8BWB
Spider toxin Pha1b (PnTx3-6) from Phoneutria nigriventer targeting CaV2.x calcium channels and TRPA1 channel
Summary for 8BWB
| Entry DOI | 10.2210/pdb8bwb/pdb |
| NMR Information | BMRB: 34776 |
| Descriptor | Omega-ctenitoxin-Pn4a (1 entity in total) |
| Functional Keywords | toxin, spider toxin, neurotoxin, cystine-knot peptide, antagonist of cav2.x calcium channels and trpa1 channel |
| Biological source | Phoneutria nigriventer (Brazilian armed spider) |
| Total number of polymer chains | 1 |
| Total formula weight | 6055.09 |
| Authors | Mironov, P.A.,Chernaya, E.M.,Paramonov, A.S.,Shenkarev, Z.O. (deposition date: 2022-12-06, release date: 2023-06-21, Last modification date: 2023-07-05) |
| Primary citation | Lyukmanova, E.N.,Mironov, P.A.,Kulbatskii, D.S.,Shulepko, M.A.,Paramonov, A.S.,Chernaya, E.M.,Logashina, Y.A.,Andreev, Y.A.,Kirpichnikov, M.P.,Shenkarev, Z.O. Recombinant Production, NMR Solution Structure, and Membrane Interaction of the Ph alpha 1 beta Toxin, a TRPA1 Modulator from the Brazilian Armed Spider Phoneutria nigriventer . Toxins, 15:-, 2023 Cited by PubMed: 37368679DOI: 10.3390/toxins15060378 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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