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301D
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BU of 301d by Molmil
CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MG(II)-SOAKED
Descriptor: MAGNESIUM ION, RNA HAMMERHEAD RIBOZYME
Authors:Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A.
Deposit date:1996-12-14
Release date:1997-01-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
300D
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BU of 300d by Molmil
CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MN(II)-SOAKED
Descriptor: MANGANESE (II) ION, RNA HAMMERHEAD RIBOZYME
Authors:Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A.
Deposit date:1996-12-14
Release date:1997-01-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
299D
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BU of 299d by Molmil
CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: THE HAMMERHEAD RIBOZYME
Descriptor: RNA HAMMERHEAD RIBOZYME
Authors:Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A.
Deposit date:1996-12-14
Release date:1997-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme.
Science, 274, 1996
1MME
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BU of 1mme by Molmil
THE CRYSTAL STRUCTURE OF AN ALL-RNA HAMMERHEAD RIBOZYME: A PROPOSED MECHANISM FOR RNA CATALYTIC CLEAVAGE
Descriptor: RNA HAMMERHEAD RIBOZYME
Authors:Scott, W.G, Finch, J.T, Klug, A.
Deposit date:1995-12-09
Release date:1996-02-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage.
Cell(Cambridge,Mass.), 81, 1995
3ZD4
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BU of 3zd4 by Molmil
Full-Length Hammerhead Ribozyme with G12A substitution at the general base position
Descriptor: HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND
Authors:Scott, W.G, Schultz, E.
Deposit date:2012-11-24
Release date:2012-12-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Catalytic Effects of an Invariant Purine Substitution in the Hammerhead Ribozyme: Implications for the Mechanism of Acid-Base Catalysis.
Acta Crystallogr.,Sect.D, 70, 2014
2QUW
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BU of 2quw by Molmil
Hammerhead Ribozyme G12A mutant after cleavage
Descriptor: Hammerhead ribozyme, cleaved fragment, MAGNESIUM ION
Authors:Chi, Y.I, Scott, W.G, Kim, S.H.
Deposit date:2007-08-06
Release date:2008-07-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Capturing hammerhead ribozyme structures in action by modulating general base catalysis.
Plos Biol., 6, 2008
359D
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BU of 359d by Molmil
INHIBITION OF THE HAMMERHEAD RIBOZYME CLEAVAGE REACTION BY SITE-SPECIFIC BINDING OF TB(III)
Descriptor: RNA HAMMERHEAD RIBOZYME, TERBIUM(III) ION
Authors:Feig, A.L, Scott, W.G, Uhlenbeck, O.C.
Deposit date:1997-10-27
Release date:1997-11-07
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb.
Science, 279, 1998
4RNE
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BU of 4rne by Molmil
Structural variations and solvent structure of UGGGGU quadruplexes stabilized by Sr2+ ions
Descriptor: CALCIUM ION, RNA (5'-R(*UP*GP*GP*GP*GP*U)-3'), SODIUM ION, ...
Authors:Fyfe, A.C, Dunten, P.W, Scott, W.G.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr(2+) Ions.
J.Mol.Biol., 427, 2015
2VMK
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BU of 2vmk by Molmil
Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain
Descriptor: RIBONUCLEASE E, SULFATE ION, ZINC ION
Authors:Koslover, D.J, Callaghan, A.J, Marcaida, M.J, Martick, M, Scott, W.G, Luisi, B.F.
Deposit date:2008-01-28
Release date:2008-07-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
Structure, 16, 2008
2VRT
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BU of 2vrt by Molmil
Crystal Structure of E. coli RNase E possessing M1 RNA fragments - Catalytic Domain
Descriptor: 5'-R(*UP*UP)-3', 5'-R(*UP*UP*GP)-3', RIBONUCLEASE E, ...
Authors:Koslover, D.J, Callaghan, A.J, Marcaida, M.J, Garman, E.F, Martick, M, Scott, W.G, Luisi, B.F.
Deposit date:2008-04-14
Release date:2008-07-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
Structure, 16, 2008
379D
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BU of 379d by Molmil
THE STRUCTURAL BASIS OF HAMMERHEAD RIBOZYME SELF-CLEAVAGE
Descriptor: COBALT (II) ION, RNA (5'-R(*GP*GP*CP*CP*GP*AP*AP*AP*CP*UP*CP*GP*UP*AP*AP*GP*A P*GP*UP*CP*AP*CP*CP*AP*C)-3'), RNA (5'-R(*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3')
Authors:Murray, J.B, Terwey, D.P, Maloney, L, Karpeisky, A, Usman, N, Beigelman, L, Scott, W.G.
Deposit date:1998-02-05
Release date:1998-02-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural basis of hammerhead ribozyme self-cleavage.
Cell(Cambridge,Mass.), 92, 1998
5UNE
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BU of 5une by Molmil
Dimerized Structure Gives Further Insight Into the Function of the Novel RNA Gene: HAR1
Descriptor: MAGNESIUM ION, RNA (47-MER)
Authors:Lares, M, Scott, W.G.
Deposit date:2017-01-30
Release date:2017-03-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.900099 Å)
Cite:Dimerized Structure Gives Further Insight Into the Function of the Novel RNA Gene: HAR1
To Be Published
3ZP8
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BU of 3zp8 by Molmil
HIGH-RESOLUTION FULL-LENGTH HAMMERHEAD RIBOZYME
Descriptor: HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND, ...
Authors:Anderson, M, Schultz, E, Martick, M, Scott, W.G.
