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6R5G
C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
Descriptor:
ITSM, Tyrosine-protein phosphatase non-receptor type 11
Authors:
Marasco, M.
Deposit date:
2019-03-25
Release date:
2020-02-05
Last modified:
2023-06-14
Method:
SOLUTION NMR
Cite:
Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
6ROY
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based inhibitory motif
Descriptor:
Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based inhibitory motif (ITIM)
Authors:
Krausze, J
,
Sikorska, J
,
Carlomagno, T.
Deposit date:
2019-05-13
Release date:
2020-02-19
Last modified:
2024-01-24
Method:
X-RAY DIFFRACTION (2.1 Å)
Cite:
Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
6ROZ
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based switch motif
Descriptor:
Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based switch motif (ITSM)
Authors:
Krausze, J
,
Sikorska, J
,
Carlomagno, T.
Deposit date:
2019-05-13
Release date:
2020-02-19
Last modified:
2024-01-24
Method:
X-RAY DIFFRACTION (2.89 Å)
Cite:
Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
7NXE
Structure of the Phospholipase C gamma 1 tSH2 domain in complex with a phosphorylated KSHV pK15 peptide
Descriptor:
Isoform 2 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, Protein K15
Authors:
Ssebyatika, G
,
Krey, T.
Deposit date:
2021-03-18
Release date:
2021-06-09
Last modified:
2024-01-31
Method:
X-RAY DIFFRACTION (2.1 Å)
Cite:
Recruitment of phospholipase C gamma 1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation.
Plos Pathog., 17, 2021
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224931
数据于2024-09-11公开中