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6W4X
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BU of 6w4x by Molmil
Holocomplex of E. coli class Ia ribonucleotide reductase with GDP and TTP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MU-OXO-DIIRON, ...
Authors:Kang, G, Taguchi, A, Stubbe, J, Drennan, C.L.
Deposit date:2020-03-11
Release date:2020-04-08
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex.
Science, 368, 2020
8EIZ
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BU of 8eiz by Molmil
Cryo-EM structure of squid sensory receptor CRB1
Descriptor: N-benzyl-2-(2,6-dimethylanilino)-N,N-diethyl-2-oxoethan-1-aminium, Squid sensory receptor CRB1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Kang, G, Kim, J.J, Allard, C.A.H, Valencia-Montoya, W.A, van Giesen, L, Kilian, P.B, Bai, X, Bellono, N.W, Hibbs, R.E.
Deposit date:2022-09-15
Release date:2023-04-12
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Sensory specializations drive octopus and squid behaviour.
Nature, 616, 2023
8EIS
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BU of 8eis by Molmil
Cryo-EM structure of octopus sensory receptor CRT1
Descriptor: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Octopus sensory receptor
Authors:Kang, G, Kim, J.J, Allard, C.A.H, Valencia-Montoya, W.A, Bellono, N.W, Hibbs, R.E.
Deposit date:2022-09-15
Release date:2023-04-12
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Sensory specializations drive octopus and squid behaviour.
Nature, 616, 2023
8SSZ
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BU of 8ssz by Molmil
The 2alpha3beta stoichiometry of full-length human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine and calcium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, CALCIUM ION, ...
Authors:Kang, G, Hibbs, R.E.
Deposit date:2023-05-09
Release date:2024-02-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Br.J.Pharmacol., 181, 2024
8ST3
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BU of 8st3 by Molmil
The 2alpha3beta stoichiometry of human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine and calcium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, CALCIUM ION, ...
Authors:Kang, G, Hibbs, R.E.
Deposit date:2023-05-09
Release date:2024-02-07
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Br.J.Pharmacol., 181, 2024
8ST0
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BU of 8st0 by Molmil
The 2alpha3beta stoichiometry of full-length human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, IgG1 Heavy Chain, ...
Authors:Kang, G, Hibbs, R.E.
Deposit date:2023-05-09
Release date:2024-02-07
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Br.J.Pharmacol., 181, 2024
8ST1
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BU of 8st1 by Molmil
The 3alpha2beta stoichiometry of human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine and calcium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, CALCIUM ION, ...
Authors:Kang, G, Hibbs, R.E.
Deposit date:2023-05-09
Release date:2024-02-07
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Br.J.Pharmacol., 181, 2024
8ST2
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BU of 8st2 by Molmil
The 3alpha2beta stoichiometry of human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, IgG1 Heavy Chain, ...
Authors:Kang, G, Hibbs, R.E.
Deposit date:2023-05-09
Release date:2024-02-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Br.J.Pharmacol., 181, 2024
8ST4
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BU of 8st4 by Molmil
The 2alpha3beta stoichiometry of human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, IgG1 Heavy Chain, ...
Authors:Kang, G, Hibbs, R.E.
Deposit date:2023-05-09
Release date:2024-02-07
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Br.J.Pharmacol., 181, 2024
5C8F
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BU of 5c8f by Molmil
Crystal structure of light-exposed full-length Thermus thermophilus CarH bound to cobalamin
Descriptor: CHLORIDE ION, COBALAMIN, GLYCEROL, ...
Authors:Jost, M, Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
5C8A
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BU of 5c8a by Molmil
Crystal structure of a truncated form of Thermus thermophilus CarH bound to adenosylcobalamin (dark state)
Descriptor: 5'-DEOXYADENOSINE, COBALAMIN, GLYCEROL, ...
Authors:Jost, M, Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
8STA
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BU of 8sta by Molmil
Isobutyryl-CoA mutase fused in the presence of GMPPCP
Descriptor: Isobutyryl-CoA mutase fused
Authors:Vaccaro, F.A, Drennan, C.L.
Deposit date:2023-05-09
Release date:2023-08-09
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structural insight into G-protein chaperone-mediated maturation of a bacterial adenosylcobalamin-dependent mutase.
J.Biol.Chem., 299, 2023
8SSL
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BU of 8ssl by Molmil
Isobutyryl-CoA mutase fused Q341A in the presence of GTP
Descriptor: Fused isobutyryl-CoA mutase, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Vaccaro, F.A, Drennan, C.L.
Deposit date:2023-05-08
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insight into G-protein chaperone-mediated maturation of a bacterial adenosylcobalamin-dependent mutase.
