5NOB
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![BU of 5nob by Molmil](/molmil-images/mine/5nob) | Crystal structure of human tankyrase 2 in complex with OD336 | Descriptor: | 1-[3-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxidanylidene-3~{H}-benzimidazole-5-carbonitrile, Tankyrase-2, ZINC ION | Authors: | Ignatev, A, Lehtio, L. | Deposit date: | 2017-04-11 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach. J. Med. Chem., 60, 2017
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3CPI
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![BU of 3cpi by Molmil](/molmil-images/mine/3cpi) | Crystal structure of yeast Rab-GDI | Descriptor: | Rab GDP-dissociation inhibitor | Authors: | Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. | Deposit date: | 2008-03-31 | Release date: | 2008-05-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
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3CPH
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![BU of 3cph by Molmil](/molmil-images/mine/3cph) | Crystal structure of Sec4 in complex with Rab-GDI | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rab GDP-dissociation inhibitor, ... | Authors: | Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. | Deposit date: | 2008-03-31 | Release date: | 2008-05-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
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3CPJ
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![BU of 3cpj by Molmil](/molmil-images/mine/3cpj) | Crystal structure of Ypt31 in complex with yeast Rab-GDI | Descriptor: | CHLORIDE ION, GTP-binding protein YPT31/YPT8, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. | Deposit date: | 2008-03-31 | Release date: | 2008-05-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
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5AEH
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![BU of 5aeh by Molmil](/molmil-images/mine/5aeh) | Crystal structure of human tankyrase 2 in complex with OD332 | Descriptor: | N-{4-[(2-chlorophenyl)(pyrimidin-4-yl)carbamoyl]phenyl}-4-methoxybenzamide, TANKYRASE-2, ZINC ION | Authors: | Ignatev, A, Lehtio, L. | Deposit date: | 2015-08-31 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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4CBU
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![BU of 4cbu by Molmil](/molmil-images/mine/4cbu) | Crystal structure of Plasmodium falciparum actin I | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-1, CALCIUM ION, ... | Authors: | Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I. | Deposit date: | 2013-10-16 | Release date: | 2014-04-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural Differences Explain Diverse Functions of Plasmodium Actins. Plos Pathog., 10, 2014
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4CBX
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![BU of 4cbx by Molmil](/molmil-images/mine/4cbx) | Crystal structure of Plasmodium berghei actin II | Descriptor: | ACTIN-2, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I. | Deposit date: | 2013-10-17 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Differences Explain Diverse Functions of Plasmodium Actins. Plos Pathog., 10, 2014
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4CBW
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![BU of 4cbw by Molmil](/molmil-images/mine/4cbw) | Crystal structure of Plasmodium berghei actin I with D-loop from muscle actin | Descriptor: | 1,4-DIETHYLENE DIOXIDE, ACTIN, ALPHA SKELETAL MUSCLE, ... | Authors: | Vahokoski, J, Bhargav, S.P, Desfosses, A, Andreadaki, M, Kumpula, E.P, Ignatev, A, Munico Martinez, S, Lepper, S, Frischknecht, F, Siden-Kiamos, I, Sachse, C, Kursula, I. | Deposit date: | 2013-10-17 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural Differences Explain Diverse Functions of Plasmodium Actins. Plos Pathog., 10, 2014
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5NSP
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![BU of 5nsp by Molmil](/molmil-images/mine/5nsp) | Crystal structure of TNKS2 in complex with OD334 | Descriptor: | 1-[4-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]phenyl]-2-oxidanylidene-3~{H}-benzimidazole-5-carbonitrile, BICARBONATE ION, GLYCEROL, ... | Authors: | Nkizinkiko, Y, Haikarainen, T, Lehtio, L. | Deposit date: | 2017-04-26 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach. J. Med. Chem., 60, 2017
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5ADQ
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![BU of 5adq by Molmil](/molmil-images/mine/5adq) | Crystal structure of human tankyrase 2 in complex with JW55 | Descriptor: | BICARBONATE ION, GLYCEROL, N-(4-(((4-(4-methoxyphenyl)oxan-4- yl)methyl)carbamoyl)phenyl)furan-2-carboxamide, ... | Authors: | Haikarainen, T, Lehtio, L. | Deposit date: | 2015-08-24 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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5ADS
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![BU of 5ads by Molmil](/molmil-images/mine/5ads) | |
5ADR
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![BU of 5adr by Molmil](/molmil-images/mine/5adr) | Crystal structure of human tankyrase 2 in complex with OD38 | Descriptor: | BICARBONATE ION, N-(4-(((4-(4-methoxyphenyl)oxan-4- yl)methyl)carbamoyl)phenyl)-5-methylfuran-2-carboxamide, SULFATE ION, ... | Authors: | Haikarainen, T, Lehtio, L. | Deposit date: | 2015-08-24 | Release date: | 2016-01-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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5ADT
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![BU of 5adt by Molmil](/molmil-images/mine/5adt) | Crystal structure of human tankyrase 2 in complex with OD73 | Descriptor: | BICARBONATE ION, N-[3-chloranyl-4-[[4-(4-methoxyphenyl)oxan-4-yl]methylcarbamoyl]phenyl]-2-methyl-1,3-oxazole-5-carboxamide, SULFATE ION, ... | Authors: | Haikarainen, T, Lehtio, L. | Deposit date: | 2015-08-24 | Release date: | 2016-01-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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