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2N99
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BU of 2n99 by Molmil
Solution structure of the SLURP-2, a secreted isoform of Lynx1
Descriptor: Ly-6/neurotoxin-like protein 1
Authors:Paramonov, A.S, Shenkarev, Z.O, Lyukmanova, E.N, Arseniev, A.S.
Deposit date:2015-11-11
Release date:2016-09-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors.
Sci Rep, 6, 2016
5LUE
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BU of 5lue by Molmil
Minor form of the recombinant cytotoxin-1 from N. oxiana
Descriptor: VC-1=CYTOTOXIN
Authors:Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G.
Deposit date:2016-09-08
Release date:2017-09-20
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
7ZJL
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BU of 7zjl by Molmil
Delta SARS-CoV-2 spike protein in complex with REGN10987 Fab homologue.
Descriptor: REGN10987 Fab homologue (Heavy chain), REGN10987 Fab homologue (Light chain), Spike glycoprotein
Authors:Pichkur, E.B, Lyukmanova, E.N, Shenkarev, Z.O.
Deposit date:2022-04-11
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Delta SARS-CoV-2 spike protein in complex with REGN10987 Fab homologue.
To Be Published
6IB6
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BU of 6ib6 by Molmil
Solution structure of the water-soluble LU-domain of human Lypd6 protein
Descriptor: Ly6/PLAUR domain-containing protein 6
Authors:Tsarev, A.V, Kulbatskii, D.S, Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O.
Deposit date:2018-11-29
Release date:2019-12-18
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Int J Mol Sci, 21, 2020
8P1H
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BU of 8p1h by Molmil
Crystal structure of the chimera of human 14-3-3 zeta and phosphorylated cytoplasmic loop fragment of the alpha7 acetylcholine receptor
Descriptor: 1,2-ETHANEDIOL, AZIDE ION, BENZOIC ACID, ...
Authors:Boyko, K.M, Kapitonova, A.A, Tugaeva, K.V, Varfolomeeva, L.A, Lyukmanova, E.N, Sluchanko, N.N.
Deposit date:2023-05-12
Release date:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure reveals canonical recognition of the phosphorylated cytoplasmic loop of human alpha7 nicotinic acetylcholine receptor by 14-3-3 protein.
Biochem.Biophys.Res.Commun., 682, 2023
6ZSS
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BU of 6zss by Molmil
NMR structure of water-soluble domain of human Lynx2 (Lypd1) protein
Descriptor: Ly6/PLAUR domain-containing protein 1
Authors:Kocharovskaya, M.V, Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O.
Deposit date:2020-07-16
Release date:2021-01-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Int J Mol Sci, 21, 2020
6ZZE
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BU of 6zze by Molmil
Structure of the trans-(Tyr39-Pro40) form of the Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1)
Descriptor: Secreted Ly-6/uPAR-related protein 1
Authors:Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O.
Deposit date:2020-08-04
Release date:2021-01-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Int J Mol Sci, 21, 2020
6ZZF
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BU of 6zzf by Molmil
Structure of the cis-(Tyr39-Pro40) form of the Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1)
Descriptor: Secreted Ly-6/uPAR-related protein 1
Authors:Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O.
Deposit date:2020-08-04
Release date:2021-01-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Int J Mol Sci, 21, 2020
6ZSO
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BU of 6zso by Molmil
Solution structure of the water-soluble LU-domain of human Lypd6b protein
Descriptor: Ly6/PLAUR domain-containing protein 6B
Authors:Tsarev, A.V, Kulbatskii, D.S, Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O.
Deposit date:2020-07-16
Release date:2021-01-13
Method:SOLUTION NMR
Cite:Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Int J Mol Sci, 21, 2020
5T8A
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BU of 5t8a by Molmil
Recombinant cytotoxin-I from the venom of cobra N. oxiana
Descriptor: Cytotoxin 1
Authors:Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G.
Deposit date:2016-09-07
Release date:2017-09-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
2MJ4
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BU of 2mj4 by Molmil
Neurotoxin II from snake venom Naja Oxiana in solution
Descriptor: Short neurotoxin 1
Authors:Lesovoy, D.M, Nolde, S.B, Bocharov, E.V, Lyukmanova, E.N, Arseniev, A.S.
Deposit date:2013-12-26
Release date:2015-01-28
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:An NMR-based approach for validation of protein side-chains dynamics in silico
To be Published
2M59
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BU of 2m59 by Molmil
Spatial structure of dimeric VEGFR2 membrane domain in DPC micelles
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Mineev, K.S, Arseniev, A.S, Shulepko, M.A, Lyukmanova, E.N.
Deposit date:2013-02-19
Release date:2014-03-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation.
Structure, 22, 2014
2MET
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BU of 2met by Molmil
NMR spatial structure of the trimeric mutant TM domain of VEGFR2 receptor.
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Mineev, K.S, Arseniev, A.A, Shulepko, M, Lyukmanova, E.N, Kirpichnikov, M.P.
