6H6E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h6e by Molmil](/molmil-images/mine/6h6e) | PTC3 holotoxin complex from Photorhabdus luminecens in prepore state (TcdA1, TcdB2, TccC3) | Descriptor: | TcdA1, TcdB2,TccC3 | Authors: | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | Deposit date: | 2018-07-27 | Release date: | 2018-10-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Tc toxin activation requires unfolding and refolding of a beta-propeller. Nature, 563, 2018
|
|
4BED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bed by Molmil](/molmil-images/mine/4bed) | |
5LKI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lki by Molmil](/molmil-images/mine/5lki) | Cryo-EM structure of the Tc toxin TcdA1 in its pore state | Descriptor: | TcdA1 | Authors: | Gatsogiannis, C, Merino, F, Prumbaum, D, Roderer, D, Leidreiter, F, Meusch, D, Raunser, S. | Deposit date: | 2016-07-22 | Release date: | 2016-08-31 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Membrane insertion of a Tc toxin in near-atomic detail. Nat.Struct.Mol.Biol., 23, 2016
|
|
5LKH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lkh by Molmil](/molmil-images/mine/5lkh) | Cryo-EM structure of the Tc toxin TcdA1 in its pore state (obtained by flexible fitting) | Descriptor: | TcdA1 | Authors: | Gatsogiannis, C, Merino, F, Prumbaum, D, Roderer, D, Leidreiter, F, Meusch, D, Raunser, S. | Deposit date: | 2016-07-22 | Release date: | 2016-08-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Membrane insertion of a Tc toxin in near-atomic detail. Nat.Struct.Mol.Biol., 23, 2016
|
|
6H6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h6f by Molmil](/molmil-images/mine/6h6f) | PTC3 holotoxin complex from Photorhabdus luminiscens - Mutant TcC-D651A | Descriptor: | TcdA1, TcdB2,TccC3,TccC3 | Authors: | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | Deposit date: | 2018-07-27 | Release date: | 2018-10-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Tc toxin activation requires unfolding and refolding of a beta-propeller. Nature, 563, 2018
|
|
6H6G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h6g by Molmil](/molmil-images/mine/6h6g) | Crystal Structure of TcdB2-TccC3 without hypervariable C-terminal region | Descriptor: | TcdB2,TccC3 | Authors: | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | Deposit date: | 2018-07-27 | Release date: | 2018-10-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | Tc toxin activation requires unfolding and refolding of a beta-propeller. Nature, 563, 2018
|
|
6SFW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sfw by Molmil](/molmil-images/mine/6sfw) | |
6SFX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sfx by Molmil](/molmil-images/mine/6sfx) | |
6XTB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xtb by Molmil](/molmil-images/mine/6xtb) | |
8C0V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c0v by Molmil](/molmil-images/mine/8c0v) | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in single seam state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ruettermann, M, Koci, M, Lill, P, Geladas, E.D, Kaschani, F, Klink, B.U, Erdmann, R, Gatsogiannis, C. | Deposit date: | 2022-12-19 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate. Nat Commun, 14, 2023
|
|
8C0W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c0w by Molmil](/molmil-images/mine/8c0w) | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in twin seam state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ruettermann, M, Koci, M, Lill, P, Geladas, E.D, Kaschani, F, Klink, B.U, Erdmann, R, Gatsogiannis, C. | Deposit date: | 2022-12-19 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate. Nat Commun, 14, 2023
|
|
6ZXK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zxk by Molmil](/molmil-images/mine/6zxk) | Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1B) arrangement | Descriptor: | Lethal factor, Protective antigen | Authors: | Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. | Deposit date: | 2020-07-29 | Release date: | 2020-09-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. Plos Pathog., 16, 2020
|
|
6ZXJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zxj by Molmil](/molmil-images/mine/6zxj) | Fully-loaded anthrax lethal toxin in its heptameric pre-pore state, in which the third lethal factor is masked out (PA7LF3-masked) | Descriptor: | Lethal factor, Protective antigen | Authors: | Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. | Deposit date: | 2020-07-29 | Release date: | 2020-09-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. Plos Pathog., 16, 2020
|
|
6ZXL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zxl by Molmil](/molmil-images/mine/6zxl) | Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1A) arrangement | Descriptor: | Lethal factor, Protective antigen | Authors: | Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. | Deposit date: | 2020-07-29 | Release date: | 2020-09-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. Plos Pathog., 16, 2020
