2GED
 
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4KF8
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4KF7
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5J1S
 | | TorsinA-LULL1 complex, H. sapiens, bound to VHH-BS2 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Demircioglu, F.E, Schwartz, T.U. | | Deposit date: | 2016-03-29 | | Release date: | 2016-08-17 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.399 Å) | | Cite: | Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.
Elife, 5, 2016
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4DXR
 | | Human SUN2-KASH1 complex | | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, Nesprin-1, POTASSIUM ION, ... | | Authors: | Sosa, B, Schwartz, T.U. | | Deposit date: | 2012-02-28 | | Release date: | 2012-06-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins.
Cell(Cambridge,Mass.), 149, 2012
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7TJC
 | | VHH Chl-B2 in complex with Chloramphenicol | | Descriptor: | CHLORAMPHENICOL, GLYCEROL, VHH-Chl-B2 | | Authors: | Nordeen, S.A, Schwartz, T.U. | | Deposit date: | 2022-01-16 | | Release date: | 2022-11-23 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Structure and specificity of an anti-chloramphenicol single domain antibody for detection of amphenicol residues.
Protein Sci., 31, 2022
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4TVS
 | | LAP1(aa356-583), H.sapiens, bound to VHH-BS1 | | Descriptor: | GLYCEROL, SULFATE ION, Torsin-1A-interacting protein 1, ... | | Authors: | Sosa, B.A, Schwartz, T.U. | | Deposit date: | 2014-06-27 | | Release date: | 2014-09-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | How lamina-associated polypeptide 1 (LAP1) activates Torsin.
Elife, 3, 2014
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1XKS
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5T0N
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2QX5
 | | Structure of nucleoporin Nic96 | | Descriptor: | CHLORIDE ION, Nucleoporin NIC96 | | Authors: | Jeudy, S, Schwartz, T.U. | | Deposit date: | 2007-08-10 | | Release date: | 2007-09-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of nucleoporin Nic96 reveals a novel, intricate helical domain architecture
J.Biol.Chem., 282, 2007
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5DJ4
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6OIF
 | | Cryo-EM structure of human TorsinA filament | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Torsin-1A | | Authors: | Zheng, W, Demircioglu, F.E, Schwartz, T.U, Egelman, E.H. | | Deposit date: | 2019-04-09 | | Release date: | 2019-07-24 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn.
Nat Commun, 10, 2019
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3MZK
 | | Sec13/Sec16 complex, S.cerevisiae | | Descriptor: | Protein transport protein SEC13, Protein transport protein SEC16 | | Authors: | Whittle, J.R, Schwartz, T.U. | | Deposit date: | 2010-05-12 | | Release date: | 2010-08-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structure of the Sec13-Sec16 edge element, a template for assembly of the COPII vesicle coat.
J.Cell Biol., 190, 2010
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3MZL
 | | Sec13/Sec31 edge element, loop deletion mutant | | Descriptor: | Protein transport protein SEC13, Protein transport protein SEC31 | | Authors: | Whittle, J.R, Schwartz, T.U. | | Deposit date: | 2010-05-12 | | Release date: | 2010-08-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the Sec13-Sec16 edge element, a template for assembly of the COPII vesicle coat.
J.Cell Biol., 190, 2010
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5I2C
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7PEQ
 | | Model of the outer rings of the human nuclear pore complex | | Descriptor: | Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133, Nuclear pore complex protein Nup160, ... | | Authors: | Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U. | | Deposit date: | 2021-08-11 | | Release date: | 2021-10-20 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
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7PER
 | | Model of the inner ring of the human nuclear pore complex | | Descriptor: | Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ... | | Authors: | Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U. | | Deposit date: | 2021-08-11 | | Release date: | 2021-10-20 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
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5JJ7
 | | Fic-1 (aa134 - 508 E274G) from C. elegans | | Descriptor: | Adenosine monophosphate-protein transferase FICD homolog, SULFATE ION | | Authors: | Cruz, V.E, Schwartz, T.U. | | Deposit date: | 2016-04-22 | | Release date: | 2016-06-01 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.749 Å) | | Cite: | Fic-1 (aa134 - 508 E274G) from C. elegans
To be published
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5JJ6
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5J1T
 | | TorsinAdeltaE-LULL1 complex, H. sapiens, bound to VHH-BS2 | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Demircioglu, F.E, Schwartz, T.U. | | Deposit date: | 2016-03-29 | | Release date: | 2016-08-17 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.402 Å) | | Cite: | Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.
Elife, 5, 2016
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3CQG
 | | Nucleoporin Nup107/Nup133 interaction complex, delta finger mutant | | Descriptor: | Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133 | | Authors: | Jeudy, S, Boehmer, T, Berke, I, Schwartz, T.U. | | Deposit date: | 2008-04-02 | | Release date: | 2008-07-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural and functional studies of Nup107/Nup133 interaction and its implications for the architecture of the nuclear pore complex.
Mol.Cell, 30, 2008
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3EWE
 | | Crystal Structure of the Nup85/Seh1 Complex | | Descriptor: | Nucleoporin NUP85, Nucleoporin SEH1 | | Authors: | Brohawn, S.G, Leksa, N.C, Rajashankar, K.R, Schwartz, T.U. | | Deposit date: | 2008-10-14 | | Release date: | 2008-11-11 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural evidence for common ancestry of the nuclear pore complex and vesicle coats.
Science, 322, 2008
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3CQC
 | | Nucleoporin Nup107/Nup133 interaction complex | | Descriptor: | Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133 | | Authors: | Jeudy, S, Boehmer, T, Berke, I, Schwartz, T.U. | | Deposit date: | 2008-04-02 | | Release date: | 2008-07-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Structural and functional studies of Nup107/Nup133 interaction and its implications for the architecture of the nuclear pore complex.
Mol.Cell, 30, 2008
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3GJ0
 | | Crystal structure of human RanGDP | | Descriptor: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Partridge, J.R, Schwartz, T.U. | | Deposit date: | 2009-03-07 | | Release date: | 2009-08-04 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain.
J.Mol.Biol., 391, 2009
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5TJW
 | | Influenza A virus Nucleoprotein in Complex with Inhibitory Nanobody | | Descriptor: | NP-specific inhibitory VHH, Nucleoprotein | | Authors: | Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U. | | Deposit date: | 2016-10-05 | | Release date: | 2016-12-21 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.231 Å) | | Cite: | The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment.
MBio, 7, 2016
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