Deposit date:2013-02-26
Release date:2013-03-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Active-Site Monovalent Cations Revealed in a 1.55 A Resolution Hammerhead Ribozyme Structure
J.Mol.Biol., 425, 2013
3ZD5
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BU of 3zd5 by Molmil
THE 2.2 A STRUCTURE OF A FULL-LENGTH CATALYTICALLY ACTIVE HAMMERHEAD RIBOZYME
Descriptor: HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND
Authors:Martick, M, Scott, W.G.
Deposit date:2012-11-24
Release date:2012-12-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tertiary contacts distant from the active site prime a ribozyme for catalysis.
Cell, 126, 2006
488D
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BU of 488d by Molmil
CATALYTIC RNA ENZYME-PRODUCT COMPLEX
Descriptor: CADMIUM ION, FIRST RNA FRAGMENT OF CLEAVED SUBSTRATE, RNA RIBOZYME STRAND, ...
Authors:Murray, J.B, Szoke, H, Szoke, A, Scott, W.G.
Deposit date:2000-02-25
Release date:2000-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Capture and visualization of a catalytic RNA enzyme-product complex using crystal lattice trapping and X-ray holographic reconstruction.
Mol.Cell, 5, 2000
1XJR
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BU of 1xjr by Molmil
The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome
Descriptor: MAGNESIUM ION, s2m RNA
Authors:Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G.
Deposit date:2004-09-24
Release date:2005-02-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of a rigorously conserved RNA element within the SARS virus genome
Plos Biol., 3, 2005
2C0B
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BU of 2c0b by Molmil
Catalytic domain of E. coli RNase E in complex with 13-mer RNA
Descriptor: 5'-R(*UP*UP*UP*AP*CP*AP*GP*UP*AP*UP*UP*UP*G)-3', MAGNESIUM ION, RIBONUCLEASE E, ...
Authors:Marcaida, M.J, Callaghan, A.J, Scott, W.G, Luisi, B.F.
Deposit date:2005-08-30
Release date:2005-10-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
Nature, 437, 2005
2BX2
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BU of 2bx2 by Molmil
Catalytic domain of E. coli RNase E
Descriptor: MAGNESIUM ION, RIBONUCLEASE E, RNA (5'-R(*UP*UP*UP*AP*CP*AP*GP*UP*AP*UP*UP* UP*GP*UP*U)-3'), ...
Authors:Marcaida, M.J, Callaghan, A.J, Scott, W.G, Luisi, B.F.
Deposit date:2005-07-21
Release date:2005-10-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
Nature, 437, 2005
1Y28
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BU of 1y28 by Molmil
Crystal structure of the R220A metBJFIXL HEME domain
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, Sensor protein fixL
Authors:Dunham, C.M, Dioum, E.M, Tuckerman, J.R, Gonzalez, G, Scott, W.G, Gilles-Gonzalez, M.A.
Deposit date:2004-11-21
Release date:2004-12-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A distal arginine in the oxygen-sensing heme-PAS domains is essential to ligand binding, signal transduction, and structure
Biochemistry, 42, 2003
2OIU
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BU of 2oiu by Molmil
L1 Ribozyme Ligase circular adduct
Descriptor: L1 Ribozyme RNA Ligase, MAGNESIUM ION
Authors:Robertson, M.P, Scott, W.G.
Deposit date:2007-01-11
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural basis of ribozyme-catalyzed RNA assembly.
Science, 315, 2007
2OEU
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BU of 2oeu by Molmil
Full-length hammerhead ribozyme with Mn(II) bound
Descriptor: 5'-R(*GP*GP*CP*GP*UP*(OMC)P*CP*UP*GP*GP*(5BU)P*AP*UP*CP*CP*AP*AP*UP*CP*(DC))-3', Hammerhead Ribozyme, MANGANESE (II) ION
Authors:Martick, M, Scott, W.G.
Deposit date:2007-01-01
Release date:2007-02-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Solvent structure and hammerhead ribozyme catalysis.
Chem.Biol., 15, 2008
2QUS
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BU of 2qus by Molmil
Hammerhead Ribozyme G12A mutant pre-cleavage
Descriptor: Hammerhead ribozyme, MAGNESIUM ION
Authors:Chi, Y.I, Scott, W.G, Kim, S.H.
Deposit date:2007-08-06
Release date:2008-07-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Capturing hammerhead ribozyme structures in action by modulating general base catalysis.
Plos Biol., 6, 2008
1Q29
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BU of 1q29 by Molmil
Hammerhead Ribozyme with 5'-5' G-G linkage: Conformational change experiment
Descriptor: 5'-R(*GP*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3', COBALT (II) ION, Ribozyme
Authors:Dunham, C.M, Murray, J.B, Scott, W.G.
Deposit date:2003-07-23
Release date:2004-02-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme.
J.Mol.Biol., 332, 2003
1NYI
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BU of 1nyi by Molmil
Crosslinked Hammerhead Ribozyme Initial State
Descriptor: 5'-R(*GP*CP*CP*GP*AP*AP*AP*CP*UP*CP*GP*UP*AP*AP*GP*AP*GP*UP*CP*AP*CP*CP*AP*C)-3', 5'-R(P*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3', COBALT (II) ION, ...
Authors:Dunham, C.M, Murray, J.B, Scott, W.G.
Deposit date:2003-02-12
Release date:2004-02-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme.
J.Mol.Biol., 332, 2003
1IDC
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BU of 1idc by Molmil
ISOCITRATE DEHYDROGENASE FROM E.COLI (MUTANT K230M), STEADY-STATE INTERMEDIATE COMPLEX DETERMINED BY LAUE CRYSTALLOGRAPHY
Descriptor: 2-OXALOSUCCINIC ACID, ISOCITRATE DEHYDROGENASE, MAGNESIUM ION
Authors:Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
Deposit date:1995-01-18
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995

 

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