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1F1W
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BU of 1f1w by Molmil
SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN
Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, S(PTR)VNVQN PHOSPHOPEPTIDE
Authors:Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F.
Deposit date:2000-05-20
Release date:2000-07-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for specificity switching of the Src SH2 domain.
Mol.Cell, 5, 2000
1F2F
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BU of 1f2f by Molmil
SRC SH2 THREF1TRP MUTANT
Descriptor: PHOSPHATE ION, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
Authors:Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F.
Deposit date:2000-05-24
Release date:2000-07-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for specificity switching of the Src SH2 domain.
Mol.Cell, 5, 2000
6NJG
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BU of 6njg by Molmil
Ubiquitin Variant in Complex with Ubiquitin Interacting Motif
Descriptor: Polyubiquitin-B, Vacuolar protein sorting-associated protein 27
Authors:Manczyk, N, Sicheri, F.
Deposit date:2019-01-03
Release date:2019-03-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif.
Protein Sci., 28, 2019
4JMG
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BU of 4jmg by Molmil
Crystal structure of the synthetic protein in complex with pY peptide
Descriptor: Clamp Ptpn11_pY580, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 11
Authors:Yasui, N, Smith, L, Koide, S.
Deposit date:2013-03-14
Release date:2014-04-23
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.403 Å)
Cite:Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.
Mol.Cell, 54, 2014
4JMH
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BU of 4jmh by Molmil
Crystal structure of synthetic protein in complex with double pY peptide
Descriptor: Clamp Shc1_pY239/240, SHC-transforming protein 1
Authors:Yasui, N, Smith, L, Koide, S.
Deposit date:2013-03-14
Release date:2014-04-23
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.408 Å)
Cite:Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.
Mol.Cell, 54, 2014
5CW6
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BU of 5cw6 by Molmil
Structure of metal dependent enzyme DrBRCC36
Descriptor: DrBRCC36, ZINC ION
Authors:Zeqiraj, E.
Deposit date:2015-07-27
Release date:2015-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.193 Å)
Cite:Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.
Mol.Cell, 59, 2015
5CW4
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BU of 5cw4 by Molmil
Structure of CfBRCC36-CfKIAA0157 complex (Selenium Edge)
Descriptor: BRCA1/BRCA2-containing complex subunit 3, GLYCEROL, Protein FAM175B, ...
Authors:Zeqiraj, E.
Deposit date:2015-07-27
Release date:2015-09-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.543 Å)
Cite:Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.
Mol.Cell, 59, 2015
5CW3
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BU of 5cw3 by Molmil
Structure of CfBRCC36-CfKIAA0157 complex (Zn Edge)
Descriptor: BRCA1/BRCA2-containing complex subunit 3, Protein FAM175B, ZINC ION
Authors:Zeqiraj, E.
Deposit date:2015-07-27
Release date:2015-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.
Mol.Cell, 59, 2015
5CW5
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BU of 5cw5 by Molmil
Structure of CfBRCC36-CfKIAA0157 complex (QSQ mutant)
Descriptor: BRCA1/BRCA2-containing complex subunit 3, Protein FAM175B
Authors:Zeqiraj, E.
Deposit date:2015-07-27
Release date:2015-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.736 Å)
Cite:Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.
Mol.Cell, 59, 2015
3CD3
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BU of 3cd3 by Molmil
Crystal structure of phosphorylated human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide
Descriptor: CHLORIDE ION, Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, ...
Authors:Filippakopoulos, P, Salah, E, Cooper, C, Picaud, S.S, Elkins, J.M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2008-02-26
Release date:2008-03-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation
Cell(Cambridge,Mass.), 134, 2008
3CBL
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BU of 3cbl by Molmil
Crystal structure of human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide
Descriptor: Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, Synthetic peptide
Authors:Filippakopoulos, P, Salah, E, Cooper, C, Picaud, S.S, Elkins, J.M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2008-02-22
Release date:2008-03-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation
Cell(Cambridge,Mass.), 134, 2008
3BKB
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BU of 3bkb by Molmil
Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES)
Descriptor: 1,2-ETHANEDIOL, Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, ...
Authors:Filippakopoulos, P, Salah, E, Fedorov, O, Cooper, C, Ugochukwu, E, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2007-12-06
Release date:2007-12-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation
Cell(Cambridge,Mass.), 134, 2008
3SO8
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BU of 3so8 by Molmil
Crystal Structure of ANKRA
Descriptor: Ankyrin repeat family A protein 2
Authors:Xu, C, Bochkarev, A, Bian, C.B, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-06-30
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3T04
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BU of 3t04 by Molmil
Crystal structure of monobody 7c12/abl1 sh2 domain complex
Descriptor: GLYCEROL, MONOBODY 7C12, SULFATE ION, ...
Authors:Wojcik, J.B, Wyrzucki, A.M, Koide, S.
Deposit date:2011-07-19
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis.
Cell(Cambridge,Mass.), 147, 2011
3UZD
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BU of 3uzd by Molmil
Crystal structure of 14-3-3 GAMMA
Descriptor: 14-3-3 protein gamma, Histone deacetylase 4, MAGNESIUM ION, ...
Authors:Xu, C, Bian, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-07
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V2X
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BU of 3v2x by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
Descriptor: Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V2O
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BU of 3v2o by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
Descriptor: Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V31
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BU of 3v31 by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
Descriptor: Ankyrin repeat family A protein 2, CHLORIDE ION, Histone deacetylase 4, ...
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3UXG
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BU of 3uxg by Molmil
Crystal structure of RFXANK
Descriptor: DNA-binding protein RFXANK, Histone deacetylase 4, UNKNOWN ATOM OR ION
Authors:Tempel, W, Chao, X, Bian, C, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-05
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V30
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BU of 3v30 by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK
Descriptor: DNA-binding protein RFX5, DNA-binding protein RFXANK
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012

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数据于2024-11-06公开中

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