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Structure of ULK1 bound to a potent inhibitor
Descriptor:	GLYCEROL, N~2~-(1H-benzimidazol-6-yl)-N~4~-(5-cyclobutyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine, Serine/threonine-protein kinase ULK1
Authors:	Lazarus, M.B, Novotny, C.J, Shokat, K.M.
Deposit date:	2014-10-14
Release date:	2015-01-14
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (1.88 Å)
Cite:	Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors. Acs Chem.Biol., 10, 2015

Structure of ULK1 bound to an inhibitor
Descriptor:	N~2~-(4-aminophenyl)-N~4~-(5-cyclopropyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine, Serine/threonine-protein kinase ULK1
Authors:	Lazarus, M.B, Novotny, C.J, Shokat, K.M.
Deposit date:	2014-10-14
Release date:	2015-01-14
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.56 Å)
Cite:	Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors. Acs Chem.Biol., 10, 2015

Crystal structure of EGFR tyrosine kinase domain with novel inhibitor of active state of HER2
Descriptor:	3-(furan-2-yl)-N-[5-(furan-2-yl)-2-methoxyphenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Epidermal growth factor receptor, SULFATE ION
Authors:	Park, J.H, Lemmon, M.A.
Deposit date:	2016-04-18
Release date:	2016-09-07
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (3.298 Å)
Cite:	Overcoming resistance to HER2 inhibitors through state-specific kinase binding. Nat.Chem.Biol., 12, 2016