Deposit date:2013-10-02
Release date:2014-07-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation
Structure, 22, 2014
2MEU
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BU of 2meu by Molmil
NMR spatial structure of mutant dimeric TM domain of VEGFR2 receptor
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Mineev, K.S, Arseniev, A.S, Lyukmanova, E.N, Shulepko, M.A, Kirpichnikov, M.P.
Deposit date:2013-10-02
Release date:2014-07-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation
Structure, 22, 2014
2MJ0
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BU of 2mj0 by Molmil
Spatial structure of P33A mutant of non-conventional toxin WTX from Naja kaouthia
Descriptor: Weak tryptophan-containing neurotoxin
Authors:Paramonov, A.S, Shenkarev, Z.O, Lyukmanova, E.N.
Deposit date:2013-12-23
Release date:2014-12-24
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Interaction of Weak Toxin from Naja kaouthia with Muscarinic Acetylcholine Receptors: Mutagenesis, NMR and Modeling Study
To be Published
8BWB
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BU of 8bwb by Molmil
Spider toxin Pha1b (PnTx3-6) from Phoneutria nigriventer targeting CaV2.x calcium channels and TRPA1 channel
Descriptor: Omega-ctenitoxin-Pn4a
Authors:Mironov, P.A, Chernaya, E.M, Paramonov, A.S, Shenkarev, Z.O.
Deposit date:2022-12-06
Release date:2023-06-21
Last modified:2023-07-05
Method:SOLUTION NMR
Cite:Recombinant Production, NMR Solution Structure, and Membrane Interaction of the Ph alpha 1 beta Toxin, a TRPA1 Modulator from the Brazilian Armed Spider Phoneutria nigriventer .
Toxins, 15, 2023
2L03
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BU of 2l03 by Molmil
Spatial structure of water-soluble Lynx1
Descriptor: Ly-6/neurotoxin-like protein 1
Authors:Mineev, K.S, Shenkarev, Z.O, Arseniev, A.S.
Deposit date:2010-06-30
Release date:2011-01-19
Last modified:2014-10-01
Method:SOLUTION NMR
Cite:NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1
J.Biol.Chem., 286, 2011
5NPN
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BU of 5npn by Molmil
Refined structure of cytotoxin I
Descriptor: Cytotoxin 1
Authors:Dubinnyi, M.A, Dubovskii, P.V, Arseniev, A.S.
Deposit date:2017-04-17
Release date:2018-04-04
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
7PVB
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BU of 7pvb by Molmil
Structure of Viscotoxin A3 from Viscum Album in the complex with DPC micelles
Descriptor: Viscotoxin-A3
Authors:Paramonov, A.S, Shenkarev, Z.O.
Deposit date:2021-10-01
Release date:2021-12-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Spatial structure and oligomerization of viscotoxin A3 in detergent micelles: Implication for mechanisms of ion channel formation and membrane lysis.
Biochem.Biophys.Res.Commun., 585, 2021
2JWM
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BU of 2jwm by Molmil
NMR spatial srtucture of ternary complex kalata B7/Mn2+/DPC micelle
Descriptor: Kalata-B7
Authors:Nadezhdin, K.D, Shenkarev, Z.O, Skjeldal, L, Arseniev, A.S.
Deposit date:2007-10-16
Release date:2008-03-11
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Divalent cation coordination and mode of membrane interaction in cyclotides: NMR spatial structure of ternary complex Kalata B7/Mn(2+)/DPC micelle
J.Inorg.Biochem., 102, 2008
2MQU
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BU of 2mqu by Molmil
Spatial structure of Hm-3, a membrane-active spider toxin affecting sodium channels
Descriptor: Neurotoxin Hm-3
Authors:Myshkin, M.Y, Shenkarev, Z.O, Paramonov, A.S, Berkut, A.A, Grishin, E.V, Vassilevski, A.A.
Deposit date:2014-06-27
Release date:2014-11-05
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Structure of membrane-active toxin from crab spider Heriaeus melloteei suggests parallel evolution of sodium channel gating modifiers in Araneomorphae and Mygalomorphae.
J. Biol. Chem., 290, 2015
2L9U
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BU of 2l9u by Molmil
Spatial structure of dimeric ErbB3 transmembrane domain
Descriptor: Receptor tyrosine-protein kinase erbB-3
Authors:Mineev, K.S, Arseniev, A.S.
Deposit date:2011-02-24
Release date:2011-05-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Spatial structure and dimer--monomer equilibrium of the ErbB3 transmembrane domain in DPC micelles.
Biochim. Biophys. Acta, 1808, 2011
2M1F
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BU of 2m1f by Molmil
NMR Structure of Antiamoebin I (peptaibol antibiotic) bound to DMPC/DHPC bicelles
Descriptor: Antiamoebin I
Authors:Shenkarev, Z.O, Paramonov, A.S, Gizatullina, A.K.
Deposit date:2012-11-27
Release date:2012-12-12
Last modified:2013-10-02
Method:SOLUTION NMR
Cite:Peptaibol antiamoebin I: spatial structure, backbone dynamics, interaction with bicelles and lipid-protein nanodiscs, and pore formation in context of barrel-stave model.
Chem.Biodivers., 10, 2013

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数据于2024-10-30公开中

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