2D2H
 
 | | OpdA from Agrobacterium radiobacter with bound inhibitor trimethyl phosphate at 1.8 A resolution | | Descriptor: | COBALT (II) ION, TRIMETHYL PHOSPHATE, phosphotriesterase | | Authors: | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | | Deposit date: | 2005-09-09 | | Release date: | 2005-09-20 | | Last modified: | 2015-08-19 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism
Biochim.Biophys.Acta, 1752, 2005
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2D2G
 | | OpdA from Agrobacterium radiobacter with bound product dimethylthiophosphate | | Descriptor: | COBALT (II) ION, O,O-DIMETHYL HYDROGEN THIOPHOSPHATE, phosphotriesterase | | Authors: | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | | Deposit date: | 2005-09-08 | | Release date: | 2005-09-20 | | Last modified: | 2015-08-19 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism
Biochim.Biophys.Acta, 1752, 2005
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2D2J
 | | OpdA from Agrobacterium radiobacter without inhibitor/product present at 1.75 A resolution | | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, phosphotriesterase | | Authors: | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | | Deposit date: | 2005-09-09 | | Release date: | 2005-09-20 | | Last modified: | 2015-08-19 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism
Biochim.Biophys.Acta, 1752, 2005
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6MMO
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6MMQ
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6MMC
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6MM2
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8VE9
 | | IsPETase - ACCCETN mutant - CombiPETase | | Descriptor: | CHLORIDE ION, GLYCEROL, Poly(ethylene terephthalate) hydrolase | | Authors: | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | Deposit date: | 2023-12-18 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem, 25, 2024
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8VEM
 | | IsPETase - ACCE mutant | | Descriptor: | Poly(ethylene terephthalate) hydrolase, SULFATE ION | | Authors: | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | Deposit date: | 2023-12-19 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.711 Å) | | Cite: | Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem, 25, 2024
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8VEL
 | | IsPETase - ACCCC mutant | | Descriptor: | Poly(ethylene terephthalate) hydrolase, SULFATE ION | | Authors: | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | Deposit date: | 2023-12-19 | | Release date: | 2024-06-19 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.624 Å) | | Cite: | Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem, 25, 2024
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8VEK
 | | IsPETase - ACC mutant | | Descriptor: | GLYCEROL, Poly(ethylene terephthalate) hydrolase, SULFATE ION | | Authors: | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | Deposit date: | 2023-12-19 | | Release date: | 2024-06-19 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.14 Å) | | Cite: | Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem, 25, 2024
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8OUK
 | | Arf GTPase from the asgard Hodarchaea : HodArfR1 bound to GTP | | Descriptor: | Arf GTPase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | Authors: | Menetrey, J, Jackson, C, Dacks, J, Elias, M, Vargova, R. | | Deposit date: | 2023-04-23 | | Release date: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Arf Family GTPases are present in Asgard archaea
To Be Published
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6N4A
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6NTB
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5IKX
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7MSQ
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8CRU
 | | PETase Ancestral Sequence Reconstruction 008 | | Descriptor: | CITRIC ACID, Poly(ethylene terephthalate) hydrolase | | Authors: | Joho, Y, Royan, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | Deposit date: | 2022-05-11 | | Release date: | 2022-09-21 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability and Activity.
Biochemistry, 62, 2023
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8D4W
 | | Asymmetric ene-reduction of alpha,beta-unsaturated compounds using MSMEG_2850 | | Descriptor: | Cell entry (Mce) related family protein, DI(HYDROXYETHYL)ETHER, GLYCEROL | | Authors: | Kang, S.W, Frkic, R.L, Jackson, C. | | Deposit date: | 2022-06-02 | | Release date: | 2023-01-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Asymmetric Ene-Reduction of alpha , beta-Unsaturated Compounds by F 420 -Dependent Oxidoreductases A Enzymes from Mycobacterium smegmatis .
Biochemistry, 62, 2023
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5JQJ
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5K4M
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6C2C
 | | The molecular basis for the functional evolution of an organophosphate hydrolysing enzyme | | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ZINC ION, ... | | Authors: | Hong, N.-S, Jackson, C.J, Carr, P.D, Tokuriki, N, Baier, F, Yang, G. | | Deposit date: | 2018-01-08 | | Release date: | 2019-01-16 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.597 Å) | | Cite: | Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme.
Nat.Chem.Biol., 15, 2019
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3U8W
 | | Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Triazolopyridazinone inhibitor | | Descriptor: | 3-[3-(2-chloro-6-fluorophenyl)-5-ethyl-6-oxo-5,6-dihydro[1,2,4]triazolo[4,3-b]pyridazin-7-yl]-N-cyclopropyl-4-methylbenzamide, Mitogen-activated protein kinase 14 | | Authors: | Mohr, C, Jordan, S. | | Deposit date: | 2011-10-17 | | Release date: | 2012-08-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Identification of triazolopyridazinones as potent p38alpha inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
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4TY1
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8OUL
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8OUM
 | | Arf GTPase from the asgard Gerdarchaea : GerdArfR1 bound to GTP | | Descriptor: | GTP-binding protein, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | Authors: | Menetrey, J, Jackson, C, Dacks, J.B, Elias, M, Vargova, R. | | Deposit date: | 2023-04-24 | | Release date: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.67 Å) | | Cite: | Arf Family GTPases are present in Asgard archaea
To Be Published
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