3ZVZ
| PHD finger of human UHRF1 | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE UHRF1, ZINC ION | Authors: | Lallous, N, Birck, C, Mc Ewen, A.G, Legrand, P, Samama, J.P. | Deposit date: | 2011-07-28 | Release date: | 2011-11-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | The Phd Finger of Human Uhrf1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers. Plos One, 6, 2011
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3ZVY
| PHD finger of human UHRF1 in complex with unmodified histone H3 N- terminal tail | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE UHRF1, ... | Authors: | Lallous, N, Birck, C, Mc Ewen, A.G, Legrand, P, Samama, J.P. | Deposit date: | 2011-07-28 | Release date: | 2011-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Phd Finger of Human Uhrf1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers. Plos One, 6, 2011
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8E1A
| Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors | Descriptor: | 1,2-ETHANEDIOL, 4-[4-(3-fluoro-2-methoxyphenyl)-1,3-thiazol-2-yl]morpholine, Androgen receptor | Authors: | Lallous, N, Li, H, Radaeva, M, Dalal, K, Leblanc, E, Ban, F, Ciesielski, F, Chow, B, Morin, M, Singh, K, Rennie, P.S, Cherkasov, A. | Deposit date: | 2022-08-10 | Release date: | 2022-09-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors. Cells, 11, 2022
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4C6C
| Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from HEK293 cells. | Descriptor: | CAD PROTEIN, FORMIC ACID, ZINC ION | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-01-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.451 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6N
| Crystal structure of the dihydroorotase domain of human CAD E1637T mutant bound to substrate at pH 6.0 | Descriptor: | CAD PROTEIN, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6E
| Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 5.5 | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, DIHYDROOROTASE, FORMIC ACID, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.263 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6O
| Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 6.0 | Descriptor: | CAD PROTEIN, FORMIC ACID, ZINC ION | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6M
| Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 7.0 | Descriptor: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-01-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6K
| Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 8.0 | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.478 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6I
| Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 7.0 | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-01-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6D
| Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.0 | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.298 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4BY3
| Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from E. coli. | Descriptor: | DIHYDROOROTASE, FORMIC ACID, ZINC ION | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-07-17 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6L
| Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 6.0 | Descriptor: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6B
| Crystal structure of the dihydroorotase domain of human CAD with incomplete active site, obtained recombinantly from E. coli. | Descriptor: | CAD PROTEIN, FORMIC ACID, GLYCEROL | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.656 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6P
| Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 7.0 | Descriptor: | CAD PROTEIN, FORMIC ACID, ZINC ION | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.518 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6Q
| Crystal structure of the dihydroorotase domain of human CAD C1613S mutant bound to substrate at pH 7.0 | Descriptor: | CAD PROTEIN, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.659 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6J
| Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 7.5 | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.299 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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4C6F
| Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.5 | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, DIHYDROOROTASE, FORMIC ACID, ... | Authors: | Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. | Deposit date: | 2013-09-18 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.261 Å) | Cite: | Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
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6DV5
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5G1O
| Aspartate transcarbamoylase domain of human CAD in apo form | Descriptor: | 1,2-ETHANEDIOL, CAD protein, GLYCEROL | Authors: | Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S. | Deposit date: | 2016-03-29 | Release date: | 2016-06-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala. Structure, 24, 2016
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5G1P
| Aspartate transcarbamoylase domain of human CAD bound to carbamoyl phosphate | Descriptor: | CAD PROTEIN, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER | Authors: | Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S. | Deposit date: | 2016-03-29 | Release date: | 2016-06-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala. Structure, 24, 2016
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5G1N
| Aspartate transcarbamoylase domain of human CAD bound to PALA | Descriptor: | 1,2-ETHANEDIOL, CAD PROTEIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID | Authors: | Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S. | Deposit date: | 2016-03-29 | Release date: | 2016-06-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala. Structure, 24, 2016
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