3J9S
 
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6OJ6
 | | In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (DLP_RNA) | | Descriptor: | Inner capsid protein VP2, RNA-directed RNA polymerase, Template, ... | | Authors: | Jenni, S, Salgado, E.N, Herrmann, T, Li, Z, Grant, T, Grigorieff, N, Trapani, S, Estrozi, L.F, Harrison, S.C. | | Deposit date: | 2019-04-10 | | Release date: | 2019-04-24 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase.
J.Mol.Biol., 431, 2019
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6OTF
 | | Symmetric reconstruction of human norovirus GII.2 Snow Mountain Virus Strain VLP in T=3 symmetry | | Descriptor: | Viral protein 1, ZINC ION | | Authors: | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | | Deposit date: | 2019-05-03 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
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8FMA
 | | Nodavirus RNA replication proto-crown, detergent-solubliized C11 multimer | | Descriptor: | RNA-directed RNA polymerase | | Authors: | Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P. | | Deposit date: | 2022-12-22 | | Release date: | 2023-02-01 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8FMB
 | | Nodavirus RNA replication protein A polymerase domain, local refinement | | Descriptor: | RNA-directed RNA polymerase | | Authors: | Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P. | | Deposit date: | 2022-12-22 | | Release date: | 2023-02-01 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (6.3 Å) | | Cite: | Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8FM9
 | | Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer | | Descriptor: | RNA-directed RNA polymerase | | Authors: | Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P. | | Deposit date: | 2022-12-22 | | Release date: | 2023-02-01 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
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9C8U
 | | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min | | Descriptor: | Isoform 2 of Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ... | | Authors: | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | | Deposit date: | 2024-06-13 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min
To Be Published
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9C8V
 | | Human DNA polymerase alpha/primase - CHAPSO (4 mM) | | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | | Authors: | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | | Deposit date: | 2024-06-13 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Human DNA polymerase alpha/primase - CHAPSO (4 mM)
To Be Published
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8VT0
 | | SPOT-RASTR - a cryo-EM specimen preparation technique that overcomes problems with preferred orientation and the air/water interface | | Descriptor: | Beta-galactosidase, MAGNESIUM ION | | Authors: | Esfahani, B.G, Randolph, P, Peng, R, Grant, T, Stroupe, M.E, Stagg, S.M. | | Deposit date: | 2024-01-25 | | Release date: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | SPOT-RASTR-A cryo-EM specimen preparation technique that overcomes problems with preferred orientation and the air/water interface.
Pnas Nexus, 3, 2024
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8VY3
 | | Human DNA polymerase alpha/primase - AavLEA1 (1:40 molar ratio) | | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | | Authors: | Abe, K.M, Li, G, Grant, T, Lim, C.J. | | Deposit date: | 2024-02-06 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Human PRC2 - AavLEA1 (1:40 molar ratio)
To Be Published
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2VY9
 | | Molecular architecture of the stressosome, a signal integration and transduction hub | | Descriptor: | ANTI-SIGMA-FACTOR ANTAGONIST | | Authors: | Marles-Wright, J, Grant, T, Delumeau, O, van Duinen, G, Firbank, S.J, Lewis, P.J, Murray, J.W, Newman, J.A, Quin, M.B, Race, P.R, Rohou, A, Tichelaar, W, van Heel, M, Lewis, R.J. | | Deposit date: | 2008-07-21 | | Release date: | 2008-10-14 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub
Science, 322, 2008
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8FWJ
 | | Structure of dodecameric KaiC-RS-S413E/S414E complexed with KaiB-RS solved by cryo-EM | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein KaiB, ... | | Authors: | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | Deposit date: | 2023-01-22 | | Release date: | 2023-03-22 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8FWI
 | | Structure of dodecameric KaiC-RS-S413E/S414E solved by cryo-EM | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein KaiC, ... | | Authors: | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | Deposit date: | 2023-01-22 | | Release date: | 2023-03-22 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8FAK
 | | DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli | | Descriptor: | DNA (5'-D(P*CP*AP*GP*AP*CP*TP*CP*AP*TP*TP*TP*AP*GP*CP*CP*CP*TP*TP*AP*TP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*AP*TP*AP*AP*GP*GP*GP*CP*TP*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ... | | Authors: | Duckworth, A.T, Ducos, P.L, McMillan, S.D, Satyshur, K.A, Blumenthal, K.H, Deorio, H.R, Larson, J.A, Sandler, S.J, Grant, T, Keck, J.L. | | Deposit date: | 2022-11-28 | | Release date: | 2023-05-10 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli.
Nat Commun, 14, 2023
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6OJ3
 | | In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (TLP) | | Descriptor: | Inner capsid protein VP2, RNA-directed RNA polymerase | | Authors: | Jenni, S, Salgado, E.N, Herrmann, T, Li, Z, Grant, T, Grigorieff, N, Trapani, S, Estrozi, L.F, Harrison, S.C. | | Deposit date: | 2019-04-10 | | Release date: | 2019-04-24 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase.
J.Mol.Biol., 431, 2019
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6OJ5
 | | In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (TLP_RNA) | | Descriptor: | Inner capsid protein VP2, RNA-directed RNA polymerase | | Authors: | Jenni, S, Salgado, E.N, Herrmann, T, Li, Z, Grant, T, Grigorieff, N, Trapani, S, Estrozi, L.F, Harrison, S.C. | | Deposit date: | 2019-04-10 | | Release date: | 2019-04-24 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (5.2 Å) | | Cite: | In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase.
J.Mol.Biol., 431, 2019
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6OJ4
 | | In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (DLP) | | Descriptor: | Inner capsid protein VP2, RNA-directed RNA polymerase | | Authors: | Jenni, S, Salgado, E.N, Herrmann, T, Li, Z, Grant, T, Grigorieff, N, Trapani, S, Estrozi, L.F, Harrison, S.C. | | Deposit date: | 2019-04-10 | | Release date: | 2019-04-24 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase.
J.Mol.Biol., 431, 2019
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6CNA
 | | GluN1-GluN2B NMDA receptors with exon 5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | Authors: | Furukawa, H, Grant, T, Grigorieff, N. | | Deposit date: | 2018-03-07 | | Release date: | 2018-10-03 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
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8DB3
 | | Crystal structure of KaiC with truncated C-terminal coiled-coil domain | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC | | Authors: | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | Deposit date: | 2022-06-14 | | Release date: | 2023-03-22 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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8DBA
 | | Crystal structure of dodecameric KaiC | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC, MAGNESIUM ION | | Authors: | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | | Deposit date: | 2022-06-14 | | Release date: | 2023-03-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | From primordial clocks to circadian oscillators.
Nature, 616, 2023
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5FXJ
 | | GluN1b-GluN2B NMDA receptor structure-Class X | | Descriptor: | GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1, NMDA 2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa H, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.25 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5FXI
 | | GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5FXK
 | | GluN1b-GluN2B NMDA receptor structure-Class Y | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5FXG
 | | GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5A22
 | | Structure of the L protein of vesicular stomatitis virus from electron cryomicroscopy | | Descriptor: | VESICULAR STOMATITIS VIRUS L POLYMERASE, ZINC ION | | Authors: | Liang, B, Li, Z, Jenni, S, Rameh, A.A, Morin, B.M, Grant, T, Grigorieff, N, Harrison, S.C, Whelan, S.P.J. | | Deposit date: | 2015-05-06 | | Release date: | 2015-08-19 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Cell(Cambridge,Mass.), 162, 2015
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