J.Biol.Chem., 299, 2023
9DB2
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BU of 9db2 by Molmil
Class Ia ribonucleotide reductase with mechanism-based inhibitor N3CDP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 4-amino-1-{(3xi)-3-C-amino-2-deoxy-5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-beta-D-threo-pentofuranosyl}pyrimidin-2(1H)-one, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Westmoreland, D.E, Drennan, C.L.
Deposit date:2024-08-23
Release date:2024-11-06
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:2.6- angstrom resolution cryo-EM structure of a class Ia ribonucleotide reductase trapped with mechanism-based inhibitor N 3 CDP.
Proc.Natl.Acad.Sci.USA, 121, 2024
5TK9
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BU of 5tk9 by Molmil
Structure of the HD-domain phosphohydrolase OxsA with Oxetanocin-A bound
Descriptor: MAGNESIUM ION, OxsA protein, [(2S,3R,4R)-4-(6-amino-9H-purin-9-yl)oxetane-2,3-diyl]dimethanol
Authors:Bridwell-Rabb, J, Drennan, C.L.
Deposit date:2016-10-06
Release date:2016-11-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.843 Å)
Cite:An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5TK8
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BU of 5tk8 by Molmil
Structure of the HD-domain phosphohydrolase OxsA with Oxetanocin-A monophosphate bound
Descriptor: MAGNESIUM ION, OxsA protein, [(2S,3R,4R)-4-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)oxetan-2-yl]methyl dihydrogen phosphate
Authors:Bridwell-Rabb, J, Drennan, C.L.
Deposit date:2016-10-06
Release date:2016-11-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
7JX4
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BU of 7jx4 by Molmil
Crystal Structure of N-Lysine Peptoid-modified Collagen Triple Helix
Descriptor: Collagen mimetic peptide with N-Lysine guest
Authors:Yu, M.S, Whitby, F.G, Hill, C.P, Kessler, J.L, Yang, L.D.
Deposit date:2020-08-26
Release date:2021-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Peptoid Residues Make Diverse, Hyperstable Collagen Triple-Helices.
J.Am.Chem.Soc., 143, 2021
7JX5
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BU of 7jx5 by Molmil
Crystal Structure of N-Phenylalanine Peptoid-modified Collagen Triple Helix
Descriptor: Collagen mimetic peptide with N-Phenylalanine guest
Authors:Yu, M.S, Whitby, F.G, Hill, C.P, Kessler, J.L, Yang, L.D.
Deposit date:2020-08-26
Release date:2021-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Peptoid Residues Make Diverse, Hyperstable Collagen Triple-Helices
J.Am.Chem.Soc., 143, 2021
5CNV
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BU of 5cnv by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to GDP and TTP at 3.20 Angstroms resolution
Descriptor: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L.
Deposit date:2015-07-18
Release date:2016-01-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli.
Elife, 5, 2016
5C8E
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BU of 5c8e by Molmil
Crystal structure of Thermus thermophilus CarH bound to adenosylcobalamin and a 26-bp DNA segment
Descriptor: 26-mer DNA segment containing the CarH operator sequence (antisense strand), 26-mer DNA segment containing the CarH operator sequence (sense strand), 5'-DEOXYADENOSINE, ...
Authors:Jost, M, Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.89 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
5C8D
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BU of 5c8d by Molmil
Crystal structure of full-length Thermus thermophilus CarH bound to adenosylcobalamin (dark state)
Descriptor: 5'-DEOXYADENOSINE, COBALAMIN, Light-dependent transcriptional regulator CarH
Authors:Jost, M, Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
5CNS
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BU of 5cns by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to CDP and dATP at 2.97 Angstroms resolution
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, ...
Authors:Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L.
Deposit date:2015-07-18
Release date:2016-01-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.975 Å)
Cite:Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli.
Elife, 5, 2016
5CNT
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BU of 5cnt by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, MU-OXO-DIIRON, ...
Authors:Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L.
Deposit date:2015-07-18
Release date:2016-01-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli.
Elife, 5, 2016
5CNU
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BU of 5cnu by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to ADP and dGTP at 3.40 Angstroms resolution
Descriptor: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L.
Deposit date:2015-07-18
Release date:2016-01-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli.
Elife, 5, 2016
5TK7
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BU of 5tk7 by Molmil
Structure of the HD-domain phosphohydrolase OxsA with Oxetanocin-A triphosphate bound
Descriptor: MAGNESIUM ION, OxsA protein, [[(2~{S},3~{R},4~{R})-4-(6-aminopurin-9-yl)-3-(hydroxymethyl)oxetan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
Authors:Bridwell-Rabb, J, Drennan, C.L.
Deposit date:2016-10-06
Release date:2016-11-16
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016

 

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