|
|
6XT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xt9 by Molmil](/molmil-images/mine/6xt9) | Subunits BBS 1,4,8,9,18 of the human BBSome complex | Descriptor: | BBSome-interacting protein 1, Bardet-Biedl syndrome 1 protein, Bardet-Biedl syndrome 4 protein, ... | Authors: | Klink, B.U, Raunser, S, Gatsogiannis, C. | Deposit date: | 2020-01-15 | Release date: | 2020-01-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the human BBSome core complex. Elife, 9, 2020
|
|
6R83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r83 by Molmil](/molmil-images/mine/6r83) | CryoEM structure and molecular model of squid hemocyanin (Todarodes pacificus , TpH) | Descriptor: | Hemocyanin subunit 1 | Authors: | Tanaka, Y, Kato, S, Stabrin, M, Raunser, S, Matsui, T, Gatsogiannis, C. | Deposit date: | 2019-03-31 | Release date: | 2019-05-08 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Cryo-EM reveals the asymmetric assembly of squid hemocyanin. Iucrj, 6, 2019
|
|
6RW8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rw8 by Molmil](/molmil-images/mine/6rw8) | Cryo-EM structure of Xenorhabdus nematophila XptA1 | Descriptor: | A component of insecticidal toxin complex (Tc) | Authors: | Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S. | Deposit date: | 2019-06-04 | Release date: | 2019-10-23 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Common architecture of Tc toxins from human and insect pathogenic bacteria. Sci Adv, 5, 2019
|
|
4O9Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o9y by Molmil](/molmil-images/mine/4o9y) | Crystal Structure of TcdA1 | Descriptor: | TcdA1 | Authors: | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | Deposit date: | 2014-01-03 | Release date: | 2014-02-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.502 Å) | Cite: | Mechanism of Tc toxin action revealed in molecular detail. Nature, 508, 2014
|
|
4O9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o9x by Molmil](/molmil-images/mine/4o9x) | Crystal Structure of TcdB2-TccC3 | Descriptor: | MERCURY (II) ION, TcdB2, TccC3 | Authors: | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | Deposit date: | 2014-01-03 | Release date: | 2014-02-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Mechanism of Tc toxin action revealed in molecular detail. Nature, 508, 2014
|
|
7QLA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qla by Molmil](/molmil-images/mine/7qla) | Structure of the Rab GEF complex Mon1-Ccz1 | Descriptor: | Ccz1, Vacuolar fusion protein MON1 | Authors: | Klink, B.U, Herrmann, E, Antoni, C, Langemeyer, L, Kiontke, S, Gatsogiannis, C, Ungermann, C, Raunser, S, Kuemmel, D. | Deposit date: | 2021-12-20 | Release date: | 2022-02-09 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7PTX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ptx by Molmil](/molmil-images/mine/7ptx) | Alpha-latrocrustotoxin monomer | Descriptor: | Alpha-latrocrustotoxin-Lt1a | Authors: | Chen, M, Gatsogiannis, C. | Deposit date: | 2021-09-27 | Release date: | 2021-12-08 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.03 Å) | Cite: | Molecular architecture of black widow spider neurotoxins. Nat Commun, 12, 2021
|
|
7PTY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pty by Molmil](/molmil-images/mine/7pty) | Delta-latroinsectotoxin dimer | Descriptor: | Delta-latroinsectotoxin-Lt1a | Authors: | Chen, M, Gatsogiannis, C. | Deposit date: | 2021-09-27 | Release date: | 2021-12-08 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.63 Å) | Cite: | Molecular architecture of black widow spider neurotoxins. Nat Commun, 12, 2021
|
|
6G1K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g1k by Molmil](/molmil-images/mine/6g1k) | Electron cryo-microscopy structure of the canonical TRPC4 ion channel | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily c member 4a | Authors: | Vinayagam, D, Mager, T, Apelbaum, A, Bothe, A, Merino, F, Hofnagel, O, Gatsogiannis, C, Raunser, S. | Deposit date: | 2018-03-21 | Release date: | 2018-05-02 | Last modified: | 2018-08-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Electron cryo-microscopy structure of the canonical TRPC4 ion channel. Elife, 7, 2018
|
|
8ATD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8atd by Molmil](/molmil-images/mine/8atd) | Wild type hexamer oxalyl-CoA synthetase (OCS) | Descriptor: | Oxalate--CoA ligase | Authors: | Lill, P, Burgi, J, Raunser, S, Wilmanns, M, Gatsogiannis, C. | Deposit date: | 2022-08-23 | Release date: | 2023-02-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase. Biol.Chem., 404, 2023
|
|
7Q5P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q5p by Molmil](/molmil-images/mine/7q5p) | Structure of VgrG1 from Pseudomonas protegens. | Descriptor: | Type VI secretion protein VgrG | Authors: | Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S. | Deposit date: | 2021-11-04 | Release date: | 2021-12-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of a bacterial Rhs effector exported by the type VI secretion system. Plos Pathog., 18, 2022
|
|