiquitin.
Nature, 552, 2017
6FPQ
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BU of 6fpq by Molmil
Structure of S. pombe Mmi1 in complex with 7-mer RNA
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, RNA (5'-R(*UP*UP*AP*AP*AP*CP*C)-3'), YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-11
Release date:2018-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6FPX
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BU of 6fpx by Molmil
Structure of S. pombe Mmi1 in complex with 11-mer RNA
Descriptor: GLYCEROL, RNA (5'-R(P*UP*UP*UP*AP*AP*AP*CP*CP*UP*A)-3'), YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-12
Release date:2018-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6FPP
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BU of 6fpp by Molmil
Structure of S. pombe Mmi1
Descriptor: GLYCEROL, MAGNESIUM ION, YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-11
Release date:2018-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
5AF5
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BU of 5af5 by Molmil
Structure of Lys33-linked triUb S.G. P 212121
Descriptor: POLYUBIQUITIN-C
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
5AF4
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BU of 5af4 by Molmil
Structure of Lys33-linked diUb
Descriptor: GLYCEROL, SULFATE ION, UBIQUITIN
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
5AF6
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BU of 5af6 by Molmil
Structure of Lys33-linked diUb bound to Trabid NZF1
Descriptor: TRABID, UBIQUITIN, ZINC ION
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
4WZP
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BU of 4wzp by Molmil
Ser65 phosphorylated ubiquitin, major conformation
Descriptor: SULFATE ION, ubiquitin
Authors:Wauer, T, Wagstaff, J, Freund, S.M.V, Komander, D.
Deposit date:2014-11-20
Release date:2015-01-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.
Embo J., 34, 2015
6QIK
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BU of 6qik by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-01-20
Release date:2019-06-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6QT0
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BU of 6qt0 by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-02-22
Release date:2019-06-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6QTZ
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BU of 6qtz by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-02-26
Release date:2019-06-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
8QQF
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BU of 8qqf by Molmil
TBC1D23 PH domain complexed with STX16 TLY motif
Descriptor: GLYCEROL, PHOSPHATE ION, Syntaxin-16, ...
Authors:Kaufman, J.G, Owen, D.J.
Deposit date:2023-10-04
Release date:2024-04-10
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Cargo selective vesicle tethering: The structural basis for binding of specific cargo proteins by the Golgi tether component TBC1D23.
Sci Adv, 10, 2024
6HEM
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BU of 6hem by Molmil
Structure of the C-terminal domain of USP25 (748-1048)
Descriptor: GLYCEROL, SODIUM ION, Ubiquitin carboxyl-terminal hydrolase 25
Authors:Gersch, M, Komander, D.
Deposit date:2018-08-20
Release date:2019-03-27
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6HEJ
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BU of 6hej by Molmil
Structure of human USP28
Descriptor: SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 28
Authors:Gersch, M, Komander, D.
Deposit date:2018-08-20
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6HEH
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BU of 6heh by Molmil
Structure of the catalytic domain of USP28 (insertion deleted)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase 28,Ubiquitin carboxyl-terminal hydrolase 28
Authors:Gersch, M, Komander, D.
Deposit date:2018-08-20
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6HEI
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BU of 6hei by Molmil
Structure of the catalytic domain of USP28 (insertion deleted) bound to Ubiquitin-PA
Descriptor: 1,2-ETHANEDIOL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 28,Ubiquitin carboxyl-terminal hydrolase 28
Authors:Gersch, M, Komander, D.
Deposit date:2018-08-20
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6HEL
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BU of 6hel by Molmil
Structure of human USP25
Descriptor: Ubiquitin carboxyl-terminal hydrolase 25
Authors:Gersch, M, Komander, D.
Deposit date:2018-08-20
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.941 Å)
Cite:Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6HEK
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BU of 6hek by Molmil
Structure of human USP28 bound to Ubiquitin-PA
Descriptor: CHLORIDE ION, Polyubiquitin-B, TETRAETHYLENE GLYCOL, ...
Authors:Gersch, M, Komander, D.
Deposit date:2018-08-20
Release date:2019-03-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6RZZ
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BU of 6rzz by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-06-13
Release date:2019-06-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6RI5
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BU of 6ri5 by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S RNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-04-23
Release date:2019-06-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6S05
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BU of 6s05 by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-06-13
Release date:2019-06-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
8PPO
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BU of 8ppo by Molmil
First Intermediate Amyloid (FIA) - Tau
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D.
Deposit date:2023-07-07
Release date:2023-08-02
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q2J
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BU of 8q2j by Molmil
Tau - AD-MIA2
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-02
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.23 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024